Patent US4087447A successfully refreshed from Google Patents.
US4087447A
Expired / Lapsed
US
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Anti-secretory prostaglandins intermediates
Assignee: GD Searle LLC
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Filing: 1977-02-22
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Granted: 1978-05-02
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Expires: 1997-02-22
Abstract
Abstract The present invention encompasses novel intermediates of the formula: ##STR1## wherein R is phenyl, cyclohexyl or lower alkyl having 1-6 carbon atoms; R' is trialkylsilyl wherein the alkyls have 1-4 carbon atoms, tetrahydropyran-2-yl, or tetrahydrofuran-2-yl; and R" is lower alkyl having 1 to 3 carbon atoms. Compounds of the present invention are useful in synthesizing prostaglandin-like molecules which are active anti-secretory agents.
Inventors
- 👤 Paul W. Collins
- 👤 Raphael Pappo
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 10:27
CPC Classifications
C; C07; C07C; C07C405/00; C07F; C07F7/00; C07F7/02; C07F7/08; C07F7/18; C07F7/1804; C07F7/22; C07F7/2208
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
18 words
A compound of the formula: wherein R is lower alkyl having 1-6 carbon atoms and R' is trialkylsilyl
Claim 2
Dependent Claim
18 words
A compound of the formula: wherein R is lower alkyl having 1-6 carbon atoms and R' is trialkylsilyl
Claim 3
Dependent Claim
8 words
A compound according to claim 1 which is
Claim 4
Dependent Claim
9 words
A compound according to claim 1 which is 4-methyl-4(RS)-triethylsilyloxy
Claim 5
Dependent Claim
12 words
A compound according to claim 1 which is 4-methyl-4(RS)-trimethylsilyloxy oct-trans-1-enyl tri n-hexyltin.
References Cited (Backward Citations)
US4038308A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-05-01 | 1981-10-31 | 1982-05-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-05-01 | 1985-10-31 | 1986-05-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-05-01 | 1989-10-31 | 1990-05-02 | $7700.00 | Window Closed / Lapsed |