US3645252A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Apparatus for sampling blood or the like fluid
Assignee: Gilford Instrument Laboratories Inc
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Filing: 1968-12-05
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Granted: 1972-02-29
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Expires: 1988-12-05
Abstract
Abstract An elongate vessel having a blind end and an open end has a plurality of lengths of capillary tubing mounted on its interior in a removable assembly, the lengths being parallel to one another and axially arranged relative to the vessel. One end of each length of tubing is closed off and the other end is open. All of the lengths of tubing are mounted in a header that is disposed adjacent the open end of the vessel, the open ends of the lengths of tubing being in communication with the chamber formed in the vessel between the header and the open end, the open end being provided with a closure that includes a diaphragm capable of being pierced by a cannula without leakage. On assembly and closing of the vessel, at least the end chamber is evacuated thereby also evacuating the interior of each of the lengths of capillary tubing. The interior chamber may also be evacuated to prolong storage life, in which case there is a bleed passageway between the two chambers which preferably is capable of being blocked when the apparatus is ready for use. At that time or subsequently the interior chamber may be connected to atmosphere to enable facile withdrawal of the header with the filled lengths of tubing. A valve arrangement provides for the connecting of the chambers, their being disconnected one from the other and the connecting of the interior chamber with the atmosphere. In use, the closure end is inserted into the socket of a cylindrical receptacle that has a double-ended needle cannula in its end wall, the exterior end being pierced into the blood vessel of a patient. When the collecting vessel is pushed home into the receptacle, the interior end of the cannula pierces the diaphragm, the vacuum in the end chamber and capillary tubing lengths draws blood into said end chamber and lengths, after which the entire apparatus is removed from the patient''s blood vessel. A plurality of capillary tube lengths can thus be filled at bedside quickly and conveniently and thus be ready for centrifugation and further processing. The header preferably is secured to the closure of the collecting vessel so that after the lengths of tubing are filled with the sample fluid, the separation of the closure from the remainder of the closed collecting vessel carries all of the lengths of tubing with it, thus rendering them easily handled thereafter. Where the interior chamber has been connected to atmosphere, the closure is easily removed with a minimum of effort.
Inventors
- 👤 Saul R Gilford
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 13:44
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/15; A61B5/150007; A61B5/150015; A61B5/15003; A61B5/150206; A61B5/150213; A61B5/150221; A61B5/150251; A61B5/150351; A61B5/150374; A61B5/150381; A61B5/150389; A61B5/150473; A61B5/150496; A61B5/150503; A61B5/150511; A61B5/153; A61B5/154; A61B5/155; A61B5/150259
Claims Analysis
Total Claims: 36
Claim 1
Independent Claim
137 words
Apparatus for obtaining multiple samples of blood or the like fluid, which comprises: A. a closed-end evacuatable vessel having an open end provided with a closure and the vessel capable of holding a pressure less than atmospheric pressure and having i. an assembly of lengths of capillary tubing mounted therein, each length having a closed end and an open end, ii. a fluid receiving end chamber formed interior of said vessel adjacent the closure thereof, and said lengths each having its open end in communication with said end chamber, and B. means for connecting said end chamber to a source of fluid through said closure of said vessel, whereby when said connection is established, a quantity of said fluid will be drawn from said source into said end chamber and thence into said lengths of capillary tubing.
Claim 2
Dependent Claim
137 words
Apparatus for obtaining multiple samples of blood or the like fluid, which comprises: A. a closed-end evacuatable vessel having an open end provided with a closure and the vessel capable of holding a pressure less than atmospheric pressure and having i. an assembly of lengths of capillary tubing mounted therein, each length having a closed end and an open end, ii. a fluid receiving end chamber formed interior of said vessel adjacent the closure thereof, and said lengths each having its open end in communication with said end chamber, and B. means for connecting said end chamber to a source of fluid through said closure of said vessel, whereby when said connection is established, a quantity of said fluid will be drawn from said source into said end chamber and thence into said lengths of capillary tubing.
Claim 3
Dependent Claim
29 words
The apparatus as claimed in claim 1 in which said closure comprises a flexible diaphragm and said means for connecting includes a sharp-ended cannula adapted to pierce said diaphragm.
Claim 4
Dependent Claim
47 words
The apparatus as claimed in claim 2 in which means are provided for mounting said cannula with its sharp end in position to pierce said diaphragm, said mounting means including structure to guide movement of said vessel to bring said diaphragm into engagement with said sharp end.
Claim 5
Dependent Claim
76 words
The apparatus as claimed in claim 3 in which said vessel is of substantially elongate cylindrical configuration and the mounting means and structure for guiding comprise a generally hollow cylindrical member of internal diameter larger than the outer diameter of said closed-end vessel, having an open end into which said vessel may be introduced telescopically, and a closed end with said cannula mounted coaxially therein with its sharp end on the interior of said cylindrical member.
Claim 6
Independent Claim
23 words
The apparatus as claimed in claim in which said cannula includes a second sharp end on the exterior of said hollow cylindrical member.
Claim 7
Dependent Claim
183 words
Apparatus for obtaining multiple samples of blood or the like fluid, which comprises: A. a closed-end vessel having an open end provided with a closure and the vessel adapted to be evacuated and having i. an assembly of lengths of capillary tubing mounted therein, each length having a closed end and an open end, ii. a fluid receiving end chamber formed in said vessel adjacent the closure thereof, and said lengths each having its open end in communication with said end chamber, and B. means for connecting said end chamber to a source of fluid through said closure of said vessel, whereby when said connection is established, a quantity of said fluid will be drawn from said source into said end chamber and thence into said lengths of capillary tubing and said assembly includes a header adjacent said closure and spaced therefrom to separate substantially the larger portion of said vessel from said closure, and the said end chamber is formed between said closure and said header while an interior chamber is formed between said header and the closed end of the vessel.
Claim 8
Dependent Claim
183 words
Apparatus for obtaining multiple samples of blood or the like fluid, which comprises: A. a closed-end vessel having an open end provided with a closure and the vessel adapted to be evacuated and having i. an assembly of lengths of capillary tubing mounted therein, each length having a closed end and an open end, ii. a fluid receiving end chamber formed in said vessel adjacent the closure thereof, and said lengths each having its open end in communication with said end chamber, and B. means for connecting said end chamber to a source of fluid through said closure of said vessel, whereby when said connection is established, a quantity of said fluid will be drawn from said source into said end chamber and thence into said lengths of capillary tubing and said assembly includes a header adjacent said closure and spaced therefrom to separate substantially the larger portion of said vessel from said closure, and the said end chamber is formed between said closure and said header while an interior chamber is formed between said header and the closed end of the vessel.
Claim 9
Dependent Claim
51 words
The apparatus as claimed in claim 6 in which said closure comprises a flexible pierceable diaphragm and said means for connecting includes a hollow sharp member capable of piercing said diaphragm whereby liquid may be introduced into said end chamber by a pressure differential at opposite ends of said sharp member.
Claim 10
Dependent Claim
40 words
The apparatus as claimed in claim 6 in which each of said lengths of capillary tubing has at least that portion adjacent its open end removably engaged in said header with said open end in communication with said end chamber.
Claim 11
Dependent Claim
25 words
The apparatus as claimed in claim 6 in which an equalizing passageway is provided through said header connecting said end chamber with said interior chamber.
Claim 12
Dependent Claim
31 words
The apparatus as claimed in claim 9 in which valve means are provided to enable the equalizing passageway to be selectively closed or opened without removing said closure from said vessel.
Claim 13
Dependent Claim
127 words
The apparatus as claimed in claim 10 in which said valve means comprise an elongate needlelike member having an exterior end on the exterior of the said closure, extending through the closure and having an interior end of the interior chamber, a lateral passageway from the end chamber to the elongate needlelike member, at least a portion of the needlelike member having a hollow bore from the intersection of said lateral passageway to its exterior end, a port in the needlelike member at said intersection, and said equalizing passageway comprising said lateral passageway, port and the hollow bore from said port to said interior end, said needlelike member being slidable by manipulation of said exterior end to move said port out of alignment with said lateral passageway.
Claim 14
Dependent Claim
41 words
The apparatus as claimed in claim 11 in which said hollow bore extends the entire length of said needlelike member and a removable cap is provided at said exterior end whereby removal of said cap connects said bore with the atmosphere.
Claim 15
Dependent Claim
27 words
Apparatus as claimed in claim 11 in which there is an enlargement on the said exterior end to limit movement of said needlelike member into said closure.
Claim 16
Dependent Claim
92 words
Apparatus as claimed in claim 11 in which said needlelike member has a second hollow bore at its upper end blocked from said first hollow bore but open to the atmosphere, a second port communicating with said second hollow bore but not with said lateral passageway, and the length of the needlelike member being suCh that it can be moved a sufficient distance into the closure to bring said second part into said interior chamber whereby to connect said interior chamber to atmosphere through said second port and the second hollow bore.
Claim 17
Dependent Claim
20 words
Apparatus as claimed in claim 10 in which said valve means enable selective connection of said interior chamber to atmosphere.
Claim 18
Dependent Claim
114 words
Apparatus as claimed in claim 15 in which said valve means comprise two needlelike members extending into said closure, one needlelike member having a hollow bore at the bottom thereof and the other needlelike member having a hollow bore at the top thereof, each needlelike member having a port connected to its bore, the port of the said one needlelike member being in communication with said end chamber while its bore communicates with said interior chamber and adapted to be moved blocking its port, the other needlelike member having its port blocked while the bore is connected to atmosphere but adapted to be moved to bring the port into communication with said interior chamber.
Claim 19
Dependent Claim
47 words
Apparatus as claimed in claim 16 in which said needlelike members have portions of different length protruding out of said closure and said means for connecting includes a pusher movable against the closure in an axial movement to move said portions into said closure at different times.
Claim 20
Dependent Claim
20 words
The apparatus as claimed in claim 17 in which one needlelike member has a longer protruding portion than the other.
Claim 21
Dependent Claim
93 words
The apparatus as claimed in claim 18 in which said pusher comprises a cylindrical member having a cannula in one end wall with one sharp end on the exterior of said end wall and a second sharp end on the interior of said end wall, and adapted to be engaged on the interior of said cylindrical member so that the second sharp end may pierce said closure while the first end is piercing a source of blood or the like fluid, said end wall adapted to come into engagement with said protruding lengths.
Claim 22
Dependent Claim
36 words
The apparatus as claimed in claim 8 in which said header supports each of said lengths at the open end thereof and means are provided in said vessel for supporting the closed ends of said lengths.
Claim 23
Dependent Claim
24 words
The apparatus as claimed in claim 1 in which said closed-end vessel is formed of a transparent tubular body portion having a blind end.
Claim 24
Dependent Claim
47 words
The apparatus as claimed in claim 1 in which said assembly comprises a pair of spaced-apart plugs, each length of capillary tubing being secured to both plugs and all being arranged substantially parallel to one another, and said plugs being telescopically and removably engaged with said vessel.
Claim 25
Dependent Claim
162 words
A sampling device for use with a cylindrical member having a cannula in one end wall thereof with one sharp end on the exterior of said end wall and a second sharp end on the interior of said end wall, and adapted to be engaged on the interior of said cylindrical member so that the second sharp end piece may pierce said sampling device while the first sharp end is piercing a source of blood or the like fluid, said sampling device comprising: A. an enclosed evacuatable vessel and having a pierceable end, B. a partition in said vessel adjacent to but spaced interior from said pierceable end to form a fluid accumulating chamber thereat, C. a plurality of lengths of capillary tubing disposed on the interior of said vessel and extending through said partition, i. each length having an open end on the side of said partition forming said chamber and a closed end on the opposite side of said partition.
Claim 26
Dependent Claim
162 words
A sampling device for use with a cylindrical member having a cannula in one end wall thereof with one sharp end on the exterior of said end wall and a second sharp end on the interior of said end wall, and adapted to be engaged on the interior of said cylindrical member so that the second sharp end piece may pierce said sampling device while the first sharp end is piercing a source of blood or the like fluid, said sampling device comprising: A. an enclosed evacuatable vessel and having a pierceable end, B. a partition in said vessel adjacent to but spaced interior from said pierceable end to form a fluid accumulating chamber thereat, C. a plurality of lengths of capillary tubing disposed on the interior of said vessel and extending through said partition, i. each length having an open end on the side of said partition forming said chamber and a closed end on the opposite side of said partition.
Claim 27
Dependent Claim
18 words
The sampling device as claimed in claim 23 in which there is an equalizing passageway through said partition.
Claim 28
Dependent Claim
31 words
The sampling device as claimed in claim 23 in which said partition is removable from said vessel so that all of said lengths of tubing may be installed or removed together.
Claim 29
Dependent Claim
33 words
The sampling device as claimed in claim 23 in which there is a second partition in said vessel spaced from the first partition and supporting all of the closed ends of said lengths.
Claim 30
Dependent Claim
19 words
The sampling device as claimed in claim 24 in which means are provided selectively to block said equalizing passageway.
Claim 31
Dependent Claim
21 words
The sampling device as claimed in claim 27 in which said blocking means include the end wall of said cylindrical member.
Claim 32
Dependent Claim
103 words
A sampling device comprising: A. an enclosed evacuated vessel having an end wall normally blocking admission to said vessel but capable of being unblocked to permit introduction of liquid into said vessel therethrough, B. a partition in said vessel adjacent to but having at least a portion thereof spaced from said end wall to form a fluid receiving and distributing chamber between said partition and wall, C. a plurality of lengths of capillary tubing disposed on the interior of said vessel supported by said partition and each having an open end communicating through said partition with said chamber and a closed opposite end.
Claim 33
Dependent Claim
103 words
A sampling device comprising: A. an enclosed evacuated vessel having an end wall normally blocking admission to said vessel but capable of being unblocked to permit introduction of liquid into said vessel therethrough, B. a partition in said vessel adjacent to but having at least a portion thereof spaced from said end wall to form a fluid receiving and distributing chamber between said partition and wall, C. a plurality of lengths of capillary tubing disposed on the interior of said vessel supported by said partition and each having an open end communicating through said partition with said chamber and a closed opposite end.
Claim 34
Dependent Claim
27 words
The device of claim 29 in which the vessel has a closure, the end wall is on said closure and the partition is secured to said closure.
Claim 35
Dependent Claim
37 words
The device as claimed in claim 29 in which the larger portion of the volume of said vessel is on the side of said partition opposite said chamber and there is an equalizing passageway through said partition.
Claim 36
Dependent Claim
18 words
The device as claimed in claim 31 in which means are provided selectively to block said equalizing passageway.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-02-28 | 1975-08-30 | 1976-02-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-02-28 | 1979-08-30 | 1980-02-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-02-28 | 1983-08-30 | 1984-02-29 | $7700.00 | Window Closed / Lapsed |