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US4034114A Expired / Lapsed US ⏱️ 0.0 years remaining

Treatment of skin keratoses with retinal

Assignee: Individual
•
Filing: 1976-09-15
•
Granted: 1977-07-05
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Expires: 1996-09-15
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Abstract

Abstract A treatment to alleviate the symptoms of actinic or nonactinic keratoses consisting of topical application of a solution, lotion, cream or ointment containing retinal is disclosed. The therapeutic composition may include retinal as an active ingredient present in an amount of from 0.01 to 2 percent by weight of the total composition. Topical application of the therapeutic composition in a solution, lotion, cream or ointment has been found to achieve from substantial to complete remissions of the keratoses in humans.

Inventors

  • 👤 Ruey J. Yu
  • 👤 Eugene J. Van Scott

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-05 09:23
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/11; A61K8/00; A61K8/18; A61K8/30; A61K8/67; A61K8/671; A61Q; A61Q19/00; A61Q19/004; A61K2800/00; A61K2800/74; A61K2800/75

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 50 words
A method of treating actinic or nonactinic keratoses in humans having skin affected thereby without irritating the skin comprising: administering topically to the affected skin a therapeutically effective amount of a composition comprising retinal in a pharmacologically acceptable vehicle, on a daily basis to eradicate actinic or nonactinic keratotic lesions.
Claim 2
Independent Claim 50 words
A method of treating actinic or nonactinic keratoses in humans having skin affected thereby without irritating the skin comprising: administering topically to the affected skin a therapeutically effective amount of a composition comprising retinal in a pharmacologically acceptable vehicle, on a daily basis to eradicate actinic or nonactinic keratotic lesions.
Claim 3
Dependent Claim 20 words
The method of claim 1 wherein retinal is present in from 0.01 to 2.0 percent by weight of said composition.
Claim 4
Dependent Claim 19 words
The method of claim 1 wherein retinal is present in 0.02 to 0.5 percent by weight of said composition.
Claim 5
Dependent Claim 26 words
The method of claim 1 wherein said vehicle comprises a retinal solvent selected from the group consisting of ethanol, isopropyl myristate, isopropyl palmitate, and mineral oil.
Claim 6
Dependent Claim 24 words
The method of claim 4 wherein said solvent is present in a concentration of from 5 to 50%, by volume, of the total composition.
Claim 7
Dependent Claim 24 words
The method of claim 4 wherein said solvent is present in a concentration of from 5 to 20%, by volume, of the total composition.
Claim 8
Dependent Claim 23 words
The method of claim 4 wherein said vehicle further comprises a member selected from the group consisting of water, propylene glycol, and 1,3-butanediol.
Claim 9
Dependent Claim 25 words
The method of claim 7 wherein said member is present in a concentration of no more than about 50% by volume of the total composition.

References Cited (Backward Citations)

GB902659A Cited
US3729568A Cited
US3932665A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1980-07-04 1981-01-03 1981-07-05 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1984-07-04 1985-01-03 1985-07-05 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1988-07-04 1989-01-03 1989-07-05 $7700.00 Window Closed / Lapsed

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