Patent US3987105A successfully refreshed from Google Patents.
US3987105A
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Process for methoxymethylation of phenolic hydroxyl groups
Assignee: Wyeth LLC
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Filing: 1975-04-25
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Granted: 1976-10-19
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Expires: 1995-04-25
Abstract
Abstract A process for preparing methoxymethyl ethers of phenols utilizing dimethoxy methane is described. The thus-protected phenols are useful as intermediates in a variety of reaction sequences.
Inventors
- 👤 John P. Yardley
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 09:12
CPC Classifications
C; C07; C07C; C07C47/00; C07C47/52; C07C47/575; C07C45/00; C07C45/61; C07C45/67; C07C45/68; C07C45/70; C07C45/71
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
112 words
A process for preparing a compound of the structure: ##SPC5## wherein R and R 1 may be the same or different and are chosen from the group consisting of hydrogen, alkyl of from 1 to 6 carbon atoms, alkoxy of from 1 to 6 carbon atoms, m-halo, p-halo, m-nitro, p-nitro m-acylamino, p-acylamino, m-acyl and p-acyl wherein the term acyl is a substituent of the structure ##EQU1## wherein A is hydrogen or alkyl of 1 to 5 carbon atoms; which comprises refluxing a compound of the structure: ##SPC6## wherein R and R 1 are as defined above, with dimethoxymethane and an acid catalyst in the presence of type 3A or 4A molecular sieves.
Claim 2
Dependent Claim
112 words
A process for preparing a compound of the structure: ##SPC5## wherein R and R 1 may be the same or different and are chosen from the group consisting of hydrogen, alkyl of from 1 to 6 carbon atoms, alkoxy of from 1 to 6 carbon atoms, m-halo, p-halo, m-nitro, p-nitro m-acylamino, p-acylamino, m-acyl and p-acyl wherein the term acyl is a substituent of the structure ##EQU1## wherein A is hydrogen or alkyl of 1 to 5 carbon atoms; which comprises refluxing a compound of the structure: ##SPC6## wherein R and R 1 are as defined above, with dimethoxymethane and an acid catalyst in the presence of type 3A or 4A molecular sieves.
Claim 3
Dependent Claim
14 words
The process of claim 1 wherein R is hydrogen and R 1 is m-formyl.
Claim 4
Dependent Claim
23 words
The process of claim 1 wherein a sulfonic acid is utilized as catalyst and either chloroform, or methylene chloride is utilized as solvent.
Claim 5
Dependent Claim
14 words
The process of claim 3 wherein R is hydrogen and R 1 is m-formyl.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-10-19 | 1980-04-19 | 1980-10-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-10-19 | 1984-04-19 | 1984-10-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-10-19 | 1988-04-19 | 1988-10-19 | $7700.00 | Window Closed / Lapsed |