US4091802A — Vented liquid collection device

Claim 1

Independent Claim 213 words

In a device for collecting and separating blood serum and including a collection and separation compartment defined by opposed side walls extending between two opposed ends, one of said ends being closed by blood inlet means capable of penetration by a cannula, said side walls being spaced apart adjacent to each of said ends by a distance sufficient to allow noncapillary flow of blood along said side walls, and a thixotropic gel phase separator adjacent the other of said ends, said separator being movable in said compartment and adapted for sealing across said compartment the zone of phase separation between serum and blood cells when the blood is centrifuged in said compartment; the improvement wherein said compartment side walls converge at a portion between said ends to form a neck which is reduced in a dimension transverse to fluid flow therethrough in an amount sufficient to induce capillary flow of blood through the neck, and said device further includes means defining an overflow storage compartment located adjacent to said collection and separation compartment, said compartments being fluidly connected at said other end by an overflow passageway, said passageway including means cooperable with said phase separator for terminating flow therethrough at the time the serum is separated from blood cells by the phase separator.

Claim 2

Dependent Claim 213 words

In a device for collecting and separating blood serum and including a collection and separation compartment defined by opposed side walls extending between two opposed ends, one of said ends being closed by blood inlet means capable of penetration by a cannula, said side walls being spaced apart adjacent to each of said ends by a distance sufficient to allow noncapillary flow of blood along said side walls, and a thixotropic gel phase separator adjacent the other of said ends, said separator being movable in said compartment and adapted for sealing across said compartment the zone of phase separation between serum and blood cells when the blood is centrifuged in said compartment; the improvement wherein said compartment side walls converge at a portion between said ends to form a neck which is reduced in a dimension transverse to fluid flow therethrough in an amount sufficient to induce capillary flow of blood through the neck, and said device further includes means defining an overflow storage compartment located adjacent to said collection and separation compartment, said compartments being fluidly connected at said other end by an overflow passageway, said passageway including means cooperable with said phase separator for terminating flow therethrough at the time the serum is separated from blood cells by the phase separator.

Claim 3

Dependent Claim 31 words

The improved device as defined in claim 1 wherein said flow-terminating means include a constricted portion in said passageway of a dimension which blocks flow of said gel separator during centrifugation.

Claim 4

Dependent Claim 22 words

The improved device as defined in claim 2 wherein said constricted portion has a transverse dimension no greater than about 0.30 mm.

Claim 5

Dependent Claim 42 words

The improved device as defined in claim 1, and further including means defining a dispensing compartment adjacent said other end and having an outlet aperture and valve means for controlling flow of serum from said collection and separation compartment to said aperture.

Claim 6

Independent Claim 131 words

A device for collecting and separating blood serum, comprising means defining a collection and separation compartment having two opposed ends, one of said ends comprising blood inlet means capable of penetration by a cannula; a phase separator adjacent the other of said ends, said separator being movable in said compartment and adapted for sealing across said compartment the zone of phase separation between serum and blood cells when blood is centrifuged in the compartment; and means defining a storage compartment at least partially surrounding said collection and separation compartment for receiving excess blood which flows out of said collection and separation compartment, and passage means for fluidly connecting said compartments proximate one of said ends; said storage compartment having a vent aperture extending directly to the exterior surface of the device.

Claim 7

Independent Claim 131 words

A device for collecting and separating blood serum, comprising means defining a collection and separation compartment having two opposed ends, one of said ends comprising blood inlet means capable of penetration by a cannula; a phase separator adjacent the other of said ends, said separator being movable in said compartment and adapted for sealing across said compartment the zone of phase separation between serum and blood cells when blood is centrifuged in the compartment; and means defining a storage compartment at least partially surrounding said collection and separation compartment for receiving excess blood which flows out of said collection and separation compartment, and passage means for fluidly connecting said compartments proximate one of said ends; said storage compartment having a vent aperture extending directly to the exterior surface of the device.

Claim 8

Dependent Claim 31 words

The device as defined in claim 5 wherein said passageway is constructed for cooperation with said separator to terminate flow therethrough at the time the serum is separated from blood cells.

Claim 9

Dependent Claim 66 words

The device as defined in claim 6 wherein said passageway includes a constricted orifice and a shoulder adjacent said orifice of sharply increasing flow dimensions, said constricted orifice having a transverse dimension, with respect to the direction of fluid flow, which is sufficiently small to form, in cooperation with said shoulder, a meniscus in blood located in said passageway orifice which resists flow past said shoulder.

Claim 10

Dependent Claim 38 words

The device as defined in claim 7 wherein said phase separator is a thixotropic gel and wherein said transverse dimension is no larger than about 0.30 mm, whereby said gel during centrifugation is blocked at said passageway neck.

