Patent US4056611A successfully refreshed from Google Patents.
US4056611A
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Therapeutic composition
Assignee: Stiefel Laboratories Inc
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Filing: 1973-04-16
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Granted: 1977-11-01
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Expires: 1993-04-16
Abstract
Abstract The therapeutic composition is for the treatment of acne and comprises a stable dispersion of finely divided particles of benzoyl peroxide in an aqueous alcohol vehicle having a single phase, said phase being non-lipid and containing a non-ionic surface active agent that is soluble in the aqueous alcohol vehicle of the composition. The composition comprises from about 1 to 30 percent by weight benzoyl peroxide, from about 1 to 30 percent by weight of said surface active agent, from about 10 to 80 percent by weight of an alkyl alcohol having from 1 to 3 carbon atoms, and from about 10 to 80 percent by weight of water. The hydrophilic portion of the surface active agent is a polyoxyalkylene moiety wherein each oxyalkylene group contains from 2 to 3 atoms, and preferably is polyoxyethylene lauryl ether.
Inventors
- 👤 Henry Y. Young
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 01:51
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K31/00; A61K31/185; A61K31/19; A61K47/00; A61K47/06; A61K47/08; A61K47/10; A61K47/30; A61K47/36; A61K47/38; A61K8/00; A61K8/18; A61K8/30; A61K8/33; A61K8/38; A61Q; A61Q19/00; Y; Y10; Y10S; Y10S424/00; Y10S424/03
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
150 words
A therapeutic composition for the treatment of acne consisting of a stable dispersion of finely divided particles of benzoyl peroxide in an aqueous alcohol vehicle, said aqueous alcohol vehicle being a single non-lipid phase consisting essentially of a solution of water and an alkyl alcohol having from 1 to 3 carbon atoms and in which solution is dissolved a non-ionic surface active agent, the hydrophilic portion of which is a polyoxyalkylene moiety wherein each oxyalkylene group contains from 2 to 3 carbon atoms, said surface active agent being soluble in said solution, said composition containing from about 1 to 30 percent by weight benzoyl peroxide having a particle size of less than 100 microns, from about 1 to 30 percent by weight of a surface active agent, from about 10 to 80 percent by weight of said alkyl alcohol, and from about 10 to 80 percent by weight of water.
Claim 2
Dependent Claim
150 words
A therapeutic composition for the treatment of acne consisting of a stable dispersion of finely divided particles of benzoyl peroxide in an aqueous alcohol vehicle, said aqueous alcohol vehicle being a single non-lipid phase consisting essentially of a solution of water and an alkyl alcohol having from 1 to 3 carbon atoms and in which solution is dissolved a non-ionic surface active agent, the hydrophilic portion of which is a polyoxyalkylene moiety wherein each oxyalkylene group contains from 2 to 3 carbon atoms, said surface active agent being soluble in said solution, said composition containing from about 1 to 30 percent by weight benzoyl peroxide having a particle size of less than 100 microns, from about 1 to 30 percent by weight of a surface active agent, from about 10 to 80 percent by weight of said alkyl alcohol, and from about 10 to 80 percent by weight of water.
Claim 3
Dependent Claim
19 words
The composition according to claim 1 in which the hydrophilic portion of the surface active agent is polyoxyethylene moiety.
Claim 4
Dependent Claim
19 words
The composition according to claim 1 in which the hydrophilic portion of the surface active agent is polyoxypropylene moiety.
Claim 5
Dependent Claim
16 words
The composition according to claim 1 in which the surface active agent is polyoxyethylene lauryl ether.
Claim 6
Dependent Claim
37 words
The composition according to claim 1 in which the composition contains from about 0.1 to 7.5 percent by weight of a viscosity builder selected from the group consisting of natural gums, modified starch and chemically modified cellulose.
Claim 7
Dependent Claim
44 words
The composition according to claim 1 comprising essentially 5.0% by weight benzoyl peroxide, 30.0% by weight ethyl alcohol, 3.0% by weight polyoxyethylene lauryl ether, 2.5% by weight colloidal magnesium aluminum silicate, 1.5% by weight hydroxypropylmethylcellulose, 0.05% by weight citric acid and the balance water.
Claim 8
Dependent Claim
50 words
The composition according to claim 1 comprising essentially about 5% by weight benzoyl peroxide, about 40% by weight ethyl alcohol, about 6% by weight polyoxyethylene lauryl ether, about 2.5% by weight colloidal magnesium aluminum silicate, about 1.5% by weight hydroxypropylmethylcellulose, about 0.05% by weight citric acid and the balance water.
Claim 9
Dependent Claim
44 words
The composition according to claim 1 comprising essentially 10.99% by weight benzoyl peroxide, 44.10% by weight ethyl alcohol, 6.0% by weight polyoxyethylene lauryl ether, 2.5% by weight colloidal magnesium aluminum silicate, 1.0% by weight hydroxypropylmethylcellulose, 0.05% by weight citric acid and the balance water.
Claim 10
Dependent Claim
49 words
The composition according to claim 1 comprising essentially about 10% by weight benzoyl peroxide, about 40% by weight ethylalcohol, about 6% by weight polyoxyethylene lauryl ether, about 2.5% by weight colloidal magnesium aluminum silicate, about 1% by weight hydroxypropylmethylcellulose, about 0.05% by weight citric acid and the balance water.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-10-31 | 1981-05-02 | 1981-11-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-10-31 | 1985-05-02 | 1985-11-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-10-31 | 1989-05-02 | 1989-11-01 | $7700.00 | Window Closed / Lapsed |