US4022773A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Cephalosporin esters
Assignee: Individual
•
Filing: 1975-08-25
•
Granted: 1977-05-10
•
Expires: 1995-08-25
Abstract
Abstract New esters of 7-acylamino-3-substituted-3-cephem-4-carboxylic acids and 1-oxides thereof have been prepared. The compounds are of value as intermediates for the preparation of various important cephalosporins.
Inventors
- 👤 Toshiyasu Ishimaru
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 22:06
CPC Classifications
C; C07; C07D; C07D499/00
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
95 words
A compound having the formula: ##STR12## , wherein A is phenylacetamido, phenoxyacetamido, formylamino, phthalimido, 2,2-dimethyl-3-nitroso-;b 4-phenyl-5-oxo-imidazolin-1-yl or 2-methyl-3-nitroso-4-phenyl-5-oxo-imidazolin-1-yl; Y is =S or =S--O; X is hydrogen or lower alkanoyloxy; R 1 is lower alkoxy, lower alkyl or phenyl and R 2 is lower alkoxycarbonyl, lower alkylcarbonyl or phenyl carbonyl, or a group of the formula; ##STR13## in which R 3 and R 4 , which may be the same or different, are hydrogen or lower alkyl or may, together with the nitrogen atom to which they are bonded and an oxygen atom, together form morpholino.
Claim 2
Dependent Claim
95 words
A compound having the formula: ##STR12## , wherein A is phenylacetamido, phenoxyacetamido, formylamino, phthalimido, 2,2-dimethyl-3-nitroso-;b 4-phenyl-5-oxo-imidazolin-1-yl or 2-methyl-3-nitroso-4-phenyl-5-oxo-imidazolin-1-yl; Y is =S or =S--O; X is hydrogen or lower alkanoyloxy; R 1 is lower alkoxy, lower alkyl or phenyl and R 2 is lower alkoxycarbonyl, lower alkylcarbonyl or phenyl carbonyl, or a group of the formula; ##STR13## in which R 3 and R 4 , which may be the same or different, are hydrogen or lower alkyl or may, together with the nitrogen atom to which they are bonded and an oxygen atom, together form morpholino.
Claim 3
Dependent Claim
12 words
A compound according to claim 1, in which A is phenylacetamido group.
Claim 4
Dependent Claim
12 words
A compound according ro claim 1, in which A is phenoxyacetamido group.
Claim 5
Dependent Claim
12 words
1'Methoxycarbonyl-2'-oxopropan-1'-yl ester of 7-phenylacetamido-3-methyl-3-cephem-4-carboxylic acid or its 1-oxide according to claim 1.
Claim 6
Dependent Claim
12 words
1'-Methoxycarbonyl-2'-oxopropan-1'-yl ester of 7-phenoxyacetamido-3-methyl-3-cephem-4-carboxylic acid or its 1-oxide according to claim 1.
Claim 7
Dependent Claim
12 words
1'-Ethoxycarbonyl-2'-oxopropan-1'-yl ester of 7-phenylacetamido-3-methyl-3-cephem-4-carboxylic acid or its 1-oxide according to claim 1.
Claim 8
Dependent Claim
13 words
1'-Ethoxycarbonyl-2'-oxopropan-1'-yl ester of 7-phenoxyacetamido-3-methyl-;b 3-cephem-4-carboxylic acid or its 1-oxide according to claim 1.
Claim 9
Dependent Claim
13 words
2', 4'-Dioxopentan-3'-yl ester of 7-phenylacetamido-3-methyl-3-cephem-4-carboxylic acid or its 1-oxide according to claim 1.
Claim 10
Dependent Claim
12 words
2',4'-Dioxopentan-3'-yl ester of 7-phenoxyacetamido-3-methyl-3-cephem-4-carboxylic acid or its 1-oxide according to claim 1.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-05-09 | 1980-11-08 | 1981-05-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-05-09 | 1984-11-08 | 1985-05-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-05-09 | 1988-11-08 | 1989-05-10 | $7700.00 | Window Closed / Lapsed |