Patent US4013792A successfully refreshed from Google Patents.
US4013792A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for the production of base for topical steroids
Assignee: Warner Lambert Co LLC
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Filing: 1975-09-18
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Granted: 1977-03-22
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Expires: 1995-09-18
Abstract
Abstract A clear gel composition containing a topically active anti-inflammatory steroid and a neomycin salt is disclosed. The clear gel composition is prepared by dissolving the steroid in a polyhydroxy alcohol/lower alcohol solvent, a major proportion of the polyhydroxy alcohol solvent being propylene glycol, and adding a hydroxycellulose ingredient; an aqueous solution of the neomycin salt is then added to the steroid formulation and, upon the addition of an alkali metal chloride salt, such as sodium chloride, a clear gel is obtained. The pH may be adjusted to 4-5. The resulting composition is indicated for the relief of corticosteroid-responsive dermatoses.
Inventors
- 👤 Martin L. Eichman
- 👤 Susan C. Belsole
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 18:46
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
77 words
A stable aqueous clear gel composition comprising about 0.02625% by weight of betamethasone 17-benzoate about 0.5% by weight of neomycin sulfate, about 35% by weight propylene glycol, about 16.67% by weight ethanol, about 1.5% by weight of hydroxypropyl methylcellulose having a viscosity of from about 80 to about 120,000 centipoises, about 1% by weight of sodium chloride and a sufficient amount of 1N hydrochloric acid to adjust the pH of the composition to about 4.0 to 5.0.
Claim 2
Dependent Claim
77 words
A stable aqueous clear gel composition comprising about 0.02625% by weight of betamethasone 17-benzoate about 0.5% by weight of neomycin sulfate, about 35% by weight propylene glycol, about 16.67% by weight ethanol, about 1.5% by weight of hydroxypropyl methylcellulose having a viscosity of from about 80 to about 120,000 centipoises, about 1% by weight of sodium chloride and a sufficient amount of 1N hydrochloric acid to adjust the pH of the composition to about 4.0 to 5.0.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-03-21 | 1980-09-20 | 1981-03-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-03-21 | 1984-09-20 | 1985-03-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-03-21 | 1988-09-20 | 1989-03-22 | $7700.00 | Window Closed / Lapsed |