Patent US4066501A successfully refreshed from Google Patents.
US4066501A
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Method for producing l-lysine by fermentation
Assignee: Ajinomoto Co Inc
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Filing: 1977-02-22
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Granted: 1978-01-03
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Expires: 1997-02-22
Abstract
Abstract L-lysine produced by Brevibacterium or Corynebacterium mutants that are resistant to α-aminolauryllactam, γ-methyl-lysine or N.sup.ω -carbobenzoxy lysine.
Inventors
- 👤 Osamu Tosaka
- 👤 Hajimu Morioka
- 👤 Hayao Hirakawa
- 👤 Kenji Ishii
- 👤 Koji Kubota
- 👤 Yoshio Hirose
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 22:30
CPC Classifications
C; C12; C12P; C12P13/00; C12P13/04; C12P13/08; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/822; Y10S435/84; Y10S435/843; Y10S435/859; Y10S435/861
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
55 words
A method for producing L-lysine by fermentation which comprises: a. aerobically culturing in an aqueous culture medium an L-lysine producing mutant belonging to the genus Brevibacterium or Corynebacterium until L-lysine is accumulated in the culture medium, said mutant being resistant to α-amino-lauryllactam, α-methyl-lysine, or N.sup.ω -carbobenzoxy-lysine; b. recovering the accumulated L-lysine from the culture medium.
Claim 2
Independent Claim
55 words
A method for producing L-lysine by fermentation which comprises: a. aerobically culturing in an aqueous culture medium an L-lysine producing mutant belonging to the genus Brevibacterium or Corynebacterium until L-lysine is accumulated in the culture medium, said mutant being resistant to α-amino-lauryllactam, α-methyl-lysine, or N.sup.ω -carbobenzoxy-lysine; b. recovering the accumulated L-lysine from the culture medium.
Claim 3
Dependent Claim
16 words
A method as set forth in claim 1, wherein said mutant is additionally resistant to S-(2-aminoethyl)-L-cysteine.
Claim 4
Dependent Claim
16 words
A method as set forth in claim 2, wherein said mutant additionally requires L-alanine for growth.
Claim 5
Dependent Claim
53 words
A method as set forth in claim 1, wherein said mutant is: Brevibacterium lactofermentum FERM-P 3382 brevibacterium lactofermentum FERM-P 3383 brevibacterium lactofermentum FERM-P 3384 brevibacterium lactofermentum FERM-P 3385 brevibacterium lactofermentum FERM-P 3386 brevibacterium lactofermentum FERM-P 3387 (ATCC 31269) corynebacterium acetoglutamicum FERM-P 3380 (ATCC 31270) corynebacterium acetoglutamicum FERM-P 3381 or Corynebacterium acetoglutamicum FERM-P 3414.
References Cited (Backward Citations)
US3707441A
Cited
US3905867A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-01-02 | 1981-07-04 | 1982-01-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-01-02 | 1985-07-04 | 1986-01-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-01-02 | 1989-07-04 | 1990-01-03 | $7700.00 | Window Closed / Lapsed |