Patent US4070449A successfully refreshed from Google Patents.
US4070449A
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Compounds having a physiological cooling effect and compositions containing them
Assignee: Warner Lambert Co LLC
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Filing: 1973-07-20
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Granted: 1978-01-24
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Expires: 1993-07-20
Abstract
Abstract Compositions are disclosed having a physiological cooling action on the skin. The compositions contain as the active ingredient certain acyclic secondary and tertiary sulphoxides and sulphones.
Inventors
- 👤 David G. Rowsell
- 👤 Roger Hems
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 22:55
CPC Classifications
C; C07; C07C; C07C321/00; C07C321/22; A; A23; A23L; A23L27/00; A23L27/20; A23L27/202; A23L27/2022; A23L27/203; A24; A24B; A24B15/00; A24B15/18; A24B15/28; A24B15/30; A61; A61K; A61K8/00; A61K8/02; A61K8/0208; A61K8/18; A61K8/30; A61K8/46; A61Q; A61Q13/00; A61Q17/00; A61Q17/005; A61Q19/00; C07C317/00; C07C317/12; A61K2800/00; A61K2800/20; A61K2800/24; A61K2800/244; A61Q11/00; A61Q15/00; A61Q19/002; A61Q19/10; A61Q5/00; A61Q5/02; A61Q9/00; A61Q9/02; C07C2601/00; C07C2601/12; C07C2601/14
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
172 words
In a personal care product for topical application to the human body, comprising a topically administrable vehicle and, as adjuvants in said vehicle, i) an antiseptic or odourant or both, and ii) a compound capable of stimulating the cold receptors of the nervous system in the surface tissues of the body when brought into contact therewith by topical application of the said product, the improvement which comprises using as said cold receptor stimulating compound an effective amount of a cold receptor stimulating acyclic sulfoxide or sulfone of the formula: ##STR10## wherein R 1 is H or C 1 -C 5 alkyl; R 2 is C 1 -C 6 alkyl; R 3 is C 1 -C 8 alkyl; R 1 , r 2 and R 3 together provide a total of from 3- 15 carbon atoms; R 1 is C 1 -C 8 alkyl; R 1 , r 2 , r 3 and R 1 together provide a total of from 6-18 carbon atoms; and x is an integer from 1- 2 inclusive.
Claim 2
Dependent Claim
172 words
In a personal care product for topical application to the human body, comprising a topically administrable vehicle and, as adjuvants in said vehicle, i) an antiseptic or odourant or both, and ii) a compound capable of stimulating the cold receptors of the nervous system in the surface tissues of the body when brought into contact therewith by topical application of the said product, the improvement which comprises using as said cold receptor stimulating compound an effective amount of a cold receptor stimulating acyclic sulfoxide or sulfone of the formula: ##STR10## wherein R 1 is H or C 1 -C 5 alkyl; R 2 is C 1 -C 6 alkyl; R 3 is C 1 -C 8 alkyl; R 1 , r 2 and R 3 together provide a total of from 3- 15 carbon atoms; R 1 is C 1 -C 8 alkyl; R 1 , r 2 , r 3 and R 1 together provide a total of from 6-18 carbon atoms; and x is an integer from 1- 2 inclusive.
Claim 3
Dependent Claim
72 words
A product according to claim 1 wherein the cold receptor stimulant is of the formula defined in which R 1 is alkyl containing up to 8 carbon atoms, R 1 is H or C 1 -C 4 alkyl and R 2 and R 3 are each C 1 -C 6 alkyl, R 1 , R 1 , R 2 and R 3 together providing a total of from 8-14 carbon atoms inclusive.
Claim 4
Dependent Claim
38 words
A product according to claim 1, which is a toilet lotion comprising an aqueous, alcoholic or aqueous alcoholic base and, as adjuvants therein, i) an antiseptic or odourant or a mixture thereof, and ii) said cold receptor stimulant.
Claim 5
Dependent Claim
37 words
A product according to claim 1, which is a cosmetic preparation comprising an oil-in-water emulsion base, and, as adjuvants in said base, i) at least one of an antiseptic or odourant and ii) said cold receptor stimulant.
Claim 6
Dependent Claim
41 words
A product according to claim 1, which is a shaving preparation comprising a foamable base containing a soap or synthetic surfactant and, as adjuvants in said base, (i) a perfume or antiseptic or mixture thereof and (ii) said cold receptor stimulant.
Claim 7
Independent Claim
121 words
A method of stimulating the cold receptors of the nervous system of the surface tissues of the body which comprises contacting the receptors with an effective amount of a cold receptor stimulating sulfoxide or sulfone of the formula: ##STR11## wherein R 1 is H or C 1 -C 5 alkyl; R 2 is C 1 -C 6 alkyl; R 3 is C 1 -C 8 alkyl; R 1 , r 2 and R 3 together provide a total of from 3- 15 carbon atoms; R 1 is C 1 -C 8 alkyl; R 1 , r 2 , r 3 and R 1 together provide a total of from 6-18 carbon atoms; and x is an integer from 1- 2 inclusive.
Claim 8
Independent Claim
121 words
A method of stimulating the cold receptors of the nervous system of the surface tissues of the body which comprises contacting the receptors with an effective amount of a cold receptor stimulating sulfoxide or sulfone of the formula: ##STR11## wherein R 1 is H or C 1 -C 5 alkyl; R 2 is C 1 -C 6 alkyl; R 3 is C 1 -C 8 alkyl; R 1 , r 2 and R 3 together provide a total of from 3- 15 carbon atoms; R 1 is C 1 -C 8 alkyl; R 1 , r 2 , r 3 and R 1 together provide a total of from 6-18 carbon atoms; and x is an integer from 1- 2 inclusive.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-01-23 | 1981-07-25 | 1982-01-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-01-23 | 1985-07-25 | 1986-01-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-01-23 | 1989-07-25 | 1990-01-24 | $7700.00 | Window Closed / Lapsed |