Patent US4098816A successfully refreshed from Google Patents.
US4098816A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Polycyclic oxy-aromatic acid
Assignee: Beecham Group PLC
•
Filing: 1976-01-09
•
Granted: 1978-07-04
•
Expires: 1996-01-09
Abstract
Abstract Pharmaceutical compositions having hypolipidaemic and/or hypoglycaemic activity, contain a substituted (4-carboxyphenoxy) phenyl alkane derivative.
Inventors
- 👤 David Edward Thorne
- 👤 Keith Howard Baggaley
- 👤 Brian Morgan
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 09:57
CPC Classifications
C; C07; C07C; C07C205/00; C07C205/27; C07C205/35; C07C43/00; C07C43/02; C07C43/20; C07C43/205; C07C45/00; C07C45/27; C07C45/29; C07C45/298; C07C45/61; C07C45/67; C07C45/68; C07C45/70; C07C45/71; C07C47/00; C07C47/52; C07C47/575; C07C49/00; C07C49/76; C07C49/84; C07D; C07D317/00; C07D317/08; C07D317/10; C07D317/14; C07D317/18; C07D317/24
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
75 words
A compound of the formula: ##STR34## wherein R 1 is carboxylic acid or a pharmaceutically acceptable salt thereof converted in the human body to a carboxylic acid group; R 2 is hydrogen; R 3 is hydrogen, halogen, lower alkyl or lower alkoxyl; R 4 is hydrogen, halogen, phenyl, lower alkyl, lower alkoxyl, halo-lower alkyl or nitro; q is zero or an integer from 1 to 12; and s is an integer from 2 to 6.
Claim 2
Dependent Claim
75 words
A compound of the formula: ##STR34## wherein R 1 is carboxylic acid or a pharmaceutically acceptable salt thereof converted in the human body to a carboxylic acid group; R 2 is hydrogen; R 3 is hydrogen, halogen, lower alkyl or lower alkoxyl; R 4 is hydrogen, halogen, phenyl, lower alkyl, lower alkoxyl, halo-lower alkyl or nitro; q is zero or an integer from 1 to 12; and s is an integer from 2 to 6.
Claim 3
Dependent Claim
80 words
A compound of the formula: ##STR35## wherein R 1 is carboxylic acid or a pharmaceutically acceptable salt thereof converted in the human body to a carboxylic acid group; R 2 is hydrogen; R 3 is hydrogen, halogen, lower alkyl of lower alkoxyl; R 4 is hydrogen, halogen, phenyl, lower alkyl, lower alkoxyl, halo-lower alkyl or nitro; q is zero or an integer from 1 to 12; x is an integer from 1 to 6; and Y is oxygen or sulphur.
Claim 4
Dependent Claim
80 words
A compound of the formula: ##STR35## wherein R 1 is carboxylic acid or a pharmaceutically acceptable salt thereof converted in the human body to a carboxylic acid group; R 2 is hydrogen; R 3 is hydrogen, halogen, lower alkyl of lower alkoxyl; R 4 is hydrogen, halogen, phenyl, lower alkyl, lower alkoxyl, halo-lower alkyl or nitro; q is zero or an integer from 1 to 12; x is an integer from 1 to 6; and Y is oxygen or sulphur.
Claim 5
Dependent Claim
18 words
A compound according to claim 2 wherein q is 0, R 2 is hydrogen and Y is oxygen.
Claim 6
Dependent Claim
10 words
A compound according to claim 2 wherein x is 6.
Claim 7
Dependent Claim
65 words
A compound of the formula: ##STR36## wherein R 1 is carboxylic acid or a pharmaceutically acceptable salt thereof converted in the human body to a carboxylic acid group; R 2 is hydrogen; R 3 is hydrogen, halogen, lower alkyl or lower alkoxyl; R 4 is hydrogen, halogen, phenyl, lower alkyl, lower alkoxyl, halo-lower alkyl or nitro; and y is an integer from 1 to 12.
Claim 8
Dependent Claim
65 words
A compound of the formula: ##STR36## wherein R 1 is carboxylic acid or a pharmaceutically acceptable salt thereof converted in the human body to a carboxylic acid group; R 2 is hydrogen; R 3 is hydrogen, halogen, lower alkyl or lower alkoxyl; R 4 is hydrogen, halogen, phenyl, lower alkyl, lower alkoxyl, halo-lower alkyl or nitro; and y is an integer from 1 to 12.
Claim 9
Dependent Claim
50 words
A compound of the formula: ##STR37## wherein R 1 is carboxylic acid or a pharmaceutically acceptable salt thereof converted in the human body to a carboxylic acid group; R 2 is hydrogen; R 3 is hydrogen; R 4 is lower alkoxyl; and y is an integer from 1 to 12.
Claim 10
Dependent Claim
50 words
A compound of the formula: ##STR37## wherein R 1 is carboxylic acid or a pharmaceutically acceptable salt thereof converted in the human body to a carboxylic acid group; R 2 is hydrogen; R 3 is hydrogen; R 4 is lower alkoxyl; and y is an integer from 1 to 12.
Claim 11
Dependent Claim
19 words
A compound of the formula: ##STR38## wherein R is hydrogen and R 4 ' is fluorine, bromine, or 4-methyl.
Claim 12
Dependent Claim
19 words
A compound of the formula: ##STR38## wherein R is hydrogen and R 4 ' is fluorine, bromine, or 4-methyl.
Claim 13
Dependent Claim
10 words
The compound according to claim 1 which is 4-carboxyphenoxy-phenyl methane.
Claim 14
Dependent Claim
10 words
The compound according to claim 1 which is 2-methoxy-4-carboxyphenoxy-phenyl methane.
Claim 15
Dependent Claim
10 words
The compound according to claim 1 which is 4-carboxyphenoxy-(3',4'-dichlorophenyl) methane.
Claim 16
Dependent Claim
10 words
The compound according to claim 1 which is 4-carboxyphenoxy-(4'-methylphenyl) methane.
Claim 17
Dependent Claim
12 words
The compound according to claim 1 which is sodium 4-carboxyphenoxy phenyl methane.
Claim 18
Dependent Claim
12 words
The compound according to claim 1 which is potassium 4-carboxyphenoxy phenyl methane.
Claim 19
Dependent Claim
12 words
The compound according to claim 1 which is calcium 4-carboxyphenoxy phenyl methane.
Claim 20
Dependent Claim
10 words
The compound according to claim 1 which is 4-carboxyphenoxy-(2'-methoxyphenyl) methane.
Claim 21
Dependent Claim
10 words
The compound according to claim 1 which is 4-carboxyphenoxy-(4'-fluorophenyl) methane.
References Cited (Backward Citations)
US2375138A
Cited
US2552269A
Cited
US3609167A
Cited
US3385863A
Cited
US3562331A
Cited
US3642882A
Cited
US3728383A
Cited
US3652645A
Cited
US3652645B1
Cited
US3600437A
Cited
US3764702A
Cited
US3706792A
Cited
US3956399A
Cited
US3954442A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-07-03 | 1982-01-02 | 1982-07-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-07-03 | 1986-01-02 | 1986-07-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-07-03 | 1990-01-02 | 1990-07-04 | $7700.00 | Window Closed / Lapsed |