Patent US4076737A successfully refreshed from Google Patents.
US4076737A
Expired / Lapsed
US
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Aldehydes of the pregnane series and derivatives thereof
Assignee: Novartis Corp
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Filing: 1976-08-26
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Granted: 1978-02-28
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Expires: 1996-08-26
Abstract
Abstract The derivatives of 1-dehydro-6α,9α-difluoro-16α-methyl-corticosterone having an aldehyde group in 21-position instead of the hydroxyl group, and derivatives of such aldehydes having a 2-chlorine atom, the corresponding hydrates, as well as their functional aldehyde derivatives, such as the acetals, display an antiinflammatory and thymolytic action. They are prepared by conventional methods.
Inventors
- 👤 Georg Anner
- 👤 Charles Meystre
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 05:43
CPC Classifications
C; C07; C07J; C07J13/00; C07J13/007; C07J7/00; C07J7/008; C07J7/009
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
28 words
A 20-acylate of the Δ 1 ,4,17(20) -16α-methyl-6α,9α-difluoro-11β,20-dihydroxy-3,21-dioxo-pregnatriene, in which the acylate group is derived from a lower aliphatic carboxylic acid having from 1 to 7 carbon atoms.
Claim 2
Dependent Claim
28 words
A 20-acylate of the Δ 1 ,4,17(20) -16α-methyl-6α,9α-difluoro-11β,20-dihydroxy-3,21-dioxo-pregnatriene, in which the acylate group is derived from a lower aliphatic carboxylic acid having from 1 to 7 carbon atoms.
Claim 3
Dependent Claim
18 words
A compound as claimed in claim 1, which is the 20-acetate of the Δ 1 ,4,17(20) -16α-methyl-6α,9α-difluoro-11β, 20-dihydroxy-3,21-dioxo-pregnatriene.
Claim 4
Dependent Claim
29 words
A 20-acylate of the Δ 1 ,4,17(20) -2-chloro-6α,9α-difluoro-16α-methyl- 11β,20-dihydroxy-3,21-dioxo-pregnatriene, in which the acylate group is derived from a lower aliphatic carboxylic acid having from 1 to 7 carbon atoms.
Claim 5
Dependent Claim
29 words
A 20-acylate of the Δ 1 ,4,17(20) -2-chloro-6α,9α-difluoro-16α-methyl- 11β,20-dihydroxy-3,21-dioxo-pregnatriene, in which the acylate group is derived from a lower aliphatic carboxylic acid having from 1 to 7 carbon atoms.
Claim 6
Dependent Claim
17 words
A compound as claimed in claim 3, which is the 20-acetate of the Δ 1 ,4,17(20) -2-chloro-6α,9α-difluoro-16α-methyl-11β,20-dihydroxy-3,21-dioxo-pregnatriene.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-02-27 | 1981-08-29 | 1982-02-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-02-27 | 1985-08-29 | 1986-02-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-02-27 | 1989-08-29 | 1990-02-28 | $7700.00 | Window Closed / Lapsed |