Patent US4021545A successfully refreshed from Google Patents.
US4021545A
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Complement inhibitors
Assignee: Wyeth Holdings LLC
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Filing: 1976-07-12
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Granted: 1977-05-03
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Expires: 1996-07-12
Abstract
Abstract Inulin poly(H-sulfate) and salts thereof useful as complement inhibitors.
Inventors
- 👤 Vijay Gopalan Nair
- 👤 Joseph Peter Joseph
- 👤 Seymour Bernstein
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 23:35
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; A61K31/715; C; C08; C08B; C08B37/00; C08B37/0006; C08B37/0051; C08B37/0054
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
76 words
A method of inhibiting the complement system in a body fluid which comprises subjecting said body fluid to the action of an effective complement inhibiting amount of a compound selected from those of the formula: ##STR2## wherein R is selected from the group comprising --SO 3 A and --SO 3 .sup.⊖ HR'.sup.⊕, wherein A is hydrogen, alkaline earth or alkali metal; R' is triloweralkyl (C 1 -C 6 ) amine; and n is 20 through 35.
Claim 2
Independent Claim
76 words
A method of inhibiting the complement system in a body fluid which comprises subjecting said body fluid to the action of an effective complement inhibiting amount of a compound selected from those of the formula: ##STR2## wherein R is selected from the group comprising --SO 3 A and --SO 3 .sup.⊖ HR'.sup.⊕, wherein A is hydrogen, alkaline earth or alkali metal; R' is triloweralkyl (C 1 -C 6 ) amine; and n is 20 through 35.
Claim 3
Dependent Claim
13 words
A method according to claim 1 wherein the compound is inulin, poly(H-sulfate)sodium salt.
Claim 4
Dependent Claim
20 words
A method of claim 1 wherein the compound is inulin, poly(H-sulfate)sodium salt with triloweralkyl (C 1 -C 6 ) amine.
Claim 5
Independent Claim
72 words
A method of inhibiting the complement system in a warm-blooded animal which comprises administering to said animal an effective complement inhibiting amount of a compound selected from those of the formula: ##STR3## wherein R is selected from the group comprising --SO 3 A and --SO 3 .sup.⊖ HR'.sup.⊕, wherein A is hydrogen, alkaline earth or alkali metal; R' is triloweralkyl (C 1 -C 6 ) amine; and n is 20 through 35.
Claim 6
Independent Claim
72 words
A method of inhibiting the complement system in a warm-blooded animal which comprises administering to said animal an effective complement inhibiting amount of a compound selected from those of the formula: ##STR3## wherein R is selected from the group comprising --SO 3 A and --SO 3 .sup.⊖ HR'.sup.⊕, wherein A is hydrogen, alkaline earth or alkali metal; R' is triloweralkyl (C 1 -C 6 ) amine; and n is 20 through 35.
Claim 7
Dependent Claim
13 words
A method according to claim 4 wherein the compound is inulin, poly(H-sulfate)sodium salt.
Claim 8
Dependent Claim
20 words
A method according to claim 4 wherein the compound is inulin, poly(H-sulfate)salt with triloweralkyl (C 1 -C 6 ) amine.
References Cited (Backward Citations)
US3951949A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-05-02 | 1980-11-01 | 1981-05-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-05-02 | 1984-11-01 | 1985-05-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-05-02 | 1988-11-01 | 1989-05-03 | $7700.00 | Window Closed / Lapsed |