US4065485A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Cyclitolamines
Assignee: ER Squibb and Sons LLC
•
Filing: 1976-10-26
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Granted: 1977-12-27
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Expires: 1996-10-26
Abstract
Abstract Compounds having the structure <IMAGE> wherein R1 is alkyl or arylalkyl; R2 is -C 3BOND N, -C 3BOND CH or <IMAGE> wherein R4 is hydrogen, alkyl, aryl, or arylalkyl; R3 is alkanoyl; m is 1, 2, 3, or 4; n is 1, 2, or 3; and p is 0, 1, 2 or 3; are useful for the treatment of hypertension.
Inventors
- 👤 Frederic P. Hauck
- 👤 Joyce Reid
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 13:12
CPC Classifications
C; C07; C07C; C07C255/00; C07C255/45
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
79 words
A compound having the formula ##STR11## or a pharmaceutically acceptable acid-addition salt thereof, wherein R 1 is alkyl or arylalkyl; R 3 is alkanoyl of 1 to 7 carbon atoms; m is 1, 2, 3 or 4; n is 1, 2 or 3; and p is 0, 1, 2 or 3; wherein aryl is phenyl or phenyl substituted with one or two halogen, alkyl or alkoxy groups; and alkyl and alkoxy are groups having 1 to 6 carbon atoms.
Claim 2
Dependent Claim
79 words
A compound having the formula ##STR11## or a pharmaceutically acceptable acid-addition salt thereof, wherein R 1 is alkyl or arylalkyl; R 3 is alkanoyl of 1 to 7 carbon atoms; m is 1, 2, 3 or 4; n is 1, 2 or 3; and p is 0, 1, 2 or 3; wherein aryl is phenyl or phenyl substituted with one or two halogen, alkyl or alkoxy groups; and alkyl and alkoxy are groups having 1 to 6 carbon atoms.
Claim 3
Dependent Claim
11 words
A compound in accordance with claim 1 wherein n is 1.
Claim 4
Dependent Claim
11 words
A compound in accordance with claim 1 wherein n is 2.
Claim 5
Dependent Claim
11 words
A compound in accordance with claim 1 wherein n is 3.
Claim 6
Dependent Claim
12 words
A compound in accordance with claim 1 wherein R 1 is alkyl.
Claim 7
Dependent Claim
12 words
A compound in accordance with claim 5 wherein R 1 is methyl.
Claim 8
Dependent Claim
12 words
A compound in accordance with claim 1 wherein R 3 is acetyl.
Claim 9
Dependent Claim
21 words
A compound in accordance with claim 1 wherein m and p are the same or different and are 2 or 3.
Claim 10
Dependent Claim
30 words
A compound in accordance with claim 1 wherein R 1 is methyl, R 3 is acetyl, and m and p are the same or different and are 2 or 3.
References Cited (Backward Citations)
US3894031A
Cited
US3971823A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-12-26 | 1981-06-27 | 1981-12-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-12-26 | 1985-06-27 | 1985-12-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-12-26 | 1989-06-27 | 1989-12-27 | $7700.00 | Window Closed / Lapsed |