US4004003A
Expired / Lapsed
US
⏱️ 0.0 years remaining
25-Hydroxycalciferol compounds for treatment of steroid-induced osteoporosis
Assignee: Pharmacia and Upjohn Co
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Filing: 1975-10-06
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Granted: 1977-01-18
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Expires: 1995-10-06
Abstract
Abstract A process for the prevention or treatment of osteoporosis induced as a side effect of the administration of glucocorticoid steroids by the administration of a compound of the formula: ##STR1## WHEREIN R 1 and R.sub. 2 are the same or different radicals selected from the group consisting of hydrogen, alkyl of less than 9 carbon atoms, and phenyl; R 3 and R.sub. 5 are selected from the group consisting of hydrogen and lower acyl; n is an integer, selected from the group consisting of 2, 3, and 4; or a hydrate thereof in association with a pharmaceutical carrier to a human or animal being treated or having been treated with a gluco-corticoid hormone.
Inventors
- 👤 John C. Babcock
- 👤 J. Allan Campbell
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 12:58
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/59; A61K31/593
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
94 words
A process for the therapeutic or prophylactic treatment of gluco-corticoid hormone-induced osteoporosis comprising the administration of a compound of the formula: ##STR3##wherein R 1 and R 2 are the same or different radicals selected from the group consisting of hydrogen, alkyl of less than 9 carbon atoms, and phenyl; R 3 and R 5 are selected from the group consisting of hydrogen and lower acyl; n is an integer, selected from the group consisting of 2, 3, and 4; or a hydrate thereof in association with a pharmaceutical carrier to a human or animal.
Claim 2
Dependent Claim
94 words
A process for the therapeutic or prophylactic treatment of gluco-corticoid hormone-induced osteoporosis comprising the administration of a compound of the formula: ##STR3##wherein R 1 and R 2 are the same or different radicals selected from the group consisting of hydrogen, alkyl of less than 9 carbon atoms, and phenyl; R 3 and R 5 are selected from the group consisting of hydrogen and lower acyl; n is an integer, selected from the group consisting of 2, 3, and 4; or a hydrate thereof in association with a pharmaceutical carrier to a human or animal.
Claim 3
Dependent Claim
21 words
The process of claim 1 wherein the amount of compound administered is from about 1 to about 500 micrograms per day.
Claim 4
Dependent Claim
11 words
The process of claim 1 wherein the compound administered is 25-hydroxycholecalciferol.
References Cited (Backward Citations)
US3772361A
Cited
US3901928A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-01-18 | 1980-07-19 | 1981-01-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-01-18 | 1984-07-19 | 1985-01-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-01-18 | 1988-07-19 | 1989-01-18 | $7700.00 | Window Closed / Lapsed |