Patent US4026936A successfully refreshed from Google Patents.
US4026936A
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Anthelmintic pyridine and thiazole substituted benzimidazole carbamates
Assignee: Hoffmann La Roche Inc
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Filing: 1975-08-07
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Granted: 1977-05-31
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Expires: 1995-08-07
Abstract
Abstract Compounds represented by the formula <IMAGE> wherein R is <IMAGE> R1 is 2-pyridyl, 3-pyridyl, 4-pyridyl or 2-thiazyl, R2 is lower alkyl and n is 1 or 2, AND ACID ADDITION SALTS OF THE COMPOUNDS WHEREIN R1 is 2-pyridyl, 3-pyridyl or 4-pyridyl are disclosed as useful as anthelmintics against a broad spectrum of helminths. Processes for making the active compounds and novel intermediates useful therein are also disclosed.
Inventors
- 👤 Rudolph Frank Lauer
- 👤 Armin Walser
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 08:41
CPC Classifications
C; C07; C07D; C07D213/00; C07D213/02; C07D213/04; C07D213/24; C07D213/28; C07D213/30; A; A61; A61P; A61P33/00; C07D213/26; C07D213/36; C07D213/38; C07D213/44; C07D213/46; C07D213/50; C07D277/00; C07D277/02; C07D277/20; C07D277/22; C07D277/24
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
47 words
A compound represented by the formula ##STR13## wherein R is ##STR14## R 1 is 2-pyridyl, 3-pyridyl, or 4-pyridyl and R 2 is lower alkyl and n is 1 or 2, and pharmaceutically acceptable acid addition salts of the compounds wherein R 1 is 2-pyridyl, 3-pyridyl or 4-pyridyl.
Claim 2
Dependent Claim
47 words
A compound represented by the formula ##STR13## wherein R is ##STR14## R 1 is 2-pyridyl, 3-pyridyl, or 4-pyridyl and R 2 is lower alkyl and n is 1 or 2, and pharmaceutically acceptable acid addition salts of the compounds wherein R 1 is 2-pyridyl, 3-pyridyl or 4-pyridyl.
Claim 3
Dependent Claim
9 words
A compound of claim 1 wherein R is ##STR15##
Claim 4
Dependent Claim
15 words
A compound of claim 2 wherein R 1 is 2-pyridyl and R 2 is methyl.
Claim 5
Dependent Claim
15 words
A compound of claim 1 wherein R 1 is 2-pyridyl and R 2 is ethyl.
Claim 6
Dependent Claim
15 words
A compound of claim 1 wherein R 1 is 3-pyridyl and R 2 is methyl.
Claim 7
Dependent Claim
15 words
A compound of claim 1 wherein R 1 is 3-pyridyl and R 2 is ethyl.
Claim 8
Dependent Claim
15 words
A compound of claim 1 wherein R 1 is 4-pyridyl and R 2 is methyl.
Claim 9
Dependent Claim
15 words
A compound of claim 1 wherein R 1 is 4-pyridyl and R 2 is ethyl.
Claim 10
Dependent Claim
9 words
A compound of claim 1 wherein R is ##STR16##
Claim 11
Dependent Claim
15 words
A compound of claim 9 wherein R 1 is 2-pyridyl and R 2 is methyl.
Claim 12
Dependent Claim
15 words
A compound of claim 1 wherein R is --(CH 2 ) n --R 1 .
Claim 13
Dependent Claim
13 words
a compound of claim 1 wherein R is --CH 2 --R 1 .
Claim 14
Dependent Claim
15 words
A compound of claim 12 wherein R 1 is 2-pyridyl and R 2 is methyl.
References Cited (Backward Citations)
US3657267A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-05-30 | 1980-11-29 | 1981-05-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-05-30 | 1984-11-29 | 1985-05-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-05-30 | 1988-11-29 | 1989-05-31 | $7700.00 | Window Closed / Lapsed |