Patent DE448637C successfully refreshed from Google Patents.
Patent US3983144A successfully refreshed from Google Patents.
US3983144A
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US
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Novel 11β-alkyl steroids of the estrane series
Assignee: Akzona Inc
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Filing: 1974-12-04
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Granted: 1976-09-28
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Expires: 1994-12-04
Abstract
Abstract The present invention relates to novel steroids of the estrane series having the general formula I: ##SPC1## wherein R 1 and R 2 = an alkyl group having 1-4 carbon atoms, R 3 = oxygen or (αP)(βQ), wherein P = hydrogen or a saturated or an unsaturated alkyl group having 1-4 carbon atoms, and Q = a free, esterified or etherified hydroxyl group, and A double bond is present departing from carbon atom 5, and to the preparation thereof. The compounds according to the invention possess very valuable anabolic, androgenic, estrogenic, anti-estrogenic, progestative, anti-progestative, ovulation-inhibiting and gonad-inhibiting properties and are furthermore of value owing to their peripheral anti-fertility activity.
Inventors
- 👤 Johannes Antonius Joseph Leemhuis
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 02:53
CPC Classifications
C; C07; C07J; C07J11/00
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
104 words
Novel steroids of the estrane series having the general formula I: ##SPC5## wherein R 1 and R 2 = an alkyl group having 1-4 carbon atoms, R 3 = o or (α P) (β Q), wherein P = h or a saturated or an unsaturated alkyl group having 1-4 carbon atoms, and Q = hydroxy, acyloxy derived from an organic carboxylic acid having 1-18 carbon atoms, or an ether group selected from the group consisting of saturated or unsaturated alkoxy having 1-4 carbon atoms, cycloalkoxy having 5 or 6 carbon atoms and tetrahydropyranyloxy and a double bond is present departing from carbon atom 5.
Claim 2
Dependent Claim
104 words
Novel steroids of the estrane series having the general formula I: ##SPC5## wherein R 1 and R 2 = an alkyl group having 1-4 carbon atoms, R 3 = o or (α P) (β Q), wherein P = h or a saturated or an unsaturated alkyl group having 1-4 carbon atoms, and Q = hydroxy, acyloxy derived from an organic carboxylic acid having 1-18 carbon atoms, or an ether group selected from the group consisting of saturated or unsaturated alkoxy having 1-4 carbon atoms, cycloalkoxy having 5 or 6 carbon atoms and tetrahydropyranyloxy and a double bond is present departing from carbon atom 5.
Claim 3
Dependent Claim
30 words
Novel estrane compounds having the general formula III ##SPC6## wherein R 1 and R 3 have the meanings as indicated in claim 1, and R 4 = methyl or ethyl.
Claim 4
Dependent Claim
38 words
Novel estrane compounds having the general formula III of claim 2, wherein R 3 and R 4 have the meanings as indicated in claim 2 and R 1 is an alkyl group having 2 or 3 carbon atoms.
Claim 5
Dependent Claim
30 words
Novel estrane compounds having the general formula III of claim 2, wherein R 3 and R 4 have the meanings as indicated in claim 2 and R 1 is ethyl.
Claim 6
Dependent Claim
6 words
11β-Ethyl-17α-ethinyl-Δ 4 -estren-17β-ol and its 17β-acylates.
Claim 7
Dependent Claim
6 words
11β-Ethyl-17α-ethinyl-Δ 4 -estren-17β-ol and its 17β-acylates.
Claim 8
Dependent Claim
15 words
Pharmaceutical preparations containing one or more of the compounds of claim 1 as active constituent.
References Cited (Backward Citations)
US3032469A
Cited
GB996308A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-09-28 | 1980-03-29 | 1980-09-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-09-28 | 1984-03-29 | 1984-09-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-09-28 | 1988-03-29 | 1988-09-28 | $7700.00 | Window Closed / Lapsed |