Patent US4042350A successfully refreshed from Google Patents.
US4042350A
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Methods and applications of preparative scale chromatography
Assignee: National Research Development Corp UK
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Filing: 1975-06-20
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Granted: 1977-08-16
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Expires: 1995-06-20
Abstract
Abstract A preparative scale chromatographic method in which a mixture is chromatographically fractionated on a sorbent material by the displacing action of a sorbate which is thermally displaced through the material by a heated zone advancing through the material to leave behind sorbent material substantially free of said sorbate. In an application of particular interest, at least one component of the mixture is produced by catalytic reaction of one or more thermally displaced sorbates induced by the heated zone of sorbent material.
Inventors
- 👤 Courtenay Stanley Goss Phillips
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 18:59
CPC Classifications
G; G01; G01N; G01N30/00; G01N30/02; G01N30/50; G01N30/52; G01N30/54; B; B01; B01D; B01D53/00; B01D53/02; B01D53/025; C; C07; C07C; C07C1/00; C07C1/26; C07C1/30; C07C17/00; C07C17/07; C07C17/087; C07C17/25; C07C5/00; C07C5/22; C07C5/2206; C07C5/2226; C07C5/2246; C07C5/23; C07C5/25; C07C5/2506; C07C5/2525; C07C5/2543; C07C5/27; C07C5/2767; C07C5/277; C07C5/2791; C07C7/00; C07C7/135; C07C2521/00; C07C2521/02; C07C2521/04; C07C2527/00; C07C2527/06; C07C2527/08; C07C2527/10; C07C2527/12; C07C2527/1206
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
125 words
A chromatographic method for fractionating a mixture of sorbate components in a continuous operation comprising: providing a flow path of sorbent having different affinities for the sorbate components of said mixture; feeding said mixture into said flow path of sorbent; and thermally displacing a sorbate through said sorbent in advance of a substantially uniform heat zone of limited width to fractionate said sorbate components into an abutting succession of components in accordance with the affinities of said components for said sorbent by relative movement between the sorbent and the heat zone, the mixture being fractionated into sorbate components in the advancing relatively cool area of sorbent ahead of said heat zone, the amount of all sorbate components falling into said heat zone being relatively insignificant.
Claim 2
Dependent Claim
125 words
A chromatographic method for fractionating a mixture of sorbate components in a continuous operation comprising: providing a flow path of sorbent having different affinities for the sorbate components of said mixture; feeding said mixture into said flow path of sorbent; and thermally displacing a sorbate through said sorbent in advance of a substantially uniform heat zone of limited width to fractionate said sorbate components into an abutting succession of components in accordance with the affinities of said components for said sorbent by relative movement between the sorbent and the heat zone, the mixture being fractionated into sorbate components in the advancing relatively cool area of sorbent ahead of said heat zone, the amount of all sorbate components falling into said heat zone being relatively insignificant.
Claim 3
Dependent Claim
18 words
A method according to claim 1 in which the thermally displaced sorbate is one component of the mixture.
Claim 4
Dependent Claim
21 words
A method according to claim 1 further comprising passing a carrier gas through the sorbent material during operation of the method.
Claim 5
Dependent Claim
22 words
A method according to claim 1 in which the sorbent material comprises charcoal and the mixture comprises a plurality of saturated hydrocarbons.
Claim 6
Dependent Claim
26 words
A method according to claim 1 in which the sorbent material comprises γ alumina and the mixture comprises a plurality of olefinically unsaturated or saturated hydrocarbons.
Claim 7
Dependent Claim
34 words
A method according to claim 1 further comprising adding a substance to the mixture to be fractionated, which substance is so chosen as to separate two components of the mixture on the sorbent material.
Claim 8
Dependent Claim
36 words
A method according to claim 1 in which the thermally displaced sorbate is unreactive and is so disposed in the displacement sequence as to separate a thermally labile sorbate in the mixture from the heated zone.
Claim 9
Dependent Claim
31 words
The chromatograhic method of claim 1 wherein the step of thermally displacing includes the step of continuously moving a plurality of spaced heat zones along the length of said flow path.
Claim 10
Dependent Claim
28 words
The chromatographic method of claim 1 wherein one of said sorbate components being displaced serves as a buffer as to at least one other sorbate component being displaced.
Claim 11
Dependent Claim
20 words
The chromatographic method of claim 9 wherein said buffer sorbate component is displaced directly ahead of said advancing heat zone.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-08-15 | 1981-02-14 | 1981-08-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-08-15 | 1985-02-14 | 1985-08-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-08-15 | 1989-02-14 | 1989-08-16 | $7700.00 | Window Closed / Lapsed |