Patent US4000299A successfully refreshed from Google Patents.
US4000299A
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1-(Imidazol-1-yl)-1-[4-(4-chlorophenyl)phenoxy]-3,3-dimethylbutan-2-one, its salts and a process for their use
Assignee: Bayer AG
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Filing: 1975-05-27
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Granted: 1976-12-28
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Expires: 1995-05-27
Abstract
Abstract 1-(Imidazol-1-yl)-1-[4-(4-chlorophenyl)phenoxy]-3,3-dimethylbutan-2-one possesses antimicrobial activity, in particular antimycotic activity. The compound is prepared through the condensation of imidazole with 1-chloro-1-[4-(4-chlorophenyl)phenoxy]-3,3-dimethylbutan-2-one.
Inventors
- 👤 Wolfgang Kramer
- 👤 Karl Heinz Buchel
- 👤 Manfred Plempel
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 11:40
CPC Classifications
C; C07; C07D; C07D231/00; C07D231/02; C07D231/10; C07D231/12; A; A61; A61P; A61P31/00; A61P31/04; A61P31/10; C07C; C07C45/00; C07C45/61; C07C45/67; C07C45/68; C07C45/70; C07C45/71; C07C49/00; C07C49/20; C07C49/255; C07D233/00; C07D233/54; C07D233/56; C07D249/00; C07D249/02; C07D249/08
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
18 words
A compound selected from the group consisting of 1-(imidazol-1-yl)-1-[4-(4-chlorophenyl)phenoxy]-3,3-dimethylbutan-2-one and the pharmaceutically acceptable nontoxic acid addition salts thereof.
Claim 2
Dependent Claim
18 words
A compound selected from the group consisting of 1-(imidazol-1-yl)-1-[4-(4-chlorophenyl)phenoxy]-3,3-dimethylbutan-2-one and the pharmaceutically acceptable nontoxic acid addition salts thereof.
Claim 3
Dependent Claim
9 words
The compound according to claim 1 which is 1-(imidazol-1-yl)-1-[4-(4-chlorophenyl)phenoxy]-3,3-dimethylbutan-2-one.
Claim 4
Dependent Claim
37 words
A compound according to claim 1 which is the salt of said 1-(imidazol-1-yl)-1- [4-(4-chlorophenyl)phenoxy]-3,3-dimethylbutan-2-one with a hydrogen halide acid, phosphoric acid, sulfuric acid, nitric acid, a sulfonic acid, a monobasic carboxylic acid or a dibasic carboxylic acid.
Claim 5
Dependent Claim
9 words
The compound of claim 1 which is 1-(imidazol-1-yl)-1-[4-(4-chlorophenyl)phenoxy]-3,3-dimethylbutan-2-one hydrochloride.
Claim 6
Dependent Claim
9 words
The compound of claim 1 which is 1-(imidazol-1-yl)-1-[4-(4-chlorophenyl)phenoxy]-3,3-dimethylbutan-2-one nitrate.
Claim 7
Dependent Claim
9 words
The compound of claim 1 which is 1-(imidazol-1-yl)-1-[4-(4-chlorophenyl)phenoxy]-3,3-dimethylbutan-2-one phosphate.
Claim 8
Dependent Claim
9 words
The compound of claim 1 which is 1-(imidazol-1-yl)-1-[4-(4-chlorophenyl)phenoxy]-3,3-dimethylbutan-2-one sulfate.
Claim 9
Dependent Claim
9 words
The compound of claim 1 which is 1-(imidazol-1-yl)-1-[4-(4-chlorophenyl)phenoxy]-3,3-dimethylbutan-2-one oxalate.
Claim 10
Dependent Claim
29 words
The method of combatting microbial infections in humans and animals which comprises administering to said human or animal an antimicrobially effective amount of a compound according to claim 1.
Claim 11
Dependent Claim
23 words
A pharmaceutical composition comprising an antimicrobially effective amount of a compound according to claim 1 in combination with a pharmaceutical carrier or diluent.
References Cited (Backward Citations)
DE2105490A1
Cited
US3812142A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-12-28 | 1980-06-28 | 1980-12-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-12-28 | 1984-06-28 | 1984-12-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-12-28 | 1988-06-28 | 1988-12-28 | $7700.00 | Window Closed / Lapsed |