Butyrophenone derivatives
Abstract
Abstract Novel butyrophenone derivatives of the formula: ##STR1## wherein R 1 represents a hydroxyl group or ##STR2## (wherein R 6 and R 7 are each a hydrogen atom or a lower alkyl group or, when taken together with the adjacent nitrogen atom, may form a heterocyclic group), R 2 represents an optionally substituted phenyl group or ##STR3## (wherein R 8 and R 9 are each a hydrogen atom or a lower alkyl group or, when taken together with the adjacent nitrogen atom, may form a heterocyclic group), R 4 represents a hydrogen atom, a lower alkyl group or an optionally substituted phenyl group, R 5 represents a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group or a trifluoromethyl group, R 10 represents a hydrogen atom or an acyl group represented by R 3 CO- (wherein R 3 is a hydrogen atom, a lower alkyl group or an optionally substituted phenyl group) and Z represents two hydrogen atoms or an oxygen atom, provided that when Z is an oxygen atom and R 1 is ##STR4## R 10 can not be a hydrogen atom, and their acid addition salts, which are useful as central and autonomic nervous system depressants.
Inventors
- 👤 Kikuo Sasajima
- 👤 Masaru Nakao
- 👤 Isamu Maruyama
- 👤 Keiichi Ono
- 👤 Shigenari Katayama
- 👤 Shigeho Inaba
- 👤 Hisao Yamamoto
Bibliographic Details
Claims Analysis
Total Claims: 4References Cited (Backward Citations)
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