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US4105034A Expired / Lapsed US ⏱️ 0.0 years remaining

Poly(alkylene oxalate) absorbable coating for sutures

Assignee: Ethicon Inc
•
Filing: 1977-06-10
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Granted: 1978-08-08
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Expires: 1997-06-10
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Abstract

Abstract The tie-down properties of multifilament surgical sutures are improved by coating the suture with an absorbable composition comprising a poly(alkylene oxalate) wherein the alkylene is a C6 or a mixture of C4 to C12 alkylene moieties. Braided sutures coated with from about 1 to 15 percent by weight of the composition are characterized by a smooth knot tie-down under both wet and dry conditions.

Inventors

  • 👤 Shalaby W. Shalaby
  • 👤 Dennis D. Jamiolkowski

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 19:10
CPC Classifications
A; A61; A61L; A61L17/00; A61L17/14; A61L17/145; Y; Y10; Y10T; Y10T428/00; Y10T428/29; Y10T428/2913; Y10T428/2933; Y10T428/2938

Claims Analysis

Total Claims: 35
Claim 1
Independent Claim 84 words
A synthetic, multifilament suture having improved tie-down properties, said suture being coated with from about 1 to 15 percent by weight of a composition comprising a poly(alkylene oxalate) wherein the alkylene is C 6 or a mixture of C 4 - to C 12 -alkylene moieties, said poly(alkylene oxalate) having a melting point below about 100° C and an inherent viscosity of from about 0.1 to 1.2 as determined at 25° C on a 0.1 percent solution of polymer in CHCl 3 or hexafluoroisopropanol.
Claim 2
Dependent Claim 84 words
A synthetic, multifilament suture having improved tie-down properties, said suture being coated with from about 1 to 15 percent by weight of a composition comprising a poly(alkylene oxalate) wherein the alkylene is C 6 or a mixture of C 4 - to C 12 -alkylene moieties, said poly(alkylene oxalate) having a melting point below about 100° C and an inherent viscosity of from about 0.1 to 1.2 as determined at 25° C on a 0.1 percent solution of polymer in CHCl 3 or hexafluoroisopropanol.
Claim 3
Dependent Claim 14 words
A suture of claim 1, wherein the multifilament suture is of a braided construction.
Claim 4
Dependent Claim 12 words
A suture of claim 1, wherein said poly(alkylene oxalate) is poly(hexamethylene oxalate).
Claim 5
Dependent Claim 22 words
A suture of claim 1, wherein the poly(alkylene oxalate) comprises C 4 -, C 6 -, and C 8 -alkylene oxalate moieties.
Claim 6
Dependent Claim 46 words
A suture of claim 4, wherein the C 6 -alkylene oxalate comprises from about 30 to 80 percent of the total poly(alkylene oxalate), and the C 4 - and C 8 -alkylene oxalates each comprise from about 10 to 40 percent of the total poly(alkylene oxalate).
Claim 7
Dependent Claim 25 words
A suture of claim 1 wherein the poly(alkylene oxalate) comprises C 4 -, C 6 -, C 8 -, and C 12 -alkylene oxalate moieties.
Claim 8
Dependent Claim 34 words
A suture of claim 6 wherein the C 4 -, C 6 -, C 8 -, and C 12 -alkylene oxalates each comprise from about 10 to 40 percent of the total poly(alkylene oxalate).
Claim 9
Dependent Claim 19 words
A suture of claim 1 wherein the poly(alkylene oxalate) comprises C 4 - and C 10 -alkylene oxalate moieties.
Claim 10
Dependent Claim 28 words
A suture of claim 8 wherein the C 4 - and C 10 -alkylene oxalates each comprise from about 10 to 90 percent of the total poly(alkylene oxalate).
Claim 11
Dependent Claim 19 words
A suture of claim 1 wherein the poly(alkylene oxalate) comprises C 4 - and C 8 -alkylene oxalate moieties.
Claim 12
Dependent Claim 28 words
A suture of claim 10 wherein the C 4 - and C 8 -alkylene oxalates each comprise from about 10 to 90 percent of the total poly(alkylene oxalate).
Claim 13
Dependent Claim 19 words
A suture of claim 1 wherein the poly(alkylene oxalate) comprises C 4 - and C 6 -alkylene oxalate moieties.
Claim 14
Dependent Claim 28 words
A suture of claim 12 wherein the C 4 - and C 6 -alkylene oxalates each comprise from about 10 to 90 percent of the total poly(alkylene oxalate).
Claim 15
Dependent Claim 19 words
A suture of claim 1 wherein the poly(alkylene oxalate) comprises C 6 - and C 10 -alkylene oxalate moieties.
Claim 16
Dependent Claim 28 words
A suture of claim 14 wherein the C 6 - and C 10 -alkylene oxalates each comprise from about 10 to 90 percent of the total poly(alkylene oxalate).
Claim 17
Dependent Claim 20 words
A suture of claim 1 wherein the poly(alkylene oxalate) comprises C 6 - and C 8 - alkylene oxalate moieties.
Claim 18
Dependent Claim 28 words
A suture of claim 16 wherein the C 6 - and C 8 -alkylene oxalates each comprise from about 10 to 90 percent of the total poly(alkylene oxalate).
Claim 19
Dependent Claim 17 words
A suture of claim 1 coated with from about 5 to 10 percent of the said composition.
Claim 20
Dependent Claim 20 words
A suture of claim 2 wherein the synthetic absorbable suture is comprised of homopolymers or copolymers of lactide and glycolide.
Claim 21
Dependent Claim 24 words
A suture of claim 19 wherein said suture is comprised of a copolymer derived from 10 weight percent lactide and 90 weight percent glycolide.
Claim 22
Dependent Claim 13 words
A suture of claim 20 wherein the multifilament suture is a braided suture.
Claim 23
Dependent Claim 14 words
A suture of claim 2 wherein the synthetic absorbable suture is comprised of poly(p-dioxanone).
Claim 24
Dependent Claim 14 words
A suture of claim 22 wherein the multifilament suture is of a braided construction.
Claim 25
Independent Claim 87 words
A method for improving the tie-down characteristics of a multifilament suture which comprises coating said suture with from about 1 to 15 percent by weight of a composition comprising a poly(alkylene oxalate) wherein the alkylene is C 6 or a mixture of C 4 to C 12 alkylene moieties, said poly(alkylene oxalate) having a melting point below about 100° C and an inherent viscosity of from about 0.1 to 1.2 as determined at 25° C on a 0.1 percent solution of polymer in CHCl 3 or hexafluoroisopropanol.
Claim 26
Independent Claim 87 words
A method for improving the tie-down characteristics of a multifilament suture which comprises coating said suture with from about 1 to 15 percent by weight of a composition comprising a poly(alkylene oxalate) wherein the alkylene is C 6 or a mixture of C 4 to C 12 alkylene moieties, said poly(alkylene oxalate) having a melting point below about 100° C and an inherent viscosity of from about 0.1 to 1.2 as determined at 25° C on a 0.1 percent solution of polymer in CHCl 3 or hexafluoroisopropanol.
Claim 27
Dependent Claim 12 words
The method of claim 24 wherein the poly(alkylene oxalate) is poly(hexamethylene oxalate).
Claim 28
Dependent Claim 56 words
The method of claim 24 wherein the poly(alkylene oxalate) comprises alkylene oxalate moieties selected from the group consisting of C 4 - and C 6 -, C 4 - and C 8 -, C 4 - and C 10 -, C 6 - and C 8 -, and C 6 - and C 10 -alkylene oxalates.
Claim 29
Dependent Claim 27 words
The method of claim 26 wherein each alkylene oxalate is present in an amount equal to from about 10 to 90 percent of the total poly(alkylene oxalate).
Claim 30
Dependent Claim 22 words
The method of claim 24 wherein the poly(alkylene oxalate) comprises C 4 -, C 6 - and C 8 -alkylene oxalate moieties.
Claim 31
Dependent Claim 46 words
The method of claim 28 wherein the C 6 -alkylene oxalate comprises from about 30 to 80 percent of the total poly(alkylene oxalate) and the C 4 - and C 8 -alkylene oxalates each comprise from about 10 to 40 percent of the total poly(alkylene oxalate).
Claim 32
Dependent Claim 25 words
The method of claim 24 wherein the poly(alkylene oxalate) comprises C 4 -, C 6 -, C 8 -, and C 12 -alkylene oxalate moieties.
Claim 33
Dependent Claim 34 words
The method of claim 30 wherein the C 4 -, C 6 -, C 8 -, and C 12 -alkylene oxalates each comprise from about 10 to 40 percent of the total poly(alkylene oxalate).
Claim 34
Dependent Claim 28 words
The method of claim 24 wherein said suture is composed of an absorbable synthetic polymer selected from the group consisting of homopolymers and copolymers of lactide and glycolide.
Claim 35
Dependent Claim 12 words
The method of claim 24 wherein said suture is composed of poly(p-dioxanone).

References Cited (Backward Citations)

US3322125A Cited
US3527650A Cited
DE2139455A1 Cited
US4027676A Cited
US4043344A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1981-08-07 1982-02-06 1982-08-08 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1985-08-07 1986-02-06 1986-08-08 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1989-08-07 1990-02-06 1990-08-08 $7700.00 Window Closed / Lapsed

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