Patent US4425547A successfully refreshed from Google Patents.
Patent US4043344A successfully refreshed from Google Patents.
US4043344A
Expired / Lapsed
US
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Non-absorbable surgical sutures coated with polyoxyethylene-polyoxypropylene copolymer lubricant
Assignee: Wyeth Holdings LLC
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Filing: 1976-09-20
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Granted: 1977-08-23
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Expires: 1996-09-20
Abstract
Abstract The handling characteristics, including particularly the knot run down and tissue drag characteristics, of non-absorbable surgical sutures are improved by a coating of a lubricating film of a bioabsorbable copolymer having polyoxyethylene blocks and polyoxypropylene blocks, and which bioabsobable copolymer has a molecular weight such that it is pasty to solid at 25° C. This lubricant coating is absorbed in tissue in less than about 48 hours--which results in improved long term knot security.
Inventors
- 👤 Henry Patrick Landi
- 👤 Vincent Anthony Perciaccante
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 17:02
CPC Classifications
A; A61; A61L; A61L17/00; A61L17/14; A61L17/145; D; D07; D07B; D07B1/00; D07B1/14; D07B1/141; D07B1/142; C; C10; C10M; C10M2209/00; C10M2209/10; C10M2209/103; C10M2209/107; C10M2215/00; C10M2215/02; C10M2215/04; C10M2215/042; C10N; C10N2040/00; C10N2040/46; C10N2050/00; C10N2050/015; C10N2050/02; D07B2201/00; D07B2201/20; D07B2201/2083; D07B2201/209; Y; Y10; Y10T; Y10T428/00; Y10T428/29; Y10T428/2913; Y10T428/2933
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
57 words
A non-absorbable surgical suture having improved knot run-down characteristics and reduced tissue drag comprising a polyfilamentary non-absorbable strand having thereon a thin lubricating coating of a lubricating absorbable co-polymer comprising polyoxyethylene blocks and polyoxypropylene blocks to aid run-down and handleability, said bioabsorbable copolymer having a molecular weight such that it is pasty to solid at 25° C.
Claim 2
Dependent Claim
57 words
A non-absorbable surgical suture having improved knot run-down characteristics and reduced tissue drag comprising a polyfilamentary non-absorbable strand having thereon a thin lubricating coating of a lubricating absorbable co-polymer comprising polyoxyethylene blocks and polyoxypropylene blocks to aid run-down and handleability, said bioabsorbable copolymer having a molecular weight such that it is pasty to solid at 25° C.
Claim 3
Dependent Claim
91 words
The suture of claim 1 in which the lubricating bioabsorbable polymer has the formula: ##STR6## where one of R 1 and R 2 is methyl and the other hydrogen, and n and m are sufficiently large that the compound is pasty to solid at 25° C., R is the residue of a relatively low molecular weight reactive hydrogen compound having from 2 to about 6 reactive hydrogen atoms and having not over 6 carbon atoms in said compound, and c is the number of reactive hydrogens on the compound forming R.
Claim 4
Dependent Claim
36 words
The suture of claim 1 in which the lubricating bioabsorbable copolymer has effectively the formula: ##STR7## where x, y and z are sufficiently large that the lubricating bioabsorbable copolymer is pasty to solid at 25° C.
Claim 5
Dependent Claim
37 words
The suture of claim 3 in which the lubricating bioabsorbable copolymer has a moelcular weight of about 8350 and x and z are about 75 and y about 30, and the melting point is about 52° C.
Claim 6
Dependent Claim
36 words
The suture of claim 1 in which the lubricating bioabsorbable copolymer has effectively the formula: ##STR8## where n, m and o are sufficiently large that the lubricating bioabsorbable copolymer is pasty to solid at 25° C.
Claim 7
Dependent Claim
40 words
The suture of claim 1 in which the lubricating bioabsorbable copolymer has effectively the formula: ##STR9## where R 3 is ##STR10## where q and r are sufficiently large that the lubricating bioabsorbable copolymer is pasty to solid at 25° C.
Claim 8
Dependent Claim
26 words
The suture of claim 1 in which the non-absorbable strand is selected from the group consisting of silk, cotton, nylon, a non-absorbable polyester, polypropylene and polyethylene.
Claim 9
Dependent Claim
26 words
The suture of claim 3 in which the non-absorbable strand is selected from the group consisting of silk, cotton, nylon, a non-absorbable polyester, polypropylene and polyethylene.
Claim 10
Dependent Claim
26 words
The suture of claim 4 in which the non-absorbable strand is selected from the group consisting of silk, cotton, nylon, a non-absorbable polyester, polypropylene and polyethylene.
Claim 11
Dependent Claim
56 words
The suture of claim 1 in which the lubricating coating is about 0.1 to 25 percent by weight of the lubricating bioabsorbable copolymer of the weight of the uncoated strand forming the suture, whereby both chatter and friction are reduced sufficiently that a square knot is movable on the suture with control of a wound edge.
Claim 12
Dependent Claim
56 words
The suture of claim 2 in which the lubricating coating is about 0.1 to 25 percent by weight of the lubricating bioabsorbable copolymer of the weight of the uncoated strand forming the suture, whereby both chatter and fricion are reduced sufficiently that a square knot is movable on the suture with control of a wound edge.
Claim 13
Dependent Claim
56 words
The suture of claim 3 in which the lubricating coating is about 0.1 to 25 percent by weight of the lubricating bioabsorbable copolymer of the weight of the uncoated strand forming the suture, whereby both chatter and friction are reduced sufficiently that a square knot is movable on the suture with control of a wound edge.
Claim 14
Dependent Claim
56 words
The suture of claim 4 in which the lubricating coating is about 0.1 to 25 percent by weight of the lubricating bioabsorbable copolymer of the weight of the uncoated strand forming the suture, whereby both chatter and friction are reduced sufficiently that a square knot is movable on the suture with control of a wound edge.
Claim 15
Dependent Claim
56 words
The suture of claim 7 in which the lubricating coating is about 0.1 to 25 percent by weight of the lubricating bioabsorbable copolymer of the weight of the uncoated strand forming the suture, whereby both chatter and friction are reduced sufficiently that a square knot is movable on the suture with control of a wound edge.
Claim 16
Dependent Claim
56 words
The suture of claim 8 in which the lubricating coating is about 0.1 to 25 percent by weight of the lubricating bioabsorbable copolymer of the weight of the uncoated strand forming the suture, whereby both chatter and friction are reduced sufficiently that a square knot is movable on the suture with control of a wound edge.
Claim 17
Dependent Claim
56 words
The suture of claim 9 in which the lubricating coating is about 0.1 to 25 percent by weight of the lubricating bioabsorbable copolymer of the weight of the uncoated strand forming the suture, whereby both chatter and friction are reduced sufficiently that a square knot is movable on the suture with control of a wound edge.
Claim 18
Dependent Claim
93 words
A method of closing a wound in living tissue which comprises: sewing edges of a wound in living tissue with the sterile non-absorbable surgical suture of claim 1, tying the suture into a square knot, running down the square knot to approximate the tissues in a desired location, placing additional throws on the square knot, in a subcutaneous location, and within less than about 48 hours bioabsorbing and removing the lubricant absorbable coolymer from the suture thereby increasing knot security, and leaving the non-absorbable surgical suture in living tissue, thereby reinforcing the tissue.
References Cited (Backward Citations)
US3061470A
Cited
US3432898A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-08-22 | 1981-02-21 | 1981-08-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-08-22 | 1985-02-21 | 1985-08-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-08-22 | 1989-02-21 | 1989-08-23 | $7700.00 | Window Closed / Lapsed |