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US4048256A
Expired / Lapsed
US
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Normally-solid, bioabsorbable, hydrolyzable, polymeric reaction product
Assignee: Wyeth Holdings LLC
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Filing: 1976-06-01
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Granted: 1977-09-13
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Expires: 1996-06-01
Abstract
Abstract A normally-solid, bioabsorbable, hydrolyzable, polymeric reaction product of (A) a polyglycolic acid composition and (B) a polyester of diglycolic acid and an unhindered glycol and to the process of preparing the same and the use of said polymeric reaction product as a sterile surgical element and as a device for the controlled continuous administration of a predetermined dosage of a drug to a living animal.
Inventors
- 👤 Donald James Casey
- 👤 Martin Epstein
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 20:28
CPC Classifications
C; C08; C08G; C08G63/00; C08G63/66; C08G63/664; A; A61; A61K; A61K9/00; A61K9/70; A61K9/7007; A61L; A61L15/00; A61L15/07; A61L15/12; A61L15/16; A61L15/42; A61L15/64; A61L17/00; A61L17/06; A61L17/10; A61L17/12; A61L17/14; A61L17/145; A61L27/00; A61L27/14; A61L27/18
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
84 words
A normally-solid, bioabsorbable, hydrolyzable, polymeric reaction product of (A) a polyglycolic acid composition and (B) a polyester of diglycolic acid and an unhindered glycol; wherein the amount of (B) used is between about 2% and 50%, by weight, based on the total weight of (A) and (B); wherein (A), before reaction with (B), has a molecular weight of at least 30,000 and (B), before reaction with (A), has a molecular weight sufficiently high so as to provide a polymeric material possessing self-supporting film-forming properties.
Claim 2
Dependent Claim
84 words
A normally-solid, bioabsorbable, hydrolyzable, polymeric reaction product of (A) a polyglycolic acid composition and (B) a polyester of diglycolic acid and an unhindered glycol; wherein the amount of (B) used is between about 2% and 50%, by weight, based on the total weight of (A) and (B); wherein (A), before reaction with (B), has a molecular weight of at least 30,000 and (B), before reaction with (A), has a molecular weight sufficiently high so as to provide a polymeric material possessing self-supporting film-forming properties.
Claim 3
Dependent Claim
19 words
A product according to claim 1 in which the reaction product of (A) and (B) is a transesterification product.
Claim 4
Dependent Claim
22 words
A polymeric reaction product according to claim 1 in which the (A) has a molecular weight of between about 50,000 and 60,000.
Claim 5
Dependent Claim
20 words
A transesterification product according to claim 2 in which (A) has a molecular weight of between about 50,000 and 60,000.
Claim 6
Dependent Claim
32 words
A polymeric reaction product according to claim 1 in which (B) is present in an amount between about 5% and 15%, by weight, based on the total weight of (A) and (B).
Claim 7
Dependent Claim
32 words
A polymeric reaction product according to claim 3 in which (B) is present in an amount between about 5% and 15%, by weight, based on the total weight of (A) and (B).
Claim 8
Dependent Claim
12 words
A self-supporting film produced from the polymeric reaction product of claim 1.
Claim 9
Dependent Claim
13 words
A flexible monofilamentary article produced from the polymeric reaction product of claim 1.
Claim 10
Dependent Claim
23 words
A normally-solid, bioabsorbable, hydroyzable polymeric reaction product according to claim 1 in which the polyglycolic acid material is a homopolymer of polyglycolic acid.
Claim 11
Dependent Claim
43 words
A normally-solid, bioabsorbable, hydrolyzable polymeric reaction product according to claim 1 in which the polyglycolic acid material is a copolymer of up to about 15 weight percent of a lactide copolymerized with at least 85 weight percent of a glycolide or glycolic acid.
Claim 12
Dependent Claim
31 words
A polymer containing glycolic acid units and alkylene diglycolate units wherein the alkylene diglycolate units are present in an amount between about 2% and 50% of the total weight of polymer.
Claim 13
Dependent Claim
31 words
A polymer containing glycolic acid units and alkylene diglycolate units wherein the alkylene diglycolate units are present in an amount between about 2% and 50% of the total weight of polymer.
Claim 14
Dependent Claim
23 words
A composition of claim 11 wherein the glycolic acid units and the alkylene diglycolate units occur in sequences of more than one unit.
Claim 15
Dependent Claim
46 words
A normally-solid, bioabsorbable, hydrolyzable polymeric reaction product of (A) a polyglycolic acid composition and (B) a polyester of diglycolic acid and a glycol; wherein the amount of (B) used is between about 2% and 50%, by weight, based on the total weight of (A) and (B).
Claim 16
Dependent Claim
46 words
A normally-solid, bioabsorbable, hydrolyzable polymeric reaction product of (A) a polyglycolic acid composition and (B) a polyester of diglycolic acid and a glycol; wherein the amount of (B) used is between about 2% and 50%, by weight, based on the total weight of (A) and (B).
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-09-12 | 1981-03-14 | 1981-09-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-09-12 | 1985-03-14 | 1985-09-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-09-12 | 1989-03-14 | 1989-09-13 | $7700.00 | Window Closed / Lapsed |