§
Luxuse
Patent Intelligence
Sign In
← Back to Patent Explorer
US3983144A Expired / Lapsed US ⏱️ 0.0 years remaining

Novel 11β-alkyl steroids of the estrane series

Assignee: Akzona Inc
•
Filing: 1974-12-04
•
Granted: 1976-09-28
•
Expires: 1994-12-04
📄 Original PDF 🌐 Google Patents 🔄 Sync Now

Abstract

Abstract The present invention relates to novel steroids of the estrane series having the general formula I: ##SPC1## wherein R 1 and R 2 = an alkyl group having 1-4 carbon atoms, R 3 = oxygen or (αP)(βQ), wherein P = hydrogen or a saturated or an unsaturated alkyl group having 1-4 carbon atoms, and Q = a free, esterified or etherified hydroxyl group, and A double bond is present departing from carbon atom 5, and to the preparation thereof. The compounds according to the invention possess very valuable anabolic, androgenic, estrogenic, anti-estrogenic, progestative, anti-progestative, ovulation-inhibiting and gonad-inhibiting properties and are furthermore of value owing to their peripheral anti-fertility activity.

Inventors

  • 👤 Johannes Antonius Joseph Leemhuis

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-03 12:19
CPC Classifications
C; C07; C07J; C07J11/00

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 104 words
Novel steroids of the estrane series having the general formula I: ##SPC5## wherein R 1 and R 2 = an alkyl group having 1-4 carbon atoms, R 3 = o or (α P) (β Q), wherein P = h or a saturated or an unsaturated alkyl group having 1-4 carbon atoms, and Q = hydroxy, acyloxy derived from an organic carboxylic acid having 1-18 carbon atoms, or an ether group selected from the group consisting of saturated or unsaturated alkoxy having 1-4 carbon atoms, cycloalkoxy having 5 or 6 carbon atoms and tetrahydropyranyloxy and a double bond is present departing from carbon atom 5.
Claim 2
Dependent Claim 104 words
Novel steroids of the estrane series having the general formula I: ##SPC5## wherein R 1 and R 2 = an alkyl group having 1-4 carbon atoms, R 3 = o or (α P) (β Q), wherein P = h or a saturated or an unsaturated alkyl group having 1-4 carbon atoms, and Q = hydroxy, acyloxy derived from an organic carboxylic acid having 1-18 carbon atoms, or an ether group selected from the group consisting of saturated or unsaturated alkoxy having 1-4 carbon atoms, cycloalkoxy having 5 or 6 carbon atoms and tetrahydropyranyloxy and a double bond is present departing from carbon atom 5.
Claim 3
Dependent Claim 30 words
Novel estrane compounds having the general formula III ##SPC6## wherein R 1 and R 3 have the meanings as indicated in claim 1, and R 4 = methyl or ethyl.
Claim 4
Dependent Claim 38 words
Novel estrane compounds having the general formula III of claim 2, wherein R 3 and R 4 have the meanings as indicated in claim 2 and R 1 is an alkyl group having 2 or 3 carbon atoms.
Claim 5
Dependent Claim 30 words
Novel estrane compounds having the general formula III of claim 2, wherein R 3 and R 4 have the meanings as indicated in claim 2 and R 1 is ethyl.
Claim 6
Dependent Claim 6 words
11β-Ethyl-17α-ethinyl-Δ 4 -estren-17β-ol and its 17β-acylates.
Claim 7
Dependent Claim 6 words
11β-Ethyl-17α-ethinyl-Δ 4 -estren-17β-ol and its 17β-acylates.
Claim 8
Dependent Claim 15 words
Pharmaceutical preparations containing one or more of the compounds of claim 1 as active constituent.

References Cited (Backward Citations)

US3032469A Cited
GB996308A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1979-09-28 1980-03-29 1980-09-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1983-09-28 1984-03-29 1984-09-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1987-09-28 1988-03-29 1988-09-28 $7700.00 Window Closed / Lapsed

Assigned Categories & Tags

No categories assigned to this patent yet.

Assign Category Tag