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Antitumor derivatives of periodate-oxidized cytidine

Assignee: Wyeth LLC
•
Filing: 1976-06-21
•
Granted: 1977-08-09
•
Expires: 1996-06-21
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Abstract

Abstract The reaction of the periodate oxidation product from inosine, adenosine, or cytidine with methanol or ethanol affords a product having activity against lymphocytic leukemia P388 in mice.

Inventors

  • 👤 William Dvonch
  • 👤 Harvey E. Alburn

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 10:11
CPC Classifications
C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/06; C07H19/16

Claims Analysis

Total Claims: 4
Claim 1
Independent Claim 12 words
A compound of the formula ##STR4## wherein R is methyl or ethyl.
Claim 2
Dependent Claim 12 words
A compound of the formula ##STR4## wherein R is methyl or ethyl.
Claim 3
Dependent Claim 10 words
A compound as defined in claim 1 which is 4-amino-1-[3(5)-hydroxy-6-hydroxymethyl-5(3)-methoxy-p-dioxan-2-yl]-2H-pyrimidin-2-one.
Claim 4
Dependent Claim 10 words
A compound as defined in claim 1 which is 4-amino-1-[3(5)-ethoxy-5(3)hydroxy-6-hydroxymethyl-p-dioxan-2-yl]-2H-pyrimidin-2-one.

References Cited (Backward Citations)

US3185690A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1980-08-08 1981-02-07 1981-08-09 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1984-08-08 1985-02-07 1985-08-09 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1988-08-08 1989-02-07 1989-08-09 $7700.00 Window Closed / Lapsed

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