Patent US4046910A successfully refreshed from Google Patents.
US4046910A
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US
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Dosage schedule
Assignee: Pharmacia and Upjohn Co
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Filing: 1976-04-14
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Granted: 1977-09-06
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Expires: 1996-04-14
Abstract
Abstract A dosing schedule for Disodiumcromoglycate and Disodiumcromoglycate biologues whereby a substantially smaller dosage is required to bring about effective allergy inhibition. Compositions are also provided.
Inventors
- 👤 Herbert G. Johnson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 19:10
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/47; A61K31/335; A61K31/35
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
102 words
A method for administering DSCG in mammals for the prophylatic treatment of allergy of a reagin or non-reagin mediated nature which comprises a. administrating to a mammal in need of said treatment a priming dose of DSCG which provides effective inhibition of allergy manifestation, and thereafter b. administering to said mammal treated in step (a) an effective maintenance dose of DSCG, said maintenance dose quantity 1. providing greater inhibition of allergic manifestations in the maintenance dose situation than the same quantity provides in the priming dose situation and 2. being about 0.1 to about 20% of the quantity of the priming dose.
Claim 2
Independent Claim
102 words
A method for administering DSCG in mammals for the prophylatic treatment of allergy of a reagin or non-reagin mediated nature which comprises a. administrating to a mammal in need of said treatment a priming dose of DSCG which provides effective inhibition of allergy manifestation, and thereafter b. administering to said mammal treated in step (a) an effective maintenance dose of DSCG, said maintenance dose quantity 1. providing greater inhibition of allergic manifestations in the maintenance dose situation than the same quantity provides in the priming dose situation and 2. being about 0.1 to about 20% of the quantity of the priming dose.
Claim 3
Dependent Claim
30 words
A method in accordance with claim 1 wherein the maintenance dose is continued until the effect of the maintenance dose substantially lessens and thereafter repeating the priming dose-maintenance dose schedule.
Claim 4
Dependent Claim
23 words
A method in accordance with claim 1 wherein the priming dose is a quantity necessary to obtain the maximum level of allergy inhibition.
Claim 5
Dependent Claim
22 words
A method in accordance with claim 1 wherein the maintenance dose is from about 1 to about 10% of the priming dose.
Claim 6
Dependent Claim
18 words
A method in accordance with claim 1 wherein the DSCG is inhaled and the allergy treated is asthma.
Claim 7
Dependent Claim
18 words
A method in accordance with claim 4 wherein the DSCG is inhaled and the allergy treated is asthma.
Claim 8
Dependent Claim
14 words
A method in accordance with claim 5 wherein the priming dose is 20 mg.
Claim 9
Dependent Claim
14 words
A method in accordance with claim 6 wherein the priming dose is 20 mg.
References Cited (Backward Citations)
US3419578A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-09-05 | 1981-03-07 | 1981-09-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-09-05 | 1985-03-07 | 1985-09-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-09-05 | 1989-03-07 | 1989-09-06 | $7700.00 | Window Closed / Lapsed |