Patent US4087538A successfully refreshed from Google Patents.
US4087538A
Expired / Lapsed
US
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Ophthalmic suspensions
Assignee: Merck and Co Inc
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Filing: 1976-09-09
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Granted: 1978-05-02
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Expires: 1996-09-09
Abstract
Abstract Improved anti-inflammatory suspensions for ophthalmic applications, comprising 1-(p-chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl acetic acid as active ingredient.
Inventors
- 👤 Joel B. Portnoff
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 13:42
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/40; A61K31/403; A61K31/404; A61K31/405; A61K9/00; A61K9/0012; A61K9/0048
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
58 words
An ophthalmic suspension composition comprising 10 mg./ml. of total suspension of a medicament composition comprising 1-(p-chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl acetic acid; 0.375 to 1.5 mg./ml. of total suspension of a deflocculating agent comprising polyoxyethylene (20) sorbitan monooleate; 5.0 to 15.0 mg./ml. of total suspension of a flocculating agent comprising benzyl alcohol and β-phenylethyl alcohol in a 1:1 weight ratio; and water.
Claim 2
Dependent Claim
58 words
An ophthalmic suspension composition comprising 10 mg./ml. of total suspension of a medicament composition comprising 1-(p-chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl acetic acid; 0.375 to 1.5 mg./ml. of total suspension of a deflocculating agent comprising polyoxyethylene (20) sorbitan monooleate; 5.0 to 15.0 mg./ml. of total suspension of a flocculating agent comprising benzyl alcohol and β-phenylethyl alcohol in a 1:1 weight ratio; and water.
Claim 3
Dependent Claim
26 words
The composition of claim 1 wherein there is present a viscosity inducing agent, a preservative, an anti-oxidant, a chelating agent, a humectant and an autoclaving aid.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-05-01 | 1981-10-31 | 1982-05-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-05-01 | 1985-10-31 | 1986-05-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-05-01 | 1989-10-31 | 1990-05-02 | $7700.00 | Window Closed / Lapsed |