US4098816A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Polycyclic oxy-aromatic acid
Assignee: Beecham Group PLC
•
Filing: 1976-01-09
•
Granted: 1978-07-04
•
Expires: 1996-01-09
Abstract
Abstract Pharmaceutical compositions having hypolipidaemic and/or hypoglycaemic activity, contain a substituted (4-carboxyphenoxy) phenyl alkane derivative.
Inventors
- 👤 David Edward Thorne
- 👤 Keith Howard Baggaley
- 👤 Brian Morgan
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 07:59
CPC Classifications
C; C07; C07C; C07C205/00; C07C205/27; C07C205/35; C07C43/00; C07C43/02; C07C43/20; C07C43/205; C07C45/00; C07C45/27; C07C45/29; C07C45/298; C07C45/61; C07C45/67; C07C45/68; C07C45/70; C07C45/71; C07C47/00; C07C47/52; C07C47/575; C07C49/00; C07C49/76; C07C49/84; C07D; C07D317/00; C07D317/08; C07D317/10; C07D317/14; C07D317/18; C07D317/24
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
75 words
A compound of the formula: ##STR34## wherein R 1 is carboxylic acid or a pharmaceutically acceptable salt thereof converted in the human body to a carboxylic acid group; R 2 is hydrogen; R 3 is hydrogen, halogen, lower alkyl or lower alkoxyl; R 4 is hydrogen, halogen, phenyl, lower alkyl, lower alkoxyl, halo-lower alkyl or nitro; q is zero or an integer from 1 to 12; and s is an integer from 2 to 6.
Claim 2
Dependent Claim
75 words
A compound of the formula: ##STR34## wherein R 1 is carboxylic acid or a pharmaceutically acceptable salt thereof converted in the human body to a carboxylic acid group; R 2 is hydrogen; R 3 is hydrogen, halogen, lower alkyl or lower alkoxyl; R 4 is hydrogen, halogen, phenyl, lower alkyl, lower alkoxyl, halo-lower alkyl or nitro; q is zero or an integer from 1 to 12; and s is an integer from 2 to 6.
Claim 3
Dependent Claim
80 words
A compound of the formula: ##STR35## wherein R 1 is carboxylic acid or a pharmaceutically acceptable salt thereof converted in the human body to a carboxylic acid group; R 2 is hydrogen; R 3 is hydrogen, halogen, lower alkyl of lower alkoxyl; R 4 is hydrogen, halogen, phenyl, lower alkyl, lower alkoxyl, halo-lower alkyl or nitro; q is zero or an integer from 1 to 12; x is an integer from 1 to 6; and Y is oxygen or sulphur.
Claim 4
Dependent Claim
80 words
A compound of the formula: ##STR35## wherein R 1 is carboxylic acid or a pharmaceutically acceptable salt thereof converted in the human body to a carboxylic acid group; R 2 is hydrogen; R 3 is hydrogen, halogen, lower alkyl of lower alkoxyl; R 4 is hydrogen, halogen, phenyl, lower alkyl, lower alkoxyl, halo-lower alkyl or nitro; q is zero or an integer from 1 to 12; x is an integer from 1 to 6; and Y is oxygen or sulphur.
Claim 5
Dependent Claim
18 words
A compound according to claim 2 wherein q is 0, R 2 is hydrogen and Y is oxygen.
Claim 6
Dependent Claim
10 words
A compound according to claim 2 wherein x is 6.
Claim 7
Dependent Claim
65 words
A compound of the formula: ##STR36## wherein R 1 is carboxylic acid or a pharmaceutically acceptable salt thereof converted in the human body to a carboxylic acid group; R 2 is hydrogen; R 3 is hydrogen, halogen, lower alkyl or lower alkoxyl; R 4 is hydrogen, halogen, phenyl, lower alkyl, lower alkoxyl, halo-lower alkyl or nitro; and y is an integer from 1 to 12.
Claim 8
Dependent Claim
65 words
A compound of the formula: ##STR36## wherein R 1 is carboxylic acid or a pharmaceutically acceptable salt thereof converted in the human body to a carboxylic acid group; R 2 is hydrogen; R 3 is hydrogen, halogen, lower alkyl or lower alkoxyl; R 4 is hydrogen, halogen, phenyl, lower alkyl, lower alkoxyl, halo-lower alkyl or nitro; and y is an integer from 1 to 12.
Claim 9
Dependent Claim
50 words
A compound of the formula: ##STR37## wherein R 1 is carboxylic acid or a pharmaceutically acceptable salt thereof converted in the human body to a carboxylic acid group; R 2 is hydrogen; R 3 is hydrogen; R 4 is lower alkoxyl; and y is an integer from 1 to 12.
Claim 10
Dependent Claim
50 words
A compound of the formula: ##STR37## wherein R 1 is carboxylic acid or a pharmaceutically acceptable salt thereof converted in the human body to a carboxylic acid group; R 2 is hydrogen; R 3 is hydrogen; R 4 is lower alkoxyl; and y is an integer from 1 to 12.
Claim 11
Dependent Claim
19 words
A compound of the formula: ##STR38## wherein R is hydrogen and R 4 ' is fluorine, bromine, or 4-methyl.
Claim 12
Dependent Claim
19 words
A compound of the formula: ##STR38## wherein R is hydrogen and R 4 ' is fluorine, bromine, or 4-methyl.
Claim 13
Dependent Claim
10 words
The compound according to claim 1 which is 4-carboxyphenoxy-phenyl methane.
Claim 14
Dependent Claim
10 words
The compound according to claim 1 which is 2-methoxy-4-carboxyphenoxy-phenyl methane.
Claim 15
Dependent Claim
10 words
The compound according to claim 1 which is 4-carboxyphenoxy-(3',4'-dichlorophenyl) methane.
Claim 16
Dependent Claim
10 words
The compound according to claim 1 which is 4-carboxyphenoxy-(4'-methylphenyl) methane.
Claim 17
Dependent Claim
12 words
The compound according to claim 1 which is sodium 4-carboxyphenoxy phenyl methane.
Claim 18
Dependent Claim
12 words
The compound according to claim 1 which is potassium 4-carboxyphenoxy phenyl methane.
Claim 19
Dependent Claim
12 words
The compound according to claim 1 which is calcium 4-carboxyphenoxy phenyl methane.
Claim 20
Dependent Claim
10 words
The compound according to claim 1 which is 4-carboxyphenoxy-(2'-methoxyphenyl) methane.
Claim 21
Dependent Claim
10 words
The compound according to claim 1 which is 4-carboxyphenoxy-(4'-fluorophenyl) methane.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-07-03 | 1982-01-02 | 1982-07-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-07-03 | 1986-01-02 | 1986-07-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-07-03 | 1990-01-02 | 1990-07-04 | $7700.00 | Window Closed / Lapsed |