US4110333A
Expired / Lapsed
US
⏱️ 0.0 years remaining
1,3-Dihydro-1-[3-(1-piperidinyl)propyl]-2H-benzimidazol-2-ones and related compounds
Assignee: Janssen Pharmaceutica NV
•
Filing: 1977-07-20
•
Granted: 1978-08-29
•
Expires: 1997-07-20
Abstract
Abstract Chemical compounds of the formula ##STR1## wherein B, R 1 , R 2 , R 3 , R 7 , R 8 , m and n are as defined hereinbelow, which compounds are intermediates for the preparation of antiemetic agents.
Inventors
- 👤 Jan Vandenberk
- 👤 Ludo E. J. Kennis
- 👤 Marcel J. M. C. Van der Aa
- 👤 Albert H. M. Th. Van Heertum
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 14:58
CPC Classifications
C; C07; C07D; C07D235/00; C07D235/02; C07D235/04; C07D235/06; C07D211/00; C07D211/04; C07D211/06; C07D211/36; C07D211/56; C07D211/58; C07D235/24; C07D235/26
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
125 words
A chemical compound having the formula: ##STR62## wherein: R 1 and R 2 are each independently selected from the group consisting of hydrogen, halo, lower alkyl and trifluoromethyl; B is a member selected from the group consisting of the bivalent radicals ##STR63## --N═N-- and --N═CH--, said L being a member selected from the group consisting of hydrogen, lower alkyl, lower alkylcarbonyl and lower alkenyl, and said bivalent radicals being attached to the benzene nucleus with their heteroatom; R 3 is a member selected from the group consisting of hydrogen and methyl; m and n are each an integer of from 1 to 2 inclusive; and R 7 and R 8 are each independently selected from the group consisting of hydrogen, halo, lower alkyl and trifluoromethyl.
Claim 2
Dependent Claim
125 words
A chemical compound having the formula: ##STR62## wherein: R 1 and R 2 are each independently selected from the group consisting of hydrogen, halo, lower alkyl and trifluoromethyl; B is a member selected from the group consisting of the bivalent radicals ##STR63## --N═N-- and --N═CH--, said L being a member selected from the group consisting of hydrogen, lower alkyl, lower alkylcarbonyl and lower alkenyl, and said bivalent radicals being attached to the benzene nucleus with their heteroatom; R 3 is a member selected from the group consisting of hydrogen and methyl; m and n are each an integer of from 1 to 2 inclusive; and R 7 and R 8 are each independently selected from the group consisting of hydrogen, halo, lower alkyl and trifluoromethyl.
References Cited (Backward Citations)
US3634441A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-08-28 | 1982-02-27 | 1982-08-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-08-28 | 1986-02-27 | 1986-08-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-08-28 | 1990-02-27 | 1990-08-29 | $7700.00 | Window Closed / Lapsed |