Pharmaceutical compositions containing 5,6,7,8-tetrahydroquinoline derivatives and related compounds

Claim 1

An anti-ulcer pharmaceutical composition comprising an effective amount of a compound of formula I ##STR11## or an acid addition salt thereof with a pharmaceutically acceptable acid, wherein R 1 , R 2 and R 6 are the same or different and are selected from hydrogen, trifluoromethyl, alkyl containing from 1 to 6 carbon atoms, phenylalkyl wherein the alkyl group has 1 - 6 carbon atoms, or phenyl groups or R 1 and R 2 taken together represent a polymethylene chain of 3 to 5 carbon atoms, R 7 represents hydrogen or from 1 to 3 groups selected from alkyl of 1 to 6 carbon atoms which may be substituted by alkoxy of 1 to 6 carbon atoms or trifluoromethyl, phenylalkyl wherein the alkyl group has 1 to 6 carbon atoms and phenyl groups, R 3 is hydrogen or alkyl of 1 to 6 carbon atoms, and any of the phenyl or the phenyl portion of any phenylalkyl groups R 1 , R 2 , R 6 and R 7 may be substituted by alkyl of 1 to 6 carbon atoms, lower alkoxy of 1 to 6 carbon atoms, halogen, nitro or trifluoromethyl with the provisos that (1) when R 1 and R 2 or R 2 and R 6 are both alkyl they are selected from normal and secondary alkyl groups and (2) when two alkyl R 7 groups are present on the same carbon atom then they are both n-alkyl groups and when two R 7 alkyl groups are present on adjacent carbon atoms they are selected from normal and secondary alkyl groups and a pharmaceutically acceptable carrier.