Claim 11

Independent Claim 193 words

A device for collecting and separating blood serum, comprising means defining a collection and separation compartment having two opposed ends, one of said ends being closed and including blood inlet means capable of penetration by a cannula, said compartment further including side walls which converge at a portion between said ends to form a neck which is reduced in a dimension transverse to the direction of fluid flow therethrough in an amount sufficient to cause capillary flow of blood through the compartment neck, said compartment neck being sufficiently spaced from both of said ends to allow blood deposited at said neck by a cannula to flow towards each of said ends; means defining a vent passageway extending from said compartment to the atmosphere; a phase separator adjacent the other of said ends, said separator being movable in said compartment and adapted for sealing across said compartment the zone of phase separation between serum and blood cells when blood is centrifuged in the compartment; and means defining a storage compartment located adjacent and in fluid communication with said collection and separation compartment for enclosing and collecting excess blood from said collection and separation compartment.

Claim 12

Independent Claim 193 words

A device for collecting and separating blood serum, comprising means defining a collection and separation compartment having two opposed ends, one of said ends being closed and including blood inlet means capable of penetration by a cannula, said compartment further including side walls which converge at a portion between said ends to form a neck which is reduced in a dimension transverse to the direction of fluid flow therethrough in an amount sufficient to cause capillary flow of blood through the compartment neck, said compartment neck being sufficiently spaced from both of said ends to allow blood deposited at said neck by a cannula to flow towards each of said ends; means defining a vent passageway extending from said compartment to the atmosphere; a phase separator adjacent the other of said ends, said separator being movable in said compartment and adapted for sealing across said compartment the zone of phase separation between serum and blood cells when blood is centrifuged in the compartment; and means defining a storage compartment located adjacent and in fluid communication with said collection and separation compartment for enclosing and collecting excess blood from said collection and separation compartment.

Claim 13

Dependent Claim 201 words

A liquid collection device comprising an elongated collection compartment defined by opposed side walls extending between two opposed ends, one of said ends being closed and including blood inlet means capable of penetration by a cannula, said side walls being spaced apart adjacent to each of said ends by a distance sufficient to preclude capillary flow and converging at a portion between said ends to form a neck which is reduced in a dimension transverse to the direction of fluid flow therethrough in an amount sufficient to induce capillary flow of blood through the neck, said neck being sufficiently spaced from both of said ends as to cause blood flowing into said neck to flow towards each of said ends, means defining a vent passageway extending from said compartment to the atmosphere; and means defining an overflow passageway extending from one of said compartment ends, said passageway including a constricted orifice and a shoulder adjacent said orifice of sharply increasing flow dimensions said constricted orifice having a dimension transverse to the direction of fluid flow that is sufficiently small to form, in cooperation with said shoulder, a meniscus in blood located in said passageway orifice which resists flow past said shoulder.

Claim 14

Dependent Claim 201 words

A liquid collection device comprising an elongated collection compartment defined by opposed side walls extending between two opposed ends, one of said ends being closed and including blood inlet means capable of penetration by a cannula, said side walls being spaced apart adjacent to each of said ends by a distance sufficient to preclude capillary flow and converging at a portion between said ends to form a neck which is reduced in a dimension transverse to the direction of fluid flow therethrough in an amount sufficient to induce capillary flow of blood through the neck, said neck being sufficiently spaced from both of said ends as to cause blood flowing into said neck to flow towards each of said ends, means defining a vent passageway extending from said compartment to the atmosphere; and means defining an overflow passageway extending from one of said compartment ends, said passageway including a constricted orifice and a shoulder adjacent said orifice of sharply increasing flow dimensions said constricted orifice having a dimension transverse to the direction of fluid flow that is sufficiently small to form, in cooperation with said shoulder, a meniscus in blood located in said passageway orifice which resists flow past said shoulder.

Claim 15

Dependent Claim 52 words

The device as defined in claim 10, and further including a phase separator movable in said compartment and adapted for sealing across said compartment the zone of phase separation between serum and blood cells when the blood is centrifuged within the compartment whereby said compartment functions also as a serum separation compartment.

Claim 16

Dependent Claim 21 words

The device as defined in claim 11 wherein said transverse dimension of said orifice blocks flow of said gel during centrifugation.

Claim 17

Dependent Claim 158 words

A liquid collection device comprising wall means defining two generally elongated compartments concentrically positioned one about the other; said wall means also defining a control passageway connecting said compartments and comprising a constricted orifice and a shoulder adjacent to the orifice of sharply increased flow dimensions, said constricted orifice having a dimension transverse to the direction of fluid flow that is sufficiently small as to induce, in cooperation with said shoulder, the formation of a meniscus in blood which resists flow past said shoulder, the inner one of said compartments having blood inlet means capable of penetration by a cannula, said wall means further defining a vent aperture extending from the compartment to the exterior of the device, means defining a dispensing chamber located adjacent to said compartments and having an outlet aperture, and valve means for controlling flow of liquid from one of said compartments to said aperture, whereby said device also functions to dispense the liquid.

Claim 18

Dependent Claim 158 words

A liquid collection device comprising wall means defining two generally elongated compartments concentrically positioned one about the other; said wall means also defining a control passageway connecting said compartments and comprising a constricted orifice and a shoulder adjacent to the orifice of sharply increased flow dimensions, said constricted orifice having a dimension transverse to the direction of fluid flow that is sufficiently small as to induce, in cooperation with said shoulder, the formation of a meniscus in blood which resists flow past said shoulder, the inner one of said compartments having blood inlet means capable of penetration by a cannula, said wall means further defining a vent aperture extending from the compartment to the exterior of the device, means defining a dispensing chamber located adjacent to said compartments and having an outlet aperture, and valve means for controlling flow of liquid from one of said compartments to said aperture, whereby said device also functions to dispense the liquid.

Claim 19

Dependent Claim 36 words

The device as defined in claim 13 wherein said aperture has an axis sufficiently inclined to the flow of liquid in said outermost compartment as to prevent flow of the liquid out of the vent aperture.

Claim 20

Dependent Claim 35 words

The device as defined in claim 13 wherein the innermost compartment is defined by side walls which converge at a portion between the ends of the compartment to form a neck of reduced transverse dimension.

Claim 21

Dependent Claim 97 words

A liquid collection device comprising wall means defining two generally elongated compartments concentrically disposed one about the other, one of said compartments having blood inlet means capable of penetration by a cannula, and means defining a passageway fluidly connecting said compartments, said innermost compartment including opposed side walls extending between two opposed ends, said side walls being spaced apart adjacent to each of said ends by a distance greater than about 0.4 cm, said side walls converging at a portion intermediate said ends to form a neck having a transverse dimension no greater than about 0.4 cm.

Claim 22

Dependent Claim 97 words

A liquid collection device comprising wall means defining two generally elongated compartments concentrically disposed one about the other, one of said compartments having blood inlet means capable of penetration by a cannula, and means defining a passageway fluidly connecting said compartments, said innermost compartment including opposed side walls extending between two opposed ends, said side walls being spaced apart adjacent to each of said ends by a distance greater than about 0.4 cm, said side walls converging at a portion intermediate said ends to form a neck having a transverse dimension no greater than about 0.4 cm.

Claim 23

Dependent Claim 112 words

A vented liquid collection and dispensing device, comprising means defining a collection compartment, including an intake end permitting liquid intake, a discharge end opposite to said intake end, and at least one capillary passageway disposed between said ends, means defining a dispensing compartment adjacent said discharge end, means defining a vent passageway extending from a point adjacent to said discharge end to the exterior of said device, means for displacing liquid from said collection compartment into said dispensing compartment, and for sealing off said vent passageway, in response to a centrifugal force, said displacing and said sealing means being movably supported within said device and initially disposed adjacent to said discharge end.

Claim 24

Dependent Claim 112 words

A vented liquid collection and dispensing device, comprising means defining a collection compartment, including an intake end permitting liquid intake, a discharge end opposite to said intake end, and at least one capillary passageway disposed between said ends, means defining a dispensing compartment adjacent said discharge end, means defining a vent passageway extending from a point adjacent to said discharge end to the exterior of said device, means for displacing liquid from said collection compartment into said dispensing compartment, and for sealing off said vent passageway, in response to a centrifugal force, said displacing and said sealing means being movably supported within said device and initially disposed adjacent to said discharge end.

Claim 25

Dependent Claim 25 words

The device as defined in claim 17 wherein said displacing means and said sealing means comprise a thixotropic gel initially positioned within said dispensing compartment.

Annuity Stage	Window Opens	Payment Deadline	Surcharge Period Until	Estimated Fee	Status
3.5 Years (Year 4)	1981-05-29	1981-11-28	1982-05-30	$2000.00	Window Closed / Lapsed
7.5 Years (Year 8)	1985-05-29	1985-11-28	1986-05-30	$3760.00	Window Closed / Lapsed
11.5 Years (Year 12)	1989-05-29	1989-11-28	1990-05-30	$7700.00	Window Closed / Lapsed

Vented liquid collection device

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