Compositions to control the chronic effects of exposure to sunlight comprising conjugated dienes

Claim 2

A composition adapted for topical application and capable of inhibiting chronic damage to skin induced by ultraviolet radiation in the range of 2,950 A to 4000 A, comprising an effective ultraviolet absorbing amount from about 0.001% to about 25%, by weight, of a conjugated diene ester or amide having an acid portion derived from p-methoxy cinnamic acid, p-aminobenzoic acid, salicylic acid, or p-dimethyl amino benzoic acid, and an alcohol portion derived from: 2,4-hexadien-1-ol, 3,5-heptadien-1-ol, 3,5-octadien-1,8-diol, 3-methylene-4-penten-1-ol, 3-ethylidene-4-hexen-1-ol, 6,7-bis(1-hydroxy-2-ethyl)-5,7-dodecadiene, 3-(1-hydroxy-2-ethyl)-1,8-dihydroxy-3,5-octadiene, 9,11-dodecadien-1-ol, octa-5,7-dien-1,2-diol, 4,6-heptadien-2-ol, 2,9-dihydroxy-2-methyl-4,6-nonadiene, 2,9-dihydroxy-4,6-decadiene, 5-hydroxymethyl-1,3-cyclohexadiene, 2-(1-hydroxy-2-ethyl)-1,3-cyclohexadiene, 2,3-bis(1-hydroxy-2-ethyl)-1,3-cyclohexadiene, 2-(1-hydroxy-2-ethyl)-1,4-dimethyl-3-butyl-1,3-cyclohexadiene, 1-(1-hydroxy-2-ethyl)-1,3-cycloheptadiene, 2-(1-hydroxy-2-ethyl)-1,3-cycloheptadiene, 2,6-bis(1-hydroxy-2-ethyl)-1,3-cycloheptadiene, 6-(1-hydroxy-2-ethyl)-1,3-cycloheptadiene, 1-(1-hydroxy-2-ethyl)-cyclonona-1,3-diene, 7-hydroxy-1,3-cyclononadiene, 7-(1-hydroxy-2-ethyl)-1,3-cyclononadiene, 1-(1-hydroxy-2-ethyl)-1,3-cyclotetradecadiene, 2-(1-hydroxy-2-ethyl)-Δ 1 (2),8 -hexalin, Δ 1 (2),8 -6-hexalol, or 1,1'-bis cyclohexene-4-ol; or an amine portion derived from: 2.

Claim 3

4-hexadien-1-amine, 1,6-diamino-2,4-hexadiene, 2-lower alkyl amino-1,3-butadiene, 1-amino-3,5-heptadiene, 1-amino-3,5-hexadiene, 1,8-diamino-3,5-octadiene, 3-methylene-4-hexene-1-amine, 3-(1-amino-2-ethyl)-2,4-hexadiene, 1-amino-4,6-dodecadiene, 1-di lower alkyl amino-3,5-hexadiene, 1,9-bis(di-lower alkyl amino)-4,6-nonadiene, 1-di-methyl amino-3-methylene-4-hexene, 1-N-phenyl-N-lower alkyl amino-3,5-hexdadiene, 1-N-piperidino-3,5-hexadiene, 1-lower alkyl amino-3,5-heptadiene, 1,2-dihydropyridine, 3-vinyl-1,2,5,6-tetrahydropyridine, 2,7-dihydroazepine, 2,3,8,9-tetrahydroazonine, 4-(1-hydroxy-3-butenyl)-1,2,5,6-tetrahydropyridine, 2,3,8,9-tetrahydro-N-lower alkyl azonine, 1-(2-amino-1-ethyl)-1,3-cyclononadiene, 2-(2-amino-1-ethyl)-1,3-cyclononadiene, 1-(2-di-lower alkyl amino-1-ethyl)-1,3-cyclononadiene, 1,4-bis(2-di-methyl amino-1-ethyl)-1,3-cyclononadiene, or 1-(2-piperidino-1-ethyl)-1,3-cyclononadiene; in a skin compatible vehicle containing from about 0.1% to about 10%, by weight, surfactant wherein the surfactant is a nonionic, cationic or amphoteric surfactant or from about 0.01% to about 0.5%, by weight, of a

Claim 4

4-hexadien-1-amine, 1,6-diamino-2,4-hexadiene, 2-lower alkyl amino-1,3-butadiene, 1-amino-3,5-heptadiene, 1-amino-3,5-hexadiene, 1,8-diamino-3,5-octadiene, 3-methylene-4-hexene-1-amine, 3-(1-amino-2-ethyl)-2,4-hexadiene, 1-amino-4,6-dodecadiene, 1-di lower alkyl amino-3,5-hexadiene, 1,9-bis(di-lower alkyl amino)-4,6-nonadiene, 1-di-methyl amino-3-methylene-4-hexene, 1-N-phenyl-N-lower alkyl amino-3,5-hexdadiene, 1-N-piperidino-3,5-hexadiene, 1-lower alkyl amino-3,5-heptadiene, 1,2-dihydropyridine, 3-vinyl-1,2,5,6-tetrahydropyridine, 2,7-dihydroazepine, 2,3,8,9-tetrahydroazonine, 4-(1-hydroxy-3-butenyl)-1,2,5,6-tetrahydropyridine, 2,3,8,9-tetrahydro-N-lower alkyl azonine, 1-(2-amino-1-ethyl)-1,3-cyclononadiene, 2-(2-amino-1-ethyl)-1,3-cyclononadiene, 1-(2-di-lower alkyl amino-1-ethyl)-1,3-cyclononadiene, 1,4-bis(2-di-methyl amino-1-ethyl)-1,3-cyclononadiene, or 1-(2-piperidino-1-ethyl)-1,3-cyclononadiene; in a skin compatible vehicle containing from about 0.1% to about 10%, by weight, surfactant wherein the surfactant is a nonionic, cationic or amphoteric surfactant or from about 0.01% to about 0.5%, by weight, of a

Claim 5

non-soap anionic surfactant. 2. A composition adapted for topical application and capable of inhibiting chronic damage to skin induced by ultraviolet radiation in the range of 2,950 A to 4000 A, comprising an effective ultraviolet absorbing amount from about 0.001% to about 25%, by weight of 3,5-hexadienyl octyl sulfoxide, 3,5-hexadienyl phenyl sulfoxide, 3-ethylidene-4-hexenyl octyl sulfoxide, 1,8-bis(methyl sulfinyl)-3,5-octadiene, 6-(2-methyl sulfinyl-1-ethyl)-1,3-cyclo hexadiene, 6-(2-methyl sulfinyl-1-ethyl)-1,3-cyclo heptadiene, 7-(methyl sulfinyl methyl) cholesta-3,5-diene, 1-amino-3,5-heptadiene, 1,8-diamino-3,5-octadiene, 1-amino-4,6-dodecadiene, di-methyl amino-3-methylene-4-hexene, 1,4-bis(2-di-methyl amino-1-ethyl)-1-3-cyclononadiene, 1-(2-piperidino-1-ethyl)-1,3-cyclononadiene, 1,3-decadiene, 1,3-cyclononadiene, 1-(8-octa-2,4-dienyl)- 1,3-cyclononadiene, 2,4-hexadien-1-ol, 3,5-octadien-1,8-diol, 3-ethylene-4-hexene-1-ol, 3-(1-hydroxy-2-ethyl)-1,3-dihydroxy-3,5-octadiene, 2,9-dihydroxy-4,6-decadiene, 2,3-bis(1-hydroxy-2-ethyl)-1,3-cycloheptadiene, Δ 1 (2),8 -6-hexalol, 1,6-diethoxy-2,4-hexadiene, 4-(2-ethoxy-1-ethyl)-3,5-heptadien-1-ol, 3,5-octadien-1,8-dioic acid, 4-(2-propenyl)-nona-1,9-dioic acid, 2-methyl-5,7-nonadienoic acid, 9-hydroxy-4,6-nonadienoic acid, or 2-(1-carboxy-3-propyl)-3-3-(1-hydroxy-2-ethyl)-1,3-cyclohexadiene, in a skin compatible vehicle containing from about 0.1% to about 10%, by weight, surfactant wherein the surfactant is a nonionic, cationic, or amphoteric surfactant or from about 0.01% to about 0.5%, by weight, of a non-soap anionic surfactant.

Claim 6

non-soap anionic surfactant. 2. A composition adapted for topical application and capable of inhibiting chronic damage to skin induced by ultraviolet radiation in the range of 2,950 A to 4000 A, comprising an effective ultraviolet absorbing amount from about 0.001% to about 25%, by weight of 3,5-hexadienyl octyl sulfoxide, 3,5-hexadienyl phenyl sulfoxide, 3-ethylidene-4-hexenyl octyl sulfoxide, 1,8-bis(methyl sulfinyl)-3,5-octadiene, 6-(2-methyl sulfinyl-1-ethyl)-1,3-cyclo hexadiene, 6-(2-methyl sulfinyl-1-ethyl)-1,3-cyclo heptadiene, 7-(methyl sulfinyl methyl) cholesta-3,5-diene, 1-amino-3,5-heptadiene, 1,8-diamino-3,5-octadiene, 1-amino-4,6-dodecadiene, di-methyl amino-3-methylene-4-hexene, 1,4-bis(2-di-methyl amino-1-ethyl)-1-3-cyclononadiene, 1-(2-piperidino-1-ethyl)-1,3-cyclononadiene, 1,3-decadiene, 1,3-cyclononadiene, 1-(8-octa-2,4-dienyl)- 1,3-cyclononadiene, 2,4-hexadien-1-ol, 3,5-octadien-1,8-diol, 3-ethylene-4-hexene-1-ol, 3-(1-hydroxy-2-ethyl)-1,3-dihydroxy-3,5-octadiene, 2,9-dihydroxy-4,6-decadiene, 2,3-bis(1-hydroxy-2-ethyl)-1,3-cycloheptadiene, Δ 1 (2),8 -6-hexalol, 1,6-diethoxy-2,4-hexadiene, 4-(2-ethoxy-1-ethyl)-3,5-heptadien-1-ol, 3,5-octadien-1,8-dioic acid, 4-(2-propenyl)-nona-1,9-dioic acid, 2-methyl-5,7-nonadienoic acid, 9-hydroxy-4,6-nonadienoic acid, or 2-(1-carboxy-3-propyl)-3-3-(1-hydroxy-2-ethyl)-1,3-cyclohexadiene, in a skin compatible vehicle containing from about 0.1% to about 10%, by weight, surfactant wherein the surfactant is a nonionic, cationic, or amphoteric surfactant or from about 0.01% to about 0.5%, by weight, of a non-soap anionic surfactant.