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US4039656A Expired / Lapsed US ⏱️ 0.0 years remaining

Production of attenuated viruses

Assignee: Bayer AG
•
Filing: 1975-01-29
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Granted: 1977-08-02
•
Expires: 1995-01-29
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Abstract

Abstract There is disclosed novel non-antigenic attenuated viruses which non-specifically stimulate the natural defense mechanism of a host organism with a detectable non-specific induction of interferon; to methods for their production and to their use for the prophylaxis and treatment of viral and bacterial infections in human and veterinary medicine. The aforesaid term "non-antigenic attenuated virus" in this application means "an attenuated virus being incapable to cause an immunological cross-reaction with the original virus".

Inventors

  • 👤 Otto-Christian Straub

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 11:21
CPC Classifications
A; A61; A61K; A61K35/00; A61K35/66; A61K35/76; C; C12; C12N; C12N2710/00; C12N2710/00011; C12N2710/16011; C12N2710/16711; C12N2710/16732; C12N2710/16761; C12N2710/16764

Claims Analysis

Total Claims: 4
Claim 1
Independent Claim 81 words
A pharmaceutical composition containing as an active ingredient attenuated IPV virus which causes no immunological cross-reaction with unattenuated IPV virus and which stimulates the natural defense mechanism of cattle with a detectable non-specific induction of interferon and which is suitable for the prophylaxis and treatment of respiratory and genital tract infections in cattle, in admixture with a pharmaceutically acceptable diluent, wherein said active ingredient is contained in an amount equivalent to 10 4 to 10 8 CiD 50 units/ml of virus.
Claim 2
Dependent Claim 81 words
A pharmaceutical composition containing as an active ingredient attenuated IPV virus which causes no immunological cross-reaction with unattenuated IPV virus and which stimulates the natural defense mechanism of cattle with a detectable non-specific induction of interferon and which is suitable for the prophylaxis and treatment of respiratory and genital tract infections in cattle, in admixture with a pharmaceutically acceptable diluent, wherein said active ingredient is contained in an amount equivalent to 10 4 to 10 8 CiD 50 units/ml of virus.
Claim 3
Dependent Claim 28 words
A pharmaceutical composition in accordance with claim 1 as a medicament in the form of one of the group consisting of tablets, pills, dragees, capsules, ampoules and suppositories.
Claim 4
Dependent Claim 19 words
A pharmaceutical composition in accordance with claim 1 in the form of a sterile isotonic or buffered aqueous solution.

References Cited (Backward Citations)

US2934473A Cited
US2941925A Cited
US3096247A Cited
US3057783A Cited
US3048524A Cited
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US3354038A Cited
US3876764A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1980-08-01 1981-01-31 1981-08-02 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1984-08-01 1985-01-31 1985-08-02 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1988-08-01 1989-01-31 1989-08-02 $7700.00 Window Closed / Lapsed

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