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US4087519A Expired / Lapsed US ⏱️ 0.0 years remaining

Medicament for the treatment of hepatitis and/or acute or chronic infections due to the virus of hepatitis B

Assignee: Institut Merieux SA
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Filing: 1976-12-20
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Granted: 1978-05-02
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Expires: 1996-12-20
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Abstract

Abstract This invention relates to a medicament which contains a gamma-globulin preparation containing anti-e antibodies. This medicament can be used for eliminating or reducing the infectiousness of biological liquids containing antigen-e or the virus of hepatitis B and can also be administered intramuscularly or intravenously to treat hepatitis and/or acute or chronic infections caused by the virus of hepatitis B in humans and animals.

Inventors

  • 👤 Christian G. Trepo

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-04 11:43
CPC Classifications
C; C07; C07K; C07K16/00; C07K16/08; C07K16/081; C07K16/082; A; A61; A61P; A61P31/00; A61P31/12; A61K; A61K38/00; Y; Y10; Y10S; Y10S530/00; Y10S530/827; Y10S530/829; Y10S530/83; Y10S530/85; Y10S530/851

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 55 words
A medicament which contains, in a physiologically acceptable medium, a gamma-globulin preparation containing an effective amount of anti-e antibodies, the said preparation being obtained from serum or blood plasma or from placentary extracts and the said preparation being free from substantially all normal blood protein constituents other than gamma-globulins and from substantially all infectious contaminants.
Claim 2
Dependent Claim 55 words
A medicament which contains, in a physiologically acceptable medium, a gamma-globulin preparation containing an effective amount of anti-e antibodies, the said preparation being obtained from serum or blood plasma or from placentary extracts and the said preparation being free from substantially all normal blood protein constituents other than gamma-globulins and from substantially all infectious contaminants.
Claim 3
Dependent Claim 24 words
A medicament according to claim 1 in which the gamma-globulin preparation has been subjected to a treatment to eliminate or reduce its anticomplementary power.
Claim 4
Dependent Claim 26 words
A medicament according to claim 2, which consists of blood, of plasma or of any other biological liquid to which the gamma-globulin preparation has been added.
Claim 5
Dependent Claim 19 words
A medicament according to claim 1 in which the said gamma-globulin preparation contains predominantly one of the anti-e antibodies.
Claim 6
Dependent Claim 20 words
A medicament according to claim 4, in which the said gamma-globulin preparation contains predominantly anti-e 1 or anti-e 2 antibodies.
Claim 7
Dependent Claim 35 words
A process for the treatment of hepatitis or acute or chronic infections caused by the virus of hepatitis B comprising administering intramuscularly or intravenously to an infected human or animal the medicament of claim 1.
Claim 8
Dependent Claim 72 words
A process for eliminating or reducing the infectiousness of a biological liquid which contains the virus of hepatitis B or antigen-e comprising contacting said liquid with a gamma-globulin preparation containing an effective amount of anti-e antibodies, the said preparation being obtained from serum or blood plasma or from placentary extracts and the said preparation being free from substantially all normal blood protein constituents other than gamma-globulins and from substantially all infectious contaminants.
Claim 9
Dependent Claim 72 words
A process for eliminating or reducing the infectiousness of a biological liquid which contains the virus of hepatitis B or antigen-e comprising contacting said liquid with a gamma-globulin preparation containing an effective amount of anti-e antibodies, the said preparation being obtained from serum or blood plasma or from placentary extracts and the said preparation being free from substantially all normal blood protein constituents other than gamma-globulins and from substantially all infectious contaminants.
Claim 10
Dependent Claim 21 words
A process according to claim 7, in which the said gamma-globulin preparation containing anti-e antibodies is added to the said liquid.
Claim 11
Dependent Claim 25 words
A process according to claim 7 in which the said liquid is passed over an immuno-adsorbent, the surface of which is lined with anti-e antibodies.

References Cited (Backward Citations)

US3830909A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1981-05-01 1981-10-31 1982-05-02 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1985-05-01 1985-10-31 1986-05-02 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1989-05-01 1989-10-31 1990-05-02 $7700.00 Window Closed / Lapsed

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