US3862954A
Expired / Lapsed
US
⏱️ 0.0 years remaining
1,3,5-Substituted-1,2,4-triazoles and their preparation
Assignee: Gruppo Lepetit SpA
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Filing: 1973-12-06
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Granted: 1975-01-28
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Expires: 1993-12-06
Abstract
Abstract WHEREIN R is lower alkyl, R1 is pyridyl, lower alkyl-substituted pyridyl, thienyl, lower alkyl-substituted thienyl, furyl, lower alkyl-substituted furyl, indolyl, pyrrolyl or lower alkylsubstituted pyrrolyl; R2 is hydrogen or hydroxy; and a salt thereof with a pharmaceutically acceptable acid. The compounds of the foregoing class have depressant activity on the central nervous system coupled with a low toxicity. A pharmacologically-active triazole represented by the formula
Inventors
- 👤 Amedeo Omodei-Sale
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 05:45
CPC Classifications
C; C07; C07D; C07D401/00; C07D401/02; C07D401/04; C07D403/00; C07D403/02; C07D403/04; C07D405/00; C07D405/02; C07D405/04; C07D409/00; C07D409/02; C07D409/04
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
8 words
A compound of claim 1 which is 5-(o-hydroxymethylphenyl)-1-methyl-3-(3-pyridyl)-1H-1,2,4-triazole.
Claim 2
Dependent Claim
8 words
A compound of claim 1 which is 5-(o-hydroxymethylphenyl)-1-methyl-3-(6-methyl-2-pyridyl)-1H-1,2,4-triazole.
Claim 3
Dependent Claim
8 words
A compound of claim 1 which is 5-(o-hydroxymethylphenyl)-1-methyl-3-(2-furyl)-1H-1,2,4-triazole.
Claim 4
Dependent Claim
8 words
A compound of claim 1 which is 5-(o-hydroxymethylphenyl)-1-methyl-3-(5-methyl-2-furyl)-1H-1,2,4-triazole.
Claim 5
Dependent Claim
8 words
A compound of claim 1 which is 1-methyl-3-(6-methyl-2-pyridyl-5-(o-tolyl)-1H-1,2,4-triazole.
Claim 6
Dependent Claim
8 words
A compound of claim 1 which is 1-methyl-3-(5-methyl-2-furyl)-5-(o-tolyl)-1H-1,2,4-triazole.
Claim 7
Dependent Claim
8 words
A compound of claim 1 which is 1-methyl-3-(1-methyl-2-pyrrolyl)-5-(o-tolyl)-1H-1,2,4-triazole.
Claim 8
Dependent Claim
8 words
A compound of claim 1 which is 1-methyl-3-(2-furyl)-5-(o-tolyl)-1H-1,2,4-triazole.
Claim 9
Dependent Claim
9 words
A process for preparing a compound of the formula
Claim 10
Dependent Claim
18 words
A process as claimed in claim 10 which comprises submitting to the said acid-catalyzed rearrangement the said 4-hydrazino-1H-2,3-benzoxazine.
Claim 11
Dependent Claim
18 words
A process as claimed in claim 10 which comprises catalytically hydrogenating the hydroxymethyl radical to the methyl radical.
References Cited (Backward Citations)
GB1225612A
Cited
DE2147882A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-01-27 | 1978-07-29 | 1979-01-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-01-27 | 1982-07-29 | 1983-01-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-01-27 | 1986-07-29 | 1987-01-28 | $7700.00 | Window Closed / Lapsed |