Patent US4002731A successfully refreshed from Google Patents.
US4002731A
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US
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Diagnostic process using sodium tyropanoate
Assignee: STWB Inc
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Filing: 1974-06-17
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Granted: 1977-01-11
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Expires: 1994-06-17
Abstract
Abstract Divided doses or sustained release formulations of sodium tyropanoate upon oral administration provide adequate gallbladder visualization with substantially lower blood levels than are obtained with conventional single dose administration.
Inventors
- 👤 Thomas W. Skulan
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 11:27
CPC Classifications
A; A61; A61K; A61K49/00; A61K49/04; A61K49/0433; A61K49/0447; A61K49/0495; A61K9/00; A61K9/48; A61K9/50; A61K9/5005; A61K9/5015; A61K9/5021; A61K9/5036; A61K9/5042; A61K9/5047; A61K9/5084
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
111 words
A process which comprises administering orally to a mammal possessing a gallbladder, a single undivided dose in a sustained or controlled release formulation or intermittently over a period of between about four and about ten hours, an amount of sodium tyropanoate of between about 25 and 100 milligrams per kilogram of body weight of the mammal, whereby a concentration of iodine in the gallbladder sufficient to provide adequate X-ray visualization of the gallbladder is obtained, while maintaining the maximum iodine concentration in the blood significantly lower than the maximum iodine concentration in the blood obtained by oral administration of an initial single dose of the same total amount of sodium tyropanoate.
Claim 2
Dependent Claim
111 words
A process which comprises administering orally to a mammal possessing a gallbladder, a single undivided dose in a sustained or controlled release formulation or intermittently over a period of between about four and about ten hours, an amount of sodium tyropanoate of between about 25 and 100 milligrams per kilogram of body weight of the mammal, whereby a concentration of iodine in the gallbladder sufficient to provide adequate X-ray visualization of the gallbladder is obtained, while maintaining the maximum iodine concentration in the blood significantly lower than the maximum iodine concentration in the blood obtained by oral administration of an initial single dose of the same total amount of sodium tyropanoate.
Claim 3
Dependent Claim
35 words
The process according to claim 1 in which the sodium tyropanoate is administered in from three to six approximately equally divided doses at approximately equal intervals over a period of between 4 and 10 hours.
Claim 4
Dependent Claim
87 words
A process which comprises administering orally to a mammal possessing a gallbladder a sustained release formulation comprising an amount of sodium tyropanoate of between about 25 and 100 milligrams per kilogram of body weight of the mammal, whereby a concentration of iodine in the gallbladder sufficient to provide adequate X-ray visualization of the gallbladder is obtained while maintaining the maximum iodine concentration in the blood significantly lower than the maximum iodine concentration in the blood obtained by oral administration of the same amount of sodium tyropanoate alone.
Claim 5
Dependent Claim
87 words
A process which comprises administering orally to a mammal possessing a gallbladder a sustained release formulation comprising an amount of sodium tyropanoate of between about 25 and 100 milligrams per kilogram of body weight of the mammal, whereby a concentration of iodine in the gallbladder sufficient to provide adequate X-ray visualization of the gallbladder is obtained while maintaining the maximum iodine concentration in the blood significantly lower than the maximum iodine concentration in the blood obtained by oral administration of the same amount of sodium tyropanoate alone.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-01-11 | 1980-07-12 | 1981-01-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-01-11 | 1984-07-12 | 1985-01-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-01-11 | 1988-07-12 | 1989-01-11 | $7700.00 | Window Closed / Lapsed |