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Patent US4011340A successfully refreshed from Google Patents.
US4011340A
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US
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Hypolipidemic bis(pivaloylbenzyl) ureas
Assignee: Sandoz Inc
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Filing: 1975-10-28
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Granted: 1977-03-08
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Expires: 1995-10-28
Abstract
Abstract Pivaloyl benzyl ureas, e.g., 1,1-bis(4-pivaloylbenzyl)-3-methyl urea, are prepared by reacting a corresponding 4", 4'"-iminodimethylene-di-tert. alkylophenones with an alkyl isocyanate, and are useful as hypolipidemic agents.
Inventors
- 👤 Jeffrey Nadelson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 12:28
CPC Classifications
C; C07; C07C; C07C275/00; C07C275/04; C07C275/20; C07C275/24
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
52 words
A compound of the formula ##STR6## where R 1 represents lower alkyl having 1 to 4 carbon atoms, and R 2 each independently represents hydrogen, halo having an atomic weight of about 19 to 36, and R 3 and R 4 each independently represent lower alkyl having 1 to 2 carbon atoms.
Claim 2
Dependent Claim
52 words
A compound of the formula ##STR6## where R 1 represents lower alkyl having 1 to 4 carbon atoms, and R 2 each independently represents hydrogen, halo having an atomic weight of about 19 to 36, and R 3 and R 4 each independently represent lower alkyl having 1 to 2 carbon atoms.
Claim 3
Dependent Claim
15 words
A compound of the formula ##STR7## where R 1 is as defined in claim 1.
Claim 4
Dependent Claim
15 words
A compound of the formula ##STR8## where R 2 is as defined in claim 1.
Claim 5
Dependent Claim
9 words
The compound of claim 2 which is 1,1-bis(4-pivaloylbenzyl)-3-methyl urea.
Claim 6
Dependent Claim
25 words
A composition for lowering lipid levels comprising a hypolipidemically effective amount of the compound of claim 1 and a pharmaceutically acceptable diluent or carrier therefor.
Claim 7
Dependent Claim
26 words
A method of treating lipidemia which comprises administering to a mammal in need of said treatment a hypolipidemically effective amount of a compound of claim 1.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-03-07 | 1980-09-06 | 1981-03-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-03-07 | 1984-09-06 | 1985-03-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-03-07 | 1988-09-06 | 1989-03-08 | $7700.00 | Window Closed / Lapsed |