US4016209A
Expired / Lapsed
US
⏱️ 0.0 years remaining
3-[N'-(3-Halopropyl)-N-'-methylamino]-N,N,N-trimethyl-1-propanaminium halide and acid addition salts thereof
Assignee: Merck and Co Inc
•
Filing: 1975-04-23
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Granted: 1977-04-05
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Expires: 1995-04-23
Abstract
Abstract Novel linear, unbranched, non-cross-linked polymers particularly poly-[{methyl-(3-trimethylammoniopropyl)imino} trimethylene dihalide] are prepared by the polymerization of the novel monomer, 3-[N'-(3-halopropyl)-N'-methylamino]-N,N,N-trimethyl-l-propanaminium halide, or an acid addition salt thereof preferably in an oxygen excluded environment, e.g., under nitrogen or argon. The polymer, especially after modification of terminal groups, is an excellent oral anticholesterolemic.
Inventors
- 👤 Arthur F. Wagner
- 👤 Tsung-Ying Shen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 16:24
CPC Classifications
C; C08; C08G; C08G73/00; C08G73/02; C08G73/0206; C08G73/0213; C08G73/0226; C07; C07C; C07C209/00; C07C209/68; C07C209/74
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
52 words
A compound of the formula: ##STR4## where X is chloro, bromo, or iodo, and y is chloride, bromide, iodide or a pharmaceutically acceptable anion were a is the anionic charge on Y, m is a number such that the product of m and a is 1, and hydroholic acid addition salts thereof.
Claim 2
Dependent Claim
52 words
A compound of the formula: ##STR4## where X is chloro, bromo, or iodo, and y is chloride, bromide, iodide or a pharmaceutically acceptable anion were a is the anionic charge on Y, m is a number such that the product of m and a is 1, and hydroholic acid addition salts thereof.
Claim 3
Dependent Claim
10 words
A compound according to claim 1 where X is bromo.
Claim 4
Dependent Claim
10 words
A compound according to claim 1 where X is chloro.
Claim 5
Dependent Claim
10 words
A compound according to claim 1 where X is iodo.
Claim 6
Dependent Claim
10 words
A compound according to claim 1 where Y is bromide.
Claim 7
Dependent Claim
10 words
A compound according to claim 1 where Y is chloride.
Claim 8
Dependent Claim
10 words
A compound according to claim 1 where Y is iodide.
Claim 9
Dependent Claim
10 words
A compound according to claim 2 where Y is bromide.
Claim 10
Dependent Claim
10 words
A compound according to claim 3 where y is chloride.
Claim 11
Dependent Claim
3 words
3-[N'-(3-chloropropyl)-N'-methylamino]-N,N,N-trimethyl-1-propanaminium chloride hydrochloride.
Claim 12
Dependent Claim
3 words
3-[N'-(3-chloropropyl)-N'-methylamino]-N,N,N-trimethyl-1-propanaminium chloride hydrochloride.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-04-04 | 1980-10-04 | 1981-04-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-04-04 | 1984-10-04 | 1985-04-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-04-04 | 1988-10-04 | 1989-04-05 | $7700.00 | Window Closed / Lapsed |