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Antitumor derivatives of periodate-oxidized nucleosides

Assignee: Wyeth LLC
•
Filing: 1975-06-10
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Granted: 1976-12-28
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Expires: 1995-06-10
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Abstract

Abstract The reaction of the periodate oxidation product from inosine, adenosine, or cytidine with methanol or ethanol affords a product having activity against lymphocytic leukemia P388 in mice.

Inventors

  • 👤 William Dvonch
  • 👤 Harvey E. Alburn

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 12:22
CPC Classifications
C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/06; C07H19/16

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 12 words
A compound of the formula ##STR4## wherein R is methyl or ethyl.
Claim 2
Dependent Claim 12 words
A compound of the formula ##STR4## wherein R is methyl or ethyl.
Claim 3
Dependent Claim 10 words
A compound as defined in claim 1 which is 9-[3(5)-hydroxy-6-hydroxymethyl-5(3)-methoxy-p-dioxan-2-yl]-9H-purin-6-ol.
Claim 4
Dependent Claim 10 words
A compound as defined in claim 1 which is 9-[3(5)-ethoxy-5(3)-hydroxy-6-hydroxymethyl-p-dioxan-2-yl]-9H-purin-6-ol.
Claim 5
Dependent Claim 10 words
A compound as defined in claim 1 which is 6-amino-9-[3(5)-hydroxy-6-hydroxymethyl-6(3)-methoxy-p-dioxan-2-yl]-9H-purine.
Claim 6
Dependent Claim 10 words
A compound as defined in claim 1 which is 6-amino-[3(5)-ethoxy-5(3)-hydroxy-6-hydroxymethyl-p-dioxane-2-yl]-9H-purine.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1979-12-28 1980-06-28 1980-12-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1983-12-28 1984-06-28 1984-12-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1987-12-28 1988-06-28 1988-12-28 $7700.00 Window Closed / Lapsed

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