17-Oxo-17-phenyl-prostaglandins
Abstract
Abstract The present invention relates to 17-oxo-17-phenyl-prostaglandins having the following structural formula: ##STR1## wherein A represents a grouping of the formula: ##STR2## X represents ethylene or cis-vinylene, Y represents ethylene or trans-vinylene, R 1 represents a hydrogen atom or a methyl or ethyl group, R 2 and R 3 , which may be the same or different, each represent a hydrogen or halogen atom, a trifluoromethyl group or a straight- or branched-chain alkyl group containing from 1 to 3 carbon atoms, and R 4 represents a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 12 carbon atoms and cyclodextrin clathrates of such acids and esters, and when R 4 represents a hydrogen atom, non-toxic salts thereof. These compounds exhibit characteristic prostaglandin activity, e.g., abortifacient activity, stimulation activity on uterine contraction, and so on.
Inventors
- 👤 Masaki Hayashi
- 👤 Seiji Kori
- 👤 Hajimu Miyake
- 👤 Kimiichiro Matsumoto
Bibliographic Details
Claims Analysis
Total Claims: 7References Cited (Backward Citations)
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