Patent US4772691A successfully refreshed from Google Patents.
Patent US4060640A successfully refreshed from Google Patents.
US4060640A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Therapeutic agents
Assignee: Shell USA Inc
•
Filing: 1976-06-08
•
Granted: 1977-11-29
•
Expires: 1996-06-08
Abstract
Abstract O-HALOBENZYLIDENEAMINOGUANIDINES ARE EMPLOYED AS CENTRAL NERVOUS SYSTEM DEPRESSANTS, AS CARDIOVASCULAR DEPRESSANTS, AND/OR AS ANTIDEPRESSANTS FOR OVERCOMING PSYCHIC DEPRESSION.
Inventors
- 👤 Jiro K. Kodama
- 👤 George R. Haynes
- 👤 James R. Albert
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 05:24
CPC Classifications
C; C07; C07C; C07C281/00; C07C281/16; C07C281/18
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
135 words
A method of inducing a central nervous system depressant response in mammals to reduce hyperexcitability and induce sedation which comprises administering to a mammal an effective dosage for inducing a central nervous system depressant response of a compound of the formula ##STR4## wherein X is halogen or trifluoromethyl, Y and Z may be the same or different and each is hydrogen, halogen, trifluoromethyl or alkyl of 1 to 4 carbon atoms, R, R', R" and R° each is hydrogen, alkyl of 1 to 4 carbon atoms, alkenyl of 2 to 4 carbon atoms or alkynyl of 2 to 4 carbon atoms with the proviso that R" and R° may together form an ethylene or vinylene bridge, with the further proviso that one of Y and R must be hydrogen, or a pharmaceutically acceptable salt thereof.
Claim 2
Independent Claim
135 words
A method of inducing a central nervous system depressant response in mammals to reduce hyperexcitability and induce sedation which comprises administering to a mammal an effective dosage for inducing a central nervous system depressant response of a compound of the formula ##STR4## wherein X is halogen or trifluoromethyl, Y and Z may be the same or different and each is hydrogen, halogen, trifluoromethyl or alkyl of 1 to 4 carbon atoms, R, R', R" and R° each is hydrogen, alkyl of 1 to 4 carbon atoms, alkenyl of 2 to 4 carbon atoms or alkynyl of 2 to 4 carbon atoms with the proviso that R" and R° may together form an ethylene or vinylene bridge, with the further proviso that one of Y and R must be hydrogen, or a pharmaceutically acceptable salt thereof.
Claim 3
Dependent Claim
31 words
A method according to claim 1 wherein X and Y each is chlorine, and Z, R, R', R" and R° each is hydrogen, and the salt is a hydrochloric acid salt.
Claim 4
Dependent Claim
23 words
A method according to claim 1 wherein X and Y each is chlorine, and Z, R, R', R" and R° each is hydrogen.
Claim 5
Dependent Claim
32 words
A method according to claim 1 wherein X and Y each is middle halogen and Z, R, R', R" and R° each is hydrogen, and the salt is a hydrohalic acid salt.
References Cited (Backward Citations)
GB1019120A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-11-28 | 1981-05-30 | 1981-11-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-11-28 | 1985-05-30 | 1985-11-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-11-28 | 1989-05-30 | 1989-11-29 | $7700.00 | Window Closed / Lapsed |