§
Luxuse
Patent Intelligence
Sign In
← Back to Patent Explorer
US4066678A Expired / Lapsed US ⏱️ 0.0 years remaining

3-trihydroxygermyl propionic acid and its salts and a process for the production thereof

Assignee: Individual
•
Filing: 1976-06-18
•
Granted: 1978-01-03
•
Expires: 1996-06-18
📄 Original PDF 🌐 Google Patents 🔄 Sync Now

Abstract

Abstract Novel pharmacologically important organic germanium compounds (3-hydroxygermyl propionic acid salts) represented by the formula ##STR1## WHEREIN Met is a monovalent cation selected from the group consisting of Na, K, NH 4 , and NH 2 (CH 3 ) 2 , or divalent cation selected from the group consisting of Ca and Mg, and wherein x is 1 when Met is a monovalent cation and x is 2 when Met is a divalent cation. These compounds possess valuable therapeutic properties for treating such physiological abnormalities as psychiatric and neurological disorders, metabolic disorder, cardivascular disorder, disorder of digestive organs, skin disease, allergic disease, Kidney dysfunction, hepatic dysfunction, obstetric and pediatric diseases, etc., and the process for preparing thereof.

Inventors

  • 👤 Ryuichi Sato
  • 👤 Akira Ishikawa
  • 👤 Yukihito Ishida
  • 👤 Hiroshi Sato
  • 👤 Setsuo Tomisawa
  • 👤 Shigeshi Toyoshima
  • 👤 Shiro Ikegami

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 02:05
CPC Classifications
C; C07; C07F; C07F7/00; C07F7/30; A; A61; A61P; A61P1/00; A61P1/04; A61P1/10; A61P1/16; A61P13/00; A61P13/02; A61P15/00; A61P17/00; A61P25/00; A61P25/02; A61P25/08; A61P25/18; A61P25/24; A61P25/26; A61P27/00; A61P27/02; A61P27/14; A61P3/00; A61P3/06; A61P3/08; A61P37/00; A61P37/08; A61P43/00; A61P7/00; A61P7/04; A61P7/10; A61P9/00; A61P9/12; A61P9/14

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 65 words
A compound of the formula ##STR4## wherein Met is a monovalent cation selected from the group consisting of Na, K, NH 4 , and NH 2 (CH 3 ) 2 , or a divalent cation selected from the group consisting of Ca and Mg, and wherein x is 1 when Met is a monovalent cation and x is 2 when Met is a divalent cation.
Claim 2
Dependent Claim 65 words
A compound of the formula ##STR4## wherein Met is a monovalent cation selected from the group consisting of Na, K, NH 4 , and NH 2 (CH 3 ) 2 , or a divalent cation selected from the group consisting of Ca and Mg, and wherein x is 1 when Met is a monovalent cation and x is 2 when Met is a divalent cation.
Claim 3
Dependent Claim 13 words
The compound of claim 1 wherein Met is Na and x is 1.
Claim 4
Dependent Claim 13 words
The compound of claim 1 wherein Met is Mg and x is 2.
Claim 5
Dependent Claim 13 words
The compound of claim 1 wherein Met is Ca and x is 2.
Claim 6
Dependent Claim 95 words
A process for preparing the compound of claim 1, which process comprises reacting trichlorogermanium with acrylic acid to thereby obtain 3-trichlorogermyl propionic acid of the formula ##STR5## hydrolyzing said acid with caustic alkali solution followed by acidification to thereby obtain 3-germylpropionic acid oxide of the formula (Ge--CH.sub.2 --CH.sub.2 --CO.sub.2 H).sub.2n O.sub.3n, wherein n=1, 2 or 3, and reacting said oxide with a hydroxide of the metal Met, wherein Met is the cation Na, K, NH 4 , NH 2 (CH 3 ) 2 , Ca, or Mg, to thereby form the compound of claim 6.

References Cited (Backward Citations)

US3689516A Cited
US3812167A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1981-01-02 1981-07-04 1982-01-03 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1985-01-02 1985-07-04 1986-01-03 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1989-01-02 1989-07-04 1990-01-03 $7700.00 Window Closed / Lapsed

Assigned Categories & Tags

No categories assigned to this patent yet.

Assign Category Tag