Patent US4087444A successfully refreshed from Google Patents.
US4087444A
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Amides as ovulation inhibitors
Assignee: Eli Lilly and Co
•
Filing: 1976-09-08
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Granted: 1978-05-02
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Expires: 1996-09-08
Abstract
Abstract N-[2-(5-methoxy-6-haloindol-3-yl)ethyl]amides are valuable, orally active, ovulation inhibitors.
Inventors
- 👤 Michael E. Flaugh
- 👤 James A. Clemens
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 19:45
CPC Classifications
C; C07; C07D; C07D209/00; C07D209/02; C07D209/04; C07D209/08; C07C; C07C205/00; C07C205/13; C07C205/26; C07C207/00; C07C207/04; C07D209/10; C07D209/12; C07D209/14; C07D209/16; C07D209/18
Claims Analysis
Total Claims: 26
Claim 1
Independent Claim
65 words
A compound of the formula ##STR9## in which R is hydrogen, C 1 -C 4 alkyl, phenyl, or phenyl substituted with halo, C 1 -C 4 alkyl, or C 1 -C 4 alkoxy; R 1 is hydrogen or C 1 -C 4 alkyl; R 2 is hydrogen, haloacetyl, C 1 -C 5 alkanoyl, benzoyl, or benzoyl substituted with halo or methyl; and X is halogen.
Claim 2
Dependent Claim
65 words
A compound of the formula ##STR9## in which R is hydrogen, C 1 -C 4 alkyl, phenyl, or phenyl substituted with halo, C 1 -C 4 alkyl, or C 1 -C 4 alkoxy; R 1 is hydrogen or C 1 -C 4 alkyl; R 2 is hydrogen, haloacetyl, C 1 -C 5 alkanoyl, benzoyl, or benzoyl substituted with halo or methyl; and X is halogen.
Claim 3
Dependent Claim
10 words
Compound of claim 1, in which R 2 is hydrogen.
Claim 4
Dependent Claim
11 words
Compound of claim 2, in which R is hydrogen or methyl.
Claim 5
Dependent Claim
9 words
Compound of claim 3, in which R is hydrogen.
Claim 6
Dependent Claim
10 words
Compound of claim 2, in which R 1 is hydrogen.
Claim 7
Dependent Claim
14 words
Compound of claim 2, in which R 1 is C 1 -C 4 alkyl.
Claim 8
Dependent Claim
10 words
Compound of claim 6, in which R 1 is methyl.
Claim 9
Dependent Claim
10 words
Compound of claim 6, in which R 1 is ethyl.
Claim 10
Dependent Claim
9 words
Compound of claim 2, in which X is chloro.
Claim 11
Dependent Claim
9 words
Compound of claim 2, in which X is fluoro.
Claim 12
Dependent Claim
23 words
Compound of claim 1, in which R 2 is halo-acetyl, C 1 -C 5 alkanoyl, benzoyl, or benzoyl substituted with halo or methyl.
Claim 13
Dependent Claim
11 words
Compound of claim 11, in which R is hydrogen or methyl.
Claim 14
Dependent Claim
9 words
Compound of claim 12, in which R is hydrogen.
Claim 15
Dependent Claim
10 words
Compound of claim 11, in which R 1 is hydrogen.
Claim 16
Dependent Claim
14 words
Compound of claim 11, in which R 1 is C 1 -C 4 alkyl.
Claim 17
Dependent Claim
10 words
Compound of claim 15, in which R 1 is methyl.
Claim 18
Dependent Claim
10 words
Compound of claim 15, in which R 1 is ethyl.
Claim 19
Dependent Claim
9 words
Compound of claim 11, in which X is chloro.
Claim 20
Dependent Claim
9 words
Compound of claim 11, in which X is fluoro.
Claim 21
Dependent Claim
10 words
Compound of claim 18, in which R 2 is acetyl.
Claim 22
Dependent Claim
10 words
Compound of claim 18, in which R 2 is pivaloyl.
Claim 23
Dependent Claim
10 words
Compound of claim 18, in which R 2 is benzoyl.
Claim 24
Dependent Claim
10 words
Compound of claim 18, in which R 2 is 4-chlorobenzoyl.
Claim 25
Dependent Claim
10 words
Compound of claim 18, in which R 2 is 2-methylbenzoyl.
Claim 26
Dependent Claim
12 words
Compound of claim 18, in which R 2 is 2,6-dimethylbenzoyl or 2,4,6-trimethylbenzoyl.
References Cited (Backward Citations)
US3925382A
Cited
SU445661A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-05-01 | 1981-10-31 | 1982-05-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-05-01 | 1985-10-31 | 1986-05-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-05-01 | 1989-10-31 | 1990-05-02 | $7700.00 | Window Closed / Lapsed |