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US4018895A
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Aryloxyphenylpropylamines in treating depression
Assignee: Eli Lilly and Co
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Filing: 1975-09-17
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Granted: 1977-04-19
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Expires: 1995-09-17
Abstract
Abstract 3-Aryloxy-3-phenylpropylamines and acid additions salts thereof, useful as psychotropic agents, particularly as anti-depressants.
Inventors
- 👤 Bryan B. Molloy
- 👤 Klaus K. Schmiegel
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 19:50
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/13; A61K31/135
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
82 words
A method of treating human suffering from depression which comprises administering to said human an effective antidepressant dose of a compound of the formula: ##STR7## wherein each R' is independently hydrogen or methyl; wherein R is naphthyl or ##STR8## wherein R" and R'" are halo, trifluoromethyl, C 1 -C 4 alkyl, C 1 -C 3 alkyloxy or C 3 -C 4 alkenyl; and wherein n and m are 0, 1 or 2; and acid addition salts thereof formed with a pharmaceutically-acceptable acid.
Claim 2
Independent Claim
82 words
A method of treating human suffering from depression which comprises administering to said human an effective antidepressant dose of a compound of the formula: ##STR7## wherein each R' is independently hydrogen or methyl; wherein R is naphthyl or ##STR8## wherein R" and R'" are halo, trifluoromethyl, C 1 -C 4 alkyl, C 1 -C 3 alkyloxy or C 3 -C 4 alkenyl; and wherein n and m are 0, 1 or 2; and acid addition salts thereof formed with a pharmaceutically-acceptable acid.
Claim 3
Dependent Claim
18 words
A method according to claim 1, in which from 1 to 200 mg./day of the compound is administered.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-04-18 | 1980-10-18 | 1981-04-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-04-18 | 1984-10-18 | 1985-04-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-04-18 | 1988-10-18 | 1989-04-19 | $7700.00 | Window Closed / Lapsed |