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US4024259A
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3-Anilino-2,4-diazabicyclo[3.2.1]octenes
Assignee: CNA Holdings LLC
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Filing: 1976-01-26
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Granted: 1977-05-17
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Expires: 1996-01-26
Abstract
Abstract Novel 3-anilino-2,4-diazabicyclo[3.2.1]octenes, physiologically tolerable acid addition salts thereof and method of preparing same are described. These compounds are useful as tranquilizers, diuretics and antihypertensives.
Inventors
- 👤 Victor John Bauer
- 👤 Lawrence Leo Martin
- 👤 Brian John Duffy
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 09:42
CPC Classifications
C; C07; C07D; C07D239/00; C07D239/70
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
36 words
A compound of the formula ##STR3## wherein R 1 and R 2 are the same or different and represent hydrogen, halogen, lower alkoxy, lower alkyl, nitro or trifluoromethyl; or a physiologically tolerable acid addition salt thereof.
Claim 2
Dependent Claim
36 words
A compound of the formula ##STR3## wherein R 1 and R 2 are the same or different and represent hydrogen, halogen, lower alkoxy, lower alkyl, nitro or trifluoromethyl; or a physiologically tolerable acid addition salt thereof.
Claim 3
Dependent Claim
23 words
A compound as defined in claim 1 wherein R 1 and R 2 are the same or different and represent hydrogen or halogen.
Claim 4
Dependent Claim
40 words
A compound as defined in claim 1 wherein R 1 and R 2 are the same or different and represent hydrogen, chlorine or fluorine and occupy the para and ortho positions or the two ortho positions of the phenyl ring.
Claim 5
Dependent Claim
10 words
The compound as defined in claim 1 which is 3-(2,6-dichloroanilino)-2,4-diazabicyclo[3.2.1]oct-2-ene.
Claim 6
Dependent Claim
10 words
The compound as defined in claim 1 which is 3-(2-chloroanilino)-2,4-diazabicyclo[3.2.1]oct-2-ene.
Claim 7
Dependent Claim
9 words
The compound defined in claim 1 which is 3-(4-chloroanilino)-2,4-diazabicyclo[3.2.1]oct-2-ene.
Claim 8
Dependent Claim
9 words
The compound defined in claim 1 which is 3-(4-fluoroanilino)-2,4-diazabicyclo[3.2.1]oct-2-ene.
Claim 9
Dependent Claim
25 words
A method of depressing the central nervous system which comprises administering to a patient a pharmaceutically effective amount of a compound defined in claim 1.
Claim 10
Dependent Claim
22 words
A method of treating hypertension which comprises administering to a patient a pharmaceutically effective amount of a compound defined in claim 1.
Claim 11
Dependent Claim
22 words
A method of promoting diuresis which comprises administering to a patient a pharmaceutically effective amount of a compound defined in claim 1.
Claim 12
Dependent Claim
34 words
A pharmaceutical composition which comprises between about 0.5 and about 70 percent by weight of a compound defined in claim 1 as an essential active ingredient, the balance being a pharmaceutically acceptable carrier therefor.
References Cited (Backward Citations)
US2899434A
Cited
US3202660A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-05-16 | 1980-11-15 | 1981-05-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-05-16 | 1984-11-15 | 1985-05-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-05-16 | 1988-11-15 | 1989-05-17 | $7700.00 | Window Closed / Lapsed |