Patent US4058601A successfully refreshed from Google Patents.
US4058601A
Expired / Lapsed
US
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Method for treating alcoholism
Assignee: Chugai Pharmaceutical Co Ltd
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Filing: 1975-07-01
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Granted: 1977-11-15
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Expires: 1995-07-01
Abstract
Abstract A pharmaceutical composition for reducing the alcohol content or slowing the rate of increase thereof in the blood and inhibiting the accumulation of neutral lipid in the liver containing a uridine diphosphate as an effective ingredient and a method of the use thereof are disclosed.
Inventors
- 👤 Shun-ichi Hata
- 👤 Koji Mizuno
- 👤 Yasuho Nishii
- 👤 Etsuko Mitsuishi
- 👤 Motoharu Shiba
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 16:35
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; C; C07; C07H; C07H5/00; C07H5/08; C07H5/10
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
59 words
A method for reducing the alcohol content or slowing the rate of increase thereof in the blood and inhibiting the accumulation of neutral lipid in the liver of human beings, which comprises administering to human beings, orally or parenterally, a pharmaceutical composition comprising an effective amount of a uridine diphosphate as an effective ingredient and a pharmaceutically acceptable carrier.
Claim 2
Independent Claim
59 words
A method for reducing the alcohol content or slowing the rate of increase thereof in the blood and inhibiting the accumulation of neutral lipid in the liver of human beings, which comprises administering to human beings, orally or parenterally, a pharmaceutical composition comprising an effective amount of a uridine diphosphate as an effective ingredient and a pharmaceutically acceptable carrier.
Claim 3
Dependent Claim
29 words
A method as set forth in claim 1 wherein said pharmaceutical composition is administered to human beings orally in the form of tablet, granule, powder, capsule, suspension or lemonade.
Claim 4
Dependent Claim
29 words
A method as set forth in claim 1 wherein the administration of said uridine diphosphate is made orally in a dose of from 10 to 5,000 mg per dose.
Claim 5
Dependent Claim
29 words
A method as set forth in claim 1 wherein the administration of said uridine diphosphate is made orally in a dose of from 50 to 500 mg per dose.
Claim 6
Dependent Claim
29 words
A method as set forth in claim 1 wherein the administration of said uridine diphosphate is made parenterally in a dose of from 10 to 1,000 mg per dose.
Claim 7
Dependent Claim
29 words
A method as set forth in claim 1 wherein the administration of said uridine diphosphate is made parenterally in a dose of from 50 to 500 mg per dose.
Claim 8
Dependent Claim
23 words
A method as set forth in claim 1 wherein the uridine diphosphate is the free form of uridine-5'-diphosphate or a metallic salt thereof.
Claim 9
Dependent Claim
26 words
A method as set forth in claim 7 wherein said metallic salt of uridine-5'-diphosphate is selected from the group consisting of sodium, potassium and lithium salts.
Claim 10
Dependent Claim
23 words
A method as set forth in claim 1 wherein the uridine diphosphate is the free form of uridine-3'-diphosphate or a metallic salt thereof.
Claim 11
Dependent Claim
26 words
A method as set forth in claim 9 wherein said metallic salt of uridine-3'-diphosphate is selected from the group consisting of sodium, potassium and lithium salts.
Claim 12
Independent Claim
57 words
A method for slowing the rate of alcohol level increase in the blood and inhibiting the accumulation of neutral lipids in the liver, which comprises orally administering a pharmaceutical composition comprising an effective amount of uridine diphosphate as an active ingredient and a pharmaceutically acceptable carrier just before or at the time of intake of alcoholic drinks.
Claim 13
Independent Claim
57 words
A method for slowing the rate of alcohol level increase in the blood and inhibiting the accumulation of neutral lipids in the liver, which comprises orally administering a pharmaceutical composition comprising an effective amount of uridine diphosphate as an active ingredient and a pharmaceutically acceptable carrier just before or at the time of intake of alcoholic drinks.
Claim 14
Independent Claim
66 words
A method for slowing the rate of alcohol level increase in the blood and inhibiting the accumulation of neutral lipids in the liver, which comprises intravenously or intramuscularly injecting a pharmaceutical composition in the form of parenteral injection comprising an effective amount of a uridine diphosphate as an active ingredient and a pharmaceutically acceptable carrier just before or at the time of intake of alcoholic drinks.
Claim 15
Independent Claim
66 words
A method for slowing the rate of alcohol level increase in the blood and inhibiting the accumulation of neutral lipids in the liver, which comprises intravenously or intramuscularly injecting a pharmaceutical composition in the form of parenteral injection comprising an effective amount of a uridine diphosphate as an active ingredient and a pharmaceutically acceptable carrier just before or at the time of intake of alcoholic drinks.
Claim 16
Independent Claim
49 words
A method for reducing the alcohol content of the blood and the accumulation of neutral lipid in the liver, which comprises orally administering to a patient suffering from alcoholism a pharmaceutical composition comprising an effective amount of a uridine diphospate as an active ingredient and a pharmaceutically acceptable carrier.
Claim 17
Independent Claim
49 words
A method for reducing the alcohol content of the blood and the accumulation of neutral lipid in the liver, which comprises orally administering to a patient suffering from alcoholism a pharmaceutical composition comprising an effective amount of a uridine diphospate as an active ingredient and a pharmaceutically acceptable carrier.
Claim 18
Dependent Claim
36 words
A method as set forth in claim 13 wherein said pharmaceutical composition is administered several times a day, the total amount per day being a maximum of 300 mg/kg. body weight based on the active ingredient.
Claim 19
Independent Claim
64 words
A method for reducing the alcohol content of the blood and the accumulation of neutral lipid in the liver, which comprises intravenously or intramuscularly administering to a patient suffering from alcoholism a pharmaceutical composition for the prevention and treatment of alcoholism in the form of parenteral injection comprising an effective amount of a uridine diphosphate as an active ingredient and a pharmaceutically acceptable carrier.
Claim 20
Independent Claim
64 words
A method for reducing the alcohol content of the blood and the accumulation of neutral lipid in the liver, which comprises intravenously or intramuscularly administering to a patient suffering from alcoholism a pharmaceutical composition for the prevention and treatment of alcoholism in the form of parenteral injection comprising an effective amount of a uridine diphosphate as an active ingredient and a pharmaceutically acceptable carrier.
Claim 21
Dependent Claim
37 words
A method as set forth in claim 15 wherein said pharmaceutical composition is administered at several times a day the total amount per day being a maximum of 30 mg/kg. body weight based on the active ingredient.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-11-14 | 1981-05-16 | 1981-11-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-11-14 | 1985-05-16 | 1985-11-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-11-14 | 1989-05-16 | 1989-11-15 | $7700.00 | Window Closed / Lapsed |