Patent US1248444A successfully refreshed from Google Patents.
Patent US3985896A successfully refreshed from Google Patents.
US3985896A
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US
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Benzophenalenofurans
Assignee: GlaxoSmithKline LLC
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Filing: 1975-07-15
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Granted: 1976-10-12
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Expires: 1995-07-15
Abstract
Abstract The compounds are benzophenalenofurans having pharmacological activity, in particular, coronary vasodilator activity.
Inventors
- 👤 L. Martin Brenner
- 👤 Charles K. Brush
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 13:52
CPC Classifications
C; C07; C07D; C07D307/00; C07D307/77; C07D307/78; C07D307/79; C07D307/80
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
58 words
A compound of the formula: ##SPC5## or a pharmaceutically acceptable acid addition salt thereof, in which: R 1 is hydrogen or lower alkyl and R 2 is lower alkyl or R 1 and R 2 together with the nitrogen atom to which they are attached form a pyrrolidine, piperidine, or perhydroazepine ring; and n is 2 or 3.
Claim 2
Dependent Claim
58 words
A compound of the formula: ##SPC5## or a pharmaceutically acceptable acid addition salt thereof, in which: R 1 is hydrogen or lower alkyl and R 2 is lower alkyl or R 1 and R 2 together with the nitrogen atom to which they are attached form a pyrrolidine, piperidine, or perhydroazepine ring; and n is 2 or 3.
Claim 3
Dependent Claim
21 words
A compound according to claim 1 in which R 1 is hydrogen or lower alkyl and R 2 is lower alkyl.
Claim 4
Dependent Claim
11 words
A compound according to claim 2 in which n is 2.
Claim 5
Dependent Claim
10 words
A compound according to claim 3 being the compound 3-(2-diethylaminoethoxy)-7-oxo-7H-benzo[b]phenaleno-[2,1-]furan.
Claim 6
Dependent Claim
25 words
A pharmaceutical composition having coronary vasodilator activity comprising a pharmaceutical carrier and in an effective amount to produce said activity a compound of claim 1.
Claim 7
Dependent Claim
25 words
A method of producing coronary vasodilation comprising administering internally to an animal in an effective amount to produce said activity a compound of claim 1.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-10-12 | 1980-04-12 | 1980-10-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-10-12 | 1984-04-12 | 1984-10-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-10-12 | 1988-04-12 | 1988-10-12 | $7700.00 | Window Closed / Lapsed |