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US4048181A
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Derivatives of mercaptopyridine-1-oxide
Assignee: Colgate Palmolive Co
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Filing: 1975-11-06
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Granted: 1977-09-13
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Expires: 1995-11-06
Abstract
Abstract Novel amino derivatives of mercaptopyridine-1-oxide inclusive of 2-acylamino- and 2-alkoxycarbonylamino-6-mercaptopyridine-1-oxides, disulfides thereof, and metal salts thereof having particular utility as antimicrobial agents per se and in skin cleansing detergent compositions, shampoos, hair dressings, disinfectants, preservatives and the like.
Inventors
- 👤 Miriam Lois Douglass
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 11:52
CPC Classifications
C; C07; C07D; C07D213/00; C07D213/02; C07D213/89; A; A01; A01N; A01N43/00; A01N43/34; A01N43/40; A01N47/00; A01N47/08; A01N47/10; A01N47/18; A01N47/22; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/49; A61K8/4906; A61K8/4933; A61Q; A61Q17/00; A61Q17/005; A61Q19/00; A61Q19/10; A61K2800/00; A61K2800/40; A61K2800/52; A61K2800/524; A61Q5/00; A61Q5/02; A61Q5/06; Y; Y10; Y10S; Y10S424/00; Y10S424/04
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
135 words
A mercaptopyridine-1-oxide compound having the following structural formula: ##STR10## wherein R is selected from the group consisting of the acyl radical R o C═O and the alkoxycarbonyl radical R o -OC═O, where R o is a C 1 -C 6 alkyl, aryl selected from the class consisting of phenyl or naphthyl or aralkyl, said alkyl having portion 1-6 carbons or halobenzyl; R 1 , R 2 and R 3 are each independently selected from the group consisting of hydrogen, methyl, two of said terms may repreent methoxy and the other hydrogen, one of said terms may represent ethyl, n-butyl, methoxy, ethoxy, phenyl, bromophenyl, chlorophenyl, trichlorophenyl, naphthyl, chlorobenzyl, dichlorobenzyl or furyl and the other two terms represent hydrogen; R 4 is selected from the group consisting of hydrogen, an alkali metal, and an alkaline earth metal.
Claim 2
Dependent Claim
135 words
A mercaptopyridine-1-oxide compound having the following structural formula: ##STR10## wherein R is selected from the group consisting of the acyl radical R o C═O and the alkoxycarbonyl radical R o -OC═O, where R o is a C 1 -C 6 alkyl, aryl selected from the class consisting of phenyl or naphthyl or aralkyl, said alkyl having portion 1-6 carbons or halobenzyl; R 1 , R 2 and R 3 are each independently selected from the group consisting of hydrogen, methyl, two of said terms may repreent methoxy and the other hydrogen, one of said terms may represent ethyl, n-butyl, methoxy, ethoxy, phenyl, bromophenyl, chlorophenyl, trichlorophenyl, naphthyl, chlorobenzyl, dichlorobenzyl or furyl and the other two terms represent hydrogen; R 4 is selected from the group consisting of hydrogen, an alkali metal, and an alkaline earth metal.
Claim 3
Dependent Claim
18 words
A compound according to claim 1 wherein R 1 , R 2 and R 3 are all hydrogen.
Claim 4
Dependent Claim
22 words
A compound according to claim 2 wherein R 4 is hydrogen, and the amino substituent is the acylamino radical R 0 C═O.
Claim 5
Dependent Claim
21 words
A compound according to claim 2 wherein R 4 is hydrogen, and the amino-substituent is the alkoxycarbonyl radical R 0 --OC═O.
Claim 6
Dependent Claim
13 words
A compound according to claim 1 which is the sodium salt of 2-acylamino-6-mercaptopyridine-1-oxide.
Claim 7
Dependent Claim
1 words
2-acetamido-6-mercaptopyridine-1-oxide.
Claim 8
Dependent Claim
1 words
2-acetamido-6-mercaptopyridine-1-oxide.
Claim 9
Dependent Claim
1 words
2-ethoxy-carbonylamino-6-mercaptopyridine-1-oxide.
Claim 10
Dependent Claim
1 words
2-ethoxy-carbonylamino-6-mercaptopyridine-1-oxide.
References Cited (Backward Citations)
US3773770A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-09-12 | 1981-03-14 | 1981-09-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-09-12 | 1985-03-14 | 1985-09-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-09-12 | 1989-03-14 | 1989-09-13 | $7700.00 | Window Closed / Lapsed |