Patent US4070371A successfully refreshed from Google Patents.
US4070371A
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US
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Derivatives of 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid
Assignee: Wyeth LLC
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Filing: 1976-12-13
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Granted: 1978-01-24
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Expires: 1996-12-13
Abstract
Abstract Indole derivatives characterized by having a 1,3,4,9-tetrahydropyrano[3,4-b]indole or 1,3,4,9-tetrahydrothiopyrano[3,4-b]indole nucleus bearing a substituent in position 1, said substituent incorporating an acid, ester or amide function therein, are disclosed. The nucleus is further substituted at position 1 and may be optionally substituted at positions 3, 4, 5, 6, 7, 8, and 9. The derivatives are useful antiinflammatory, analgesic, antibacterial and antifungal agents and methods for their preparation and use are also disclosed.
Inventors
- 👤 Christopher A. Demerson
- 👤 Leslie G. Humber
- 👤 Thomas A. Dobson
- 👤 Ivo L. Jirkovsky
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 08:02
CPC Classifications
C; C07; C07D; C07D405/00; C07D405/02; C07D405/04; C07D311/00; C07D311/02; C07D311/76; C07D409/00; C07D409/02; C07D409/04; C07D491/00; C07D491/02; C07D491/04; C07D491/044; C07D491/052; C07D495/00; C07D495/02; C07D495/04; H; H10; H10D; H10D10/00
Claims Analysis
Total Claims: 42
Claim 1
Independent Claim
2 words
1-Cyclopropyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 2
Dependent Claim
2 words
1-Cyclopropyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 3
Dependent Claim
2 words
1-Benzyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 4
Dependent Claim
2 words
1-Benzyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 5
Dependent Claim
2 words
1-Ethyl-6-fluoro-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 6
Dependent Claim
2 words
1-Ethyl-6-fluoro-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 7
Dependent Claim
2 words
7-Chloro-1-ethyl-4-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 8
Dependent Claim
2 words
7-Chloro-1-ethyl-4-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 9
Dependent Claim
2 words
1-Ethyl-7-fluoro-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 10
Dependent Claim
2 words
1-Ethyl-7-fluoro-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 11
Dependent Claim
2 words
8-Chloro-1-ethyl-4-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 12
Dependent Claim
2 words
8-Chloro-1-ethyl-4-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 13
Dependent Claim
2 words
1,8-Diethyl-4-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 14
Dependent Claim
2 words
1,8-Diethyl-4-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 15
Dependent Claim
2 words
1-Ethyl-8-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-actic acid.
Claim 16
Dependent Claim
2 words
1-Ethyl-8-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-actic acid.
Claim 17
Dependent Claim
2 words
1-Ethyl-8-isopropyl-1,3,4,9-tetrahydropyrano[3,4-b]indole1-acetic acid.
Claim 18
Dependent Claim
2 words
1-Ethyl-8-isopropyl-1,3,4,9-tetrahydropyrano[3,4-b]indole1-acetic acid.
Claim 19
Dependent Claim
2 words
8-Butyl-1-ethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 20
Dependent Claim
2 words
8-Butyl-1-ethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 21
Dependent Claim
2 words
8-sec-Butyl-1-ethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 22
Dependent Claim
2 words
8-sec-Butyl-1-ethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 23
Dependent Claim
2 words
1-Ethyl-8-isobutyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 24
Dependent Claim
2 words
1-Ethyl-8-isobutyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 25
Dependent Claim
2 words
8-tert-Butyl-1-ethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 26
Dependent Claim
2 words
8-tert-Butyl-1-ethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 27
Dependent Claim
2 words
1-Ethyl-4,5,8-trimethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 28
Dependent Claim
2 words
1-Ethyl-4,5,8-trimethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 29
Dependent Claim
2 words
7,8-Dichloro-1-ethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 30
Dependent Claim
2 words
7,8-Dichloro-1-ethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 31
Dependent Claim
2 words
8-Chloro-1-ethyl-7-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid
Claim 32
Dependent Claim
2 words
8-Chloro-1-ethyl-7-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid
Claim 33
Dependent Claim
2 words
7-Chloro-1-ethyl-8-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 34
Dependent Claim
2 words
7-Chloro-1-ethyl-8-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 35
Dependent Claim
2 words
1-Ethyl-7-fluoro-8-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 36
Dependent Claim
2 words
1-Ethyl-7-fluoro-8-methyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 37
Dependent Claim
2 words
8-Ethyl-1-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 38
Dependent Claim
2 words
8-Ethyl-1-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 39
Dependent Claim
2 words
1,8-Dipropyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 40
Dependent Claim
2 words
1,8-Dipropyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 41
Dependent Claim
2 words
7-Chloro-8-methyl-1-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
Claim 42
Dependent Claim
2 words
7-Chloro-8-methyl-1-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid.
References Cited (Backward Citations)
US3939178A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-01-23 | 1981-07-25 | 1982-01-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-01-23 | 1985-07-25 | 1986-01-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-01-23 | 1989-07-25 | 1990-01-24 | $7700.00 | Window Closed / Lapsed |