Patent US4002531A successfully refreshed from Google Patents.
US4002531A
Expired / Lapsed
US
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Modifying enzymes with polyethylene glycol and product produced thereby
Assignee: Pierce Chemical Co
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Filing: 1976-01-22
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Granted: 1977-01-11
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Expires: 1996-01-22
Abstract
Abstract A process is disclosed for the preparation of the monoalkyl polyethyleneglycol derivatives of enzymes containing free amino groups. The process involves reductively alkylating the free amino groups of the enzyme with the aldehyde derivative of a monoalkyl polyethyleneglycol.
Inventors
- 👤 Garfield P. Royer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 16:06
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/43; A61K38/46; A61K38/48; A61K38/482; A61K38/4826; A61K47/00; A61K47/50; A61K47/51; A61K47/56; A61K47/59; A61K47/60; C; C12; C12Y; C12Y304/00; C12Y304/21; C12Y304/21004
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
35 words
A process for the preparation of the monoalkyl polyethyleneglycol derivative of an enzyme containing free amino groups comprising reductively alkylating the free amino groups of the enzyme with the aldehyde derivative of a monoalkyl polyethyleneglycol.
Claim 2
Dependent Claim
35 words
A process for the preparation of the monoalkyl polyethyleneglycol derivative of an enzyme containing free amino groups comprising reductively alkylating the free amino groups of the enzyme with the aldehyde derivative of a monoalkyl polyethyleneglycol.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-01-11 | 1980-07-12 | 1981-01-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-01-11 | 1984-07-12 | 1985-01-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-01-11 | 1988-07-12 | 1989-01-11 | $7700.00 | Window Closed / Lapsed |