US4071613A
Expired / Lapsed
US
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Stabilized alcohol solution of reducing salt formulations for use in preparing radioisotope labeled scanning agents: liver scanning technetium-99m colloid and method of preparation
Assignee: Abbott Laboratories
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Filing: 1976-02-26
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Granted: 1978-01-31
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Expires: 1996-02-26
Abstract
Abstract A stabilized alcohol solution of reducing salt formulations has been developed and applied to the development of such agents as a radiolabeled liver scanning agent comprising colloids of technetium-99m and a reducing agent selected from the group of SnCl 2 , TiCl 3 , CrCl 2 and FeCl 2 and other salts, with or without a stabilizing agent, a bone scanning agent comprising a phosphate complex and a lung scanning agent comprising macro aggregated albumin.
Inventors
- 👤 William Ward Hunter, Jr.
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 13:02
CPC Classifications
A; A61; A61K; A61K51/00; A61K51/12; A61K51/1217; A61K51/02; A61K51/025; A61K2123/00
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
27 words
An anhydrous stabilized organic solution for preparing a technetium-99m scanning agent, said solution comprising: a metal ion salt reductant for technetium and an anhydrous nonoxidizing organic solvent.
Claim 2
Dependent Claim
27 words
An anhydrous stabilized organic solution for preparing a technetium-99m scanning agent, said solution comprising: a metal ion salt reductant for technetium and an anhydrous nonoxidizing organic solvent.
Claim 3
Dependent Claim
30 words
A solution as defined in claim 1 wherein said metal ion salt reductant is selected from the group consisting of SnCl 2 , TiCl.sub. 3, CrCl.sub. 2 and FeCl.sub. 2.
Claim 4
Dependent Claim
16 words
A solution as defined in claim 2 wherein said metal ion salt reductant is SnCl.sub. 2.
Claim 5
Dependent Claim
22 words
A solution as defined in claim 1 wherein said solvent is selected from the group consisting of ethanol, ether and aliphatic alcohols.
Claim 6
Dependent Claim
13 words
A solution as set forth in claim 4 wherein said solvent is ethanol
Claim 7
Dependent Claim
23 words
An anhydrous stabilized organic solution consisting essentially of about 2 - 200 μg. of SnCl.sub. 2 and 0.1 - 2.5 ml. of ethanol.
Claim 8
Dependent Claim
23 words
An anhydrous stabilized organic solution consisting essentially of about 2 - 200 μg. of SnCl.sub. 2 and 0.1 - 2.5 ml. of ethanol.
Claim 9
Dependent Claim
15 words
A radiolabeled scanning agent comprising a colloid of technetium-99m and the solution of claim 1.
References Cited (Backward Citations)
US3875299A
Cited
US3962412A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-01-30 | 1981-08-01 | 1982-01-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-01-30 | 1985-08-01 | 1986-01-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-01-30 | 1989-08-01 | 1990-01-31 | $7700.00 | Window Closed / Lapsed